Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Thrue Charlotte Albaeck"'
Autor:
O. Olsen, Ellen Marie Straarup, Henrik Frydenlund Hansen, L. Hildebrandt-Eriksen, Thrue Charlotte Albaeck, Jens Bo Hansen, L. S. Kjaerulff, Majken Westergaard, Phil Kearney, L. W. Dalby
Publikováno v:
Journal of Clinical Oncology. 24:14581-14581
14581 Background: SPC2968 is a short (16-mer), oligonucleotide antagonist of Hif-1α mRNA in which potency has been enhanced through incorporation of Locked Nucleic Acid. Over-expression of Hif-1α has been correlated with increased vascularisation,
Autor:
L. S. Kjaerulff, Majken Westergaard, B. J. Hansen, Phil Kearney, Henrik Frydenlund Hansen, L. W. Dalby, H. Oerum, Margit Wissenbach, Thrue Charlotte Albaeck, Miriam Frieden
Publikováno v:
Journal of Clinical Oncology. 24:6610-6610
6610 Background: Bcl-2 protein is a critical regulator of programmed cell death and contributes to apoptosis resistance in many cancers, including chronic lymphocytic leukemia (CLL). The novel RNA antagonist, SPC2996, is a 16-mer oligonucleotide inco