Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Thromboregulation"'
Autor:
Bartley P. Griffith, Peter Hanna, Muhammad Mohiuddin, Susie N. Hong, David Ayares, A. Singh, Corbin E. Goerlich
Publikováno v:
The Journal of Thoracic and Cardiovascular Surgery. 165:e69-e81
Objective Genetically engineered pigs are thought to be an alternative organ source for patients in end-stage heart failure unable to receive a timely allograft. However, cardiac xenografts exhibit growth and diastolic heart failure within 1 month af
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60d693891bc422d31b52fd54b993e4e
https://doi.org/10.1016/j.jtcvs.2021.07.051
https://doi.org/10.1016/j.jtcvs.2021.07.051
Autor:
Priscila Faria-Pinto, Eveline Gomes Vasconcelos, Ismael J. Alves Junior, Mara R.C. Couri, William Castro-Borges, Vinícius R. D. Pereira, Lígia S. da Silveira, Nayara Braga Emidio, Priscila Silva Grijó Farani, Danielle Gomes Marconato, Ademar A. da Silva Filho
Publikováno v:
International journal of biological macromolecules. 164
NTPDases (EC 3.6.1.5) are enzymes belonging to a protein family which have as a common feature the ability to hydrolyze di- and triphosphate nucleotides (ADP and ATP) to monophosphate nucleosides (AMP) in the presence of Ca+2 and Mg+. The potato apyr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e67334647cee5f0bf38d7c96d55919c4
https://pubmed.ncbi.nlm.nih.gov/32663559
https://pubmed.ncbi.nlm.nih.gov/32663559
Autor:
Tatiana Montagner Dalcin Bertoldo, Stephen A. Adefegha, João Felipe Peres Rezer, Daniela F. Passos, Renata da Silva Pereira Saccol, Daniela B.R. Leal, Assis Ecker
Publikováno v:
Microbial Pathogenesis. 114:264-268
HIV replication promotes atherogenesis and participates in the immune response to the virus, thereby influencing the inflammatory profile. These changes may, in turn, contribute to the risk of cardiovascular diseases with involvement of platelets. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ffdf6da140e170463606796e6c492c3
https://doi.org/10.1016/j.micpath.2017.11.045
https://doi.org/10.1016/j.micpath.2017.11.045
Publikováno v:
Animals, ISSN 2076-2615, 2019-10, Vol. 9, No. 10
Archivo Digital UPM
Universidad Politécnica de Madrid
Animals : an Open Access Journal from MDPI
Animals, Vol 9, Iss 10, p 806 (2019)
Archivo Digital UPM
Universidad Politécnica de Madrid
Animals : an Open Access Journal from MDPI
Animals, Vol 9, Iss 10, p 806 (2019)
Simple Summary The nutritional quality of fat for human consumption is usually evaluated in terms of the n-6/n-3 polyunsaturated fatty acid (PUFA) ratio (with optimal values ≤4). Moreover, with respect to animal production, the standard feed is unb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ac585d5f7ffb02096d83f929fa00c05
http://oa.upm.es/63657/
http://oa.upm.es/63657/
Autor:
Kevin J. Quinn, Lars Burdorf, Elizabeth Kang, Agnes M. Azimzadeh, Beth M. French, Richard N. Pierson, David Ayares, Evan A Schwartz, Donald G. Harris, Siamak Dahi, Carol Phelps
Publikováno v:
Xenotransplantation. 22:102-111
Background Genetically modified pigs are a promising potential source of lung xenografts. Ex vivo xenoperfusion is an effective platform for testing the effect of new modifications, but typical experiments are limited by testing of a single genetic i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4364c7d9b22acf07b12a27cc0db04bf
https://doi.org/10.1111/xen.12149
https://doi.org/10.1111/xen.12149
Autor:
Richard N. Pierson, Kevin J. Quinn, Siamak Dahi, Lars Burdorf, Agnes M. Azimzadeh, Donald G. Harris
Publikováno v:
Xenotransplantation. 21:496-506
Xenotransplantation has undergone important progress in controlling initial hyperacute rejection in many pre-clinical models, with some cell, tissue, and organ xenografts advancing toward clinical trials. However, acute injury, driven primarily by in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66494e197a71a887e90d5edf88999b82
https://doi.org/10.1111/xen.12116
https://doi.org/10.1111/xen.12116
Autor:
Lucas T. Gressler, Daniela B.R. Leal, Silvia Gonzalez Monteiro, Mariângela F. de Sá, Ricardo E. Mendes, Pedro H. Doleski, Thirssa H. Grando, Guilherme M. do Carmo, Lenita M. Stefani, Nathieli B. Bottari, Aleksandro Schafer da Silva
Publikováno v:
Molecular and cellular biochemistry. 432(1-2)
Coagulation disorders have been described in Chagas disease with thrombocytopenia as an important event. Several mechanisms may be related to this pathogenesis, such as enzymes of the purinergic system, purine, and receptors involved in the regulatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9b43feb1cbc0b0ab31828da50eaaace
https://pubmed.ncbi.nlm.nih.gov/28285362
https://pubmed.ncbi.nlm.nih.gov/28285362
Autor:
Ryan M. Huttinger, Simon C. Robson, Adam Reynolds, Debra G Wheeler, Richard J. Gumina, Katherine Stanfill, Tatiana Novitskaya, Elena Chepurko, Karen M. Dwyer, Roman Covarrubias, Peter J. Cowan, Zachary M. Huttinger
Objective— Circulating blood cells and endothelial cells express ectonucleoside triphosphate diphosphohydrolase-1 (CD39) and ecto-5′-nucleotidase (CD73). CD39 hydrolyzes extracellular ATP or ADP to AMP. CD73 hydrolyzes AMP to adenosine. The goal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c0e589d3aee316ad2c1f0dabef0487
https://europepmc.org/articles/PMC5206760/
https://europepmc.org/articles/PMC5206760/
Autor:
Viviane do Carmo Gonçalves Souza, Daniela B.R. Leal, Maria Rosa Chitolina Schetinger, Cristiano Bicca Noal, Maria Beatriz Moretto, Juliana Fleck, Luiz Felipe Dias Carli, Karine Bizzi Schlemmer, Jeandre Augusto dos Santos Jaques, Victor C. Pimentel, Claudio A.M. Leal, Margarete Dulce Bagatini
Publikováno v:
Purinergic Signalling. 8:753-762
Chagas disease (CD) is a chronic and endemic illness caused by the parasite Trypanosoma cruzi. Microvascular disturbances play an important role in the progress of the disease. The purinergic signaling system participates in regulatory functions, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85eeacbdd1cc269f7721f373fdee87d8
https://doi.org/10.1007/s11302-012-9322-7
https://doi.org/10.1007/s11302-012-9322-7
Autor:
Mohamed Ezzelarab, Burcin Ekser, Hidetaka Hara, Simon C. Robson, Richard N. Pierson, Leela L. Paris, Carol Phelps, David Ayares, Agnes M. Azimzadeh, Christopher Burlak, David K. C. Cooper, A. Joseph Tector
Publikováno v:
Xenotransplantation. 19:144-158
Barriers to successful lung xenotransplantation appear to be even greater than for other organs. This difficulty may be related to several macro anatomic factors, such as the uniquely fragile lung parenchyma and associated blood supply that results i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90f366a408e6466648a88524c5d0801c
https://doi.org/10.1111/j.1399-3089.2012.00708.x
https://doi.org/10.1111/j.1399-3089.2012.00708.x