Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Thressa D. Smith"'
Autor:
Scott R. Gilbertson, Kathryn A. Cunningham, Thressa D. Smith, Cheryl S. Watson, Patricia K. Seitz, Matthew J. Shashack, Andrew G. McGinnis
Publikováno v:
ACS Chemical Neuroscience. 2:640-644
It is now well accepted that at least some serotonin receptors exist in dimeric and oligmeric forms. The linking of receptor ligands has been shown to have potential in the development of selective agonists and antagonists for traditionally refractiv
Autor:
Terumi Midoro-Horiuti, Patricia K. Seitz, Nataliya N. Bulayeva, Dragoslaca Zivadinovic, Randall M. Goldblum, Thressa D. Smith, Rebecca A. Alyea, Yow Jiun Jeng, Cheryl S. Watson, Celeste C. Finnerty, Kathryn A. Cunningham, Luke Y. Koong, Noelle C. Anastasio
Publikováno v:
Methods in Molecular Biology ISBN: 9781493913459
Methods Mol Biol
Methods Mol Biol
We developed fixed-cell multi-well plate immunoassays that increase the throughput and ease of quantification for questions formerly assessed by immunoblot scanning. The assays make use of the now abundant antibodies designed to recognize receptor su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dc6b04366211760abcdb52ac31ffac7
https://doi.org/10.1007/978-1-4939-1346-6_11
https://doi.org/10.1007/978-1-4939-1346-6_11
Autor:
Michelle M. Adams, John H. Morrison, Yuehua Wang, Michela Gallagher, Peter R. Rapp, Diana Moga, Barry B. Wolfe, Thressa D. Smith
Publikováno v:
The Journal of Comparative Neurology. 432:230-243
Hippocampal N-methyl-D-Aspartate (NMDA) receptors mediate mechanisms of cellular plasticity critical for spatial learning in rats. The present study examined the relationship between spatial learning and NMDA receptor expression in discrete neuronal
Publikováno v:
The Journal of Neuroscience. 20:6587-6593
The present study examined the long-standing concept that changes in hippocampal circuitry contribute to age-related learning impairment. Individual differences in spatial learning were documented in young and aged Long-Evans rats by using a hippocam
Publikováno v:
Synapse. 38:460-470
Fluoxetine (FLU) rapidly enhances extracellular (EC) serotonin (5-HT) in rodent brain, whereas the antidepressant effects of this drug in humans are typically not observed for 2-3 weeks. Thus, the effects of chronic oral FLU administration on neocort
Autor:
Kathryn A. Cunningham, Nicole M. Bremer, Yow-Jiun Jeng, Sarah E. Swinford, Robert G. Fox, Marcy J. Bubar, Marc N. Charendoff, Thressa D. Smith, John W. Craft, Cheryl S. Watson, James M. Briggs, Patricia K. Seitz, Fernanda Laezza, Noelle C. Anastasio, Scott R. Gilbertson, Sonja J. Stutz, Anton Agarkov
Serotonin (5-hydroxytryptamine; 5-HT) signaling through the 5-HT2Creceptor (5-HT2CR) is essential in normal physiology, whereas aberrant 5-HT2CR function is thought to contribute to the pathogenesis of multiple neural disorders. The 5-HT2CR interacts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef95024f8882b1e0b6e6a1f43d436df3
https://europepmc.org/articles/PMC3711763/
https://europepmc.org/articles/PMC3711763/
Publikováno v:
Neurobiology of Aging. 16:161-173
Age-related alterations in the density of cholinergic receptor binding and reuptake sites were examined in discrete forebrain regions of behaviorally tested rats using quantitative autoradiography. Neurochemical changes associated with chronological
Autor:
Patricia K. Seitz, Jia Zhou, Nicole M. Bremer, Chunyong Ding, Kathryn A. Cunningham, Thressa D. Smith, Noelle C. Anastasio
Allosteric modulators of the serotonin (5-HT) 5-HT(2C) receptor (5-HT(2C)R) present a unique drug design strategy to augment the response to endogenous 5-HT in a site- and event-specific manner with great potential as novel central nervous system pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c82fc4765c918fce5f01ecb0c5d96557
https://europepmc.org/articles/PMC3400380/
https://europepmc.org/articles/PMC3400380/
Autor:
Sonja J. Stutz, Thressa D. Smith, Kathryn A. Cunningham, Jia Zhou, Theresa Carbonaro, Christopher Wild, Robert O. Fox, J. Scott Moncrief, Rachel M. Hartley, Chunyong Ding, Gongliang Zhang, Noelle C. Anastasio
Publikováno v:
Drug and Alcohol Dependence. 146:e23
Autor:
Thressa D. Smith, William J. Freed
Publikováno v:
Behavioral and Brain Sciences. 18:58-60
It is often presumed that effects of neural tissue transplants are due to release of neurotransmitter. In many cases, however, effects attributed to transplants may be related to phenomena such as trophic effects mediated by glial cells or even tissu