Zobrazeno 1 - 10
of 854
pro vyhledávání: '"Threadgill P"'
The training of deep and/or convolutional neural networks (DNNs/CNNs) is traditionally done on servers with powerful CPUs and GPUs. Recent efforts have emerged to localize machine learning tasks fully on the edge. This brings advantages in reduced la
Externí odkaz:
http://arxiv.org/abs/2409.09083
In the era of deep learning (DL), convolutional neural networks (CNNs), and large language models (LLMs), machine learning (ML) models are becoming increasingly complex, demanding significant computational resources for both inference and training st
Externí odkaz:
http://arxiv.org/abs/2405.15079
Autor:
Dan Li, Chenhan Zhong, Mengyuan Yang, Li He, Hang Chang, Ning Zhu, Susan E Celniker, David W Threadgill, Antoine M Snijders, Jian-Hua Mao, Ying Yuan
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
ABSTRACTThe insights into interactions between host genetics and gut microbiome (GM) in colorectal tumor susceptibility (CTS) remains lacking. We used Collaborative Cross mouse population model to identify genetic and microbial determinants of Azoxym
Externí odkaz:
https://doaj.org/article/227e8b75c1d146fb911a9277a62d6dff
Autor:
Rebecca L. Bacon, Carolyn L. Hodo, Jing Wu, Shannara Welch, Colette Nickodem, Javier Vinasco, Deborah Threadgill, Stanton B. Gray, Keri N. Norman, Sara D. Lawhon
Publikováno v:
mSphere, Vol 9, Iss 11 (2024)
ABSTRACT Campylobacter jejuni and Campylobacter coli represent the leading causes of bacterial gastroenteritis in humans, and infections can produce post-infectious irritable bowel syndrome (PI-IBS). Rhesus macaques (Macaca mulatta) (RM) are similarl
Externí odkaz:
https://doaj.org/article/f303c24a76e44d2b91d7849d3e9d634f
Autor:
Hui Yang, Xinzhi Wang, Adrián Blanco-Gómez, Li He, Natalia García-Sancha, Roberto Corchado-Cobos, Manuel Jesús Pérez-Baena, Alejandro Jiménez-Navas, Pin Wang, Jamie L. Inman, Antoine M. Snijders, David W. Threadgill, Allan Balmain, Hang Chang, Jesus Perez-Losada, Jian-Hua Mao
Publikováno v:
EBioMedicine, Vol 106, Iss , Pp 105260- (2024)
Summary: Background: Deeper insights into ERBB2-driven cancers are essential to develop new treatment approaches for ERBB2+ breast cancers (BCs). We employed the Collaborative Cross (CC) mouse model to unearth genetic factors underpinning Erbb2-drive
Externí odkaz:
https://doaj.org/article/6fe0af1cc003460fbba638da01b6d216
Autor:
Aravindh Nagarajan, Kristin Scoggin, Jyotsana Gupta, Manuchehr Aminian, L Garry Adams, Michael Kirby, David Threadgill, Helene Andrews-Polymenis
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011229 (2024)
Staphylococcus aureus (S. aureus) is an opportunistic pathogen causing diseases ranging from mild skin infections to life threatening conditions, including endocarditis, pneumonia, and sepsis. To identify host genes modulating this host-pathogen inte
Externí odkaz:
https://doaj.org/article/50315e75f7be410b9174f63ab5c73feb
Autor:
Anna C. Salvador, M. Nazmul Huda, Danny Arends, Ahmed M. Elsaadi, C. Anthony Gacasan, Gudrun A. Brockmann, William Valdar, Brian J. Bennett, David W. Threadgill
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-21 (2023)
Abstract Background The gut microbiota is modulated by a combination of diet, host genetics, and sex effects. The magnitude of these effects and interactions among them is important to understanding inter-individual variability in gut microbiota. In
Externí odkaz:
https://doaj.org/article/b402e2ffdfaf458f8c7d6ff0c082a0a0
Autor:
Aravindh Nagarajan, Kristin Scoggin, Jyotsana Gupta, David W. Threadgill, Helene L. Andrews-Polymenis
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-16 (2023)
Abstract Background The human gut microbiota is a complex community comprised of trillions of bacteria and is critical for the digestion and absorption of nutrients. Bacterial communities of the intestinal microbiota influence the development of seve
Externí odkaz:
https://doaj.org/article/ceb9945b653e4dedbefee43389dd5a48
Autor:
Hongying Wang, Zheng Shen, Chia-Shan Wu, Pengfei Ji, Ji Yeon Noh, Cédric G. Geoffroy, Sunja Kim, David Threadgill, Jianrong Li, Yu Zhou, Xiaoqiu Xiao, Hui Zheng, Yuxiang Sun
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Obesity is associated with chronic inflammation in the central nervous system (CNS), and neuroinflammation has been shown to have detrimental effects on mood and cognition. The growth hormone secretagogue receptor (GHSR), the biologically relevant re
Externí odkaz:
https://doaj.org/article/8fec41a6174d491db5c879b086c00aa4
Autor:
Da Mi Kim, Jong Han Lee, Quan Pan, Hye Won Han, Zheng Shen, Sahar Eshghjoo, Chia-Shan Wu, Wanbao Yang, Ji Yeon Noh, David W. Threadgill, Shaodong Guo, Gus Wright, Robert Alaniz, Yuxiang Sun
Publikováno v:
Molecular Metabolism, Vol 79, Iss , Pp 101852- (2024)
Objective: Obesity-associated chronic inflammation, aka meta-inflammation, is a key pathogenic driver for obesity-associated comorbidity. Growth hormone secretagogue receptor (GHSR) is known to mediate the effects of nutrient-sensing hormone ghrelin
Externí odkaz:
https://doaj.org/article/6f8f999d1d354a3685b42a6470e37fe0