Malaria and obesity: obese mice are resistant to cerebral malaria

Autor: Lombard Marie-Noëlle, Thouvenot Catherine, Depoix Delphine, Bourgouin Catherine, Robert Vincent, Grellier Philippe

Publikováno v: Malaria Journal, Vol 7, Iss 1, p 81 (2008)

Summary Background The relationship between malaria and obesity are largely unknown. This is partly due to the fact that malaria occurs mainly in tropical areas where, until recently, obesity was not prevalent. It now appears, however, that obesity i

Externí odkaz: https://doaj.org/article/ce26e25e71524c17b718b56b5f2f52b4

SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance

Autor: Robinot, Rémy, Hubert, Mathieu, de Melo, Guilherme Dias, Lazarini, Françoise, Bruel, Timothée, Smith, Nikaïa, Levallois, Sylvain, Larrous, Florence, Fernandes, Julien, Gellenoncourt, Stacy, Rigaud, Stéphane, Gorgette, Olivier, Thouvenot, Catherine, Trébeau, Céline, Mallet, Adeline, Duménil, Guillaume, Gobaa, Samy, Etournay, Raphaël, Lledo, Pierre-Marie, Lecuit, Marc, Bourhy, Hervé, Duffy, Darragh, Michel, Vincent, Schwartz, Olivier, Chakrabarti, Lisa

Publikováno v: Nature Communications
Nature Communications, Nature Publishing Group, 2021, 12 (1), pp.4354. ⟨10.1038/s41467-021-24521-x⟩
Nature Communications, 2021, 12 (1), pp.4354. ⟨10.1038/s41467-021-24521-x⟩
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)

Understanding how SARS-CoV-2 spreads within the respiratory tract is important to define the parameters controlling the severity of COVID-19. Here we examine the functional and structural consequences of SARS-CoV-2 infection in a reconstructed human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1b12422ca9e4b330a8b8cbf638580505
https://hal-pasteur.archives-ouvertes.fr/pasteur-03319522/document

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SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance.

Autor: Robinot R; Virus & Immunity Unit, Department of Virology, Institut Pasteur, Paris, France.; UMR 3569 CNRS, Paris, France., Hubert M; Virus & Immunity Unit, Department of Virology, Institut Pasteur, Paris, France.; UMR 3569 CNRS, Paris, France., de Melo GD; Lyssavirus Epidemiology and Neuropathology Unit, Institut Pasteur, Paris, France., Lazarini F; Perception and Memory Unit, Institut Pasteur, Paris, France.; UMR 3571 CNRS, Paris, France., Bruel T; Virus & Immunity Unit, Department of Virology, Institut Pasteur, Paris, France.; UMR 3569 CNRS, Paris, France., Smith N; Translational Immunology Lab, Department of Immunology, Institut Pasteur, Paris, France., Levallois S; Biology of Infection Unit, Institut Pasteur, Paris, France.; INSERM U1117, Paris, France., Larrous F; Lyssavirus Epidemiology and Neuropathology Unit, Institut Pasteur, Paris, France., Fernandes J; UtechS Photonics BioImaging, C2RT, Institut Pasteur, Paris, France., Gellenoncourt S; Virus & Immunity Unit, Department of Virology, Institut Pasteur, Paris, France.; UMR 3569 CNRS, Paris, France., Rigaud S; Image Analysis Hub, C2RT, Institut Pasteur, Paris, France., Gorgette O; UtechS Ultrastructural BioImaging UBI, C2RT, Institut Pasteur, Paris, France., Thouvenot C; UtechS Ultrastructural BioImaging UBI, C2RT, Institut Pasteur, Paris, France., Trébeau C; Institut de l'Audition, Institut Pasteur, INSERM, Paris, France., Mallet A; UtechS Ultrastructural BioImaging UBI, C2RT, Institut Pasteur, Paris, France., Duménil G; UtechS Ultrastructural BioImaging UBI, C2RT, Institut Pasteur, Paris, France., Gobaa S; Biomaterials and Microfluidics Core Facility, Institut Pasteur, Paris, France., Etournay R; Institut de l'Audition, Institut Pasteur, INSERM, Paris, France., Lledo PM; Perception and Memory Unit, Institut Pasteur, Paris, France.; UMR 3571 CNRS, Paris, France., Lecuit M; Biology of Infection Unit, Institut Pasteur, Paris, France.; INSERM U1117, Paris, France.; Université de Paris, Necker-Enfants Malades University Hospital, Division of Infectious Diseases and Tropical Medicine, APHP, Institut Imagine, Paris, France., Bourhy H; Lyssavirus Epidemiology and Neuropathology Unit, Institut Pasteur, Paris, France., Duffy D; Translational Immunology Lab, Department of Immunology, Institut Pasteur, Paris, France., Michel V; Institut de l'Audition, Institut Pasteur, INSERM, Paris, France. vincent.michel@pasteur.fr., Schwartz O; Virus & Immunity Unit, Department of Virology, Institut Pasteur, Paris, France. olivier.schwartz@pasteur.fr.; UMR 3569 CNRS, Paris, France. olivier.schwartz@pasteur.fr.; Vaccine Research Institute, Créteil, France. olivier.schwartz@pasteur.fr., Chakrabarti LA; Virus & Immunity Unit, Department of Virology, Institut Pasteur, Paris, France. chakra@pasteur.fr.; UMR 3569 CNRS, Paris, France. chakra@pasteur.fr.

Publikováno v: Nature communications [Nat Commun] 2021 Jul 16; Vol. 12 (1), pp. 4354. Date of Electronic Publication: 2021 Jul 16.