Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Thorsten Wöhl"'
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 6, Pp 100220- (2022)
The localization of many membrane proteins within cholesterol- and sphingolipid-containing microdomains is essential for proper cell signaling and function. These membrane domains, however, are too small and dynamic to be recorded, even with modern s
Externí odkaz:
https://doaj.org/article/1422a6873f534c73a0a57f266b092ae1
Autor:
Sapthaswaran Veerapathiran, Cathleen Teh, Shiwen Zhu, Indira Kartigayen, Vladimir Korzh, Paul T Matsudaira, Thorsten Wohland
Publikováno v:
eLife, Vol 9 (2020)
Wnt3 proteins are lipidated and glycosylated signaling molecules that play an important role in zebrafish neural patterning and brain development. However, the transport mechanism of lipid-modified Wnts through the hydrophilic extracellular environme
Externí odkaz:
https://doaj.org/article/1e66ade74e3f413c9bb8ff67f3c8a3d5
Publikováno v:
eLife, Vol 5 (2016)
The correct distribution and activity of secreted signaling proteins called morphogens is required for many developmental processes. Nodal morphogens play critical roles in embryonic axis formation in many organisms. Models proposed to generate the N
Externí odkaz:
https://doaj.org/article/5b49b2a9c6bd4c79beb9dd3a3253d7df
Autor:
Jagadish Sankaran, Thorsten Wohland
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Fluorescence correlation spectroscopy (FCS) is a single molecule sensitive tool for the quantitative measurement of biomolecular dynamics and interactions. Improvements in biology, computation, and detection technology enable real-time FCS e
Externí odkaz:
https://doaj.org/article/af350945632d4420b7dfa373da5f138f
Autor:
Wolfgang Hoeppner, Dieter Engelhardt, Hendrik Jähnig, Michael M. Ritter, Fritz Spelsberg, Hiltrud Brauch, Thorsten Wöhl
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 82:4101-4104
Pheochromocytoma is a tumor that may occur sporadically or may be a manifestation of a hereditary disease, such as von Hippel-Lindau disease (VHL) and multiple endocrine neoplasia (MEN) type 2. As patients with VHL or MEN type 2 are at risk to develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48dc4730fd138006e40e25030268594c
https://doi.org/10.1210/jcem.82.12.4454
https://doi.org/10.1210/jcem.82.12.4454
Publikováno v:
Molecular and General Genetics MGG. :305-311
In Saccharomyces cerevisiae, hypusine-containing proteins are encoded by two closely related genes, HYP1 and HYP2, which are regulated reciprocally by oxygen and heme. We have purified the aerobically expressed hypusine-containing proteins from yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::180ece54072c754cf531a8f78349db80
https://doi.org/10.1007/bf00284682
https://doi.org/10.1007/bf00284682
Autor:
Jagadish Sankaran, Harikrushnan Balasubramanian, Wai Hoh Tang, Xue Wen Ng, Adrian Röllin, Thorsten Wohland
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Super-resolution microscopy and single molecule fluorescence spectroscopy require optimisation of the temporal or spatial resolution, which are usually mutually exclusive. Here the authors report a GPU-supported, camera-based strategy to achieve high
Externí odkaz:
https://doaj.org/article/5265c92c25e340d3a20a131b38551845
Publikováno v:
The Journal of clinical endocrinology and metabolism. 87(11)
Von Hippel-Lindau disease (VHL) is a multitumor syndrome that develops on the basis of germline mutations in the VHL tumor suppressor gene. Genotype-phenotype correlations have helped to stratify the disease into VHL type 1 (without pheochromocytoma)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8c6e15e4c3d249413950c407d80917
https://pubmed.ncbi.nlm.nih.gov/12414898
https://pubmed.ncbi.nlm.nih.gov/12414898
Publikováno v:
Journal of Lipid Research, Vol 61, Iss 2, Pp 252-266 (2020)
A fundamental feature of the eukaryotic cell membrane is the asymmetric arrangement of lipids in its two leaflets. A cell invests significant energy to maintain this asymmetry and uses it to regulate important biological processes, such as apoptosis
Externí odkaz:
https://doaj.org/article/52226c780bdf4dacb5f546ceb3ef4b0e
Autor:
Karl Koettnitz, Michèle Himmelspach, Friedrich Lottspeich, Martin Oft, Marika Dobrovnik, Michael Schebesta, Alexandra Pacher, Herbert Jaksche, Joachim Hauber, Dorian Bevec, Robert Csonga, Thorsten Wöhl
Publikováno v:
Science (New York, N.Y.). 271(5257)
Eukaryotic initiation factor 5A (eIF-5A) is a cellular cofactor required for the function of the human immunodeficiency virus type-1 (HIV-1) Rev trans-activator protein. The majority of a set of eIF-5A mutants did not support growth of yeast cells ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f4f1f06046f6103ebaca14f9de77e32
https://pubmed.ncbi.nlm.nih.gov/8596953
https://pubmed.ncbi.nlm.nih.gov/8596953