Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Thorsten Simon"'
Autor:
Costanza Chiapponi, Milan Janis Michael Hartmann, Boris Decarolis, Thorsten Simon, Christiane Josephine Bruns, Michael Faust, Anne Maria Schultheis, Matthias Schmidt, Hakan Alakus
Publikováno v:
JCRPE, Vol 15, Iss 3, Pp 257-263 (2023)
INTRODUCTION: Differentiated thyroid cancer (DTC) in adolescents rare but with a favorable outcome, despite higher rates of cervical lymph node and pulmonary metastasis compared to adults. The aim of this study was to critically evaluate treatment of
Externí odkaz:
https://doaj.org/article/0bd853828ec5411cb6fabfce3268021c
Autor:
Danny Jazmati, Barbara Hero, Theresa M. Thole.-Kliesch, Julien Merta, Hedwig E. Deubzer, Christian Bäumer, Feline Heinzelmann, Stefanie Schulze Schleithoff, Friederike Koerber, Angelika Eggert, Rudolf Schwarz, Thorsten Simon, Beate Timmermann
Publikováno v:
Current Oncology, Vol 29, Iss 11, Pp 8222-8234 (2022)
Background: Despite an intensive multimodal treatment approach, approximately 50% of high-risk (HR) neuroblastoma (NB) patients experience progression. Despite the advances in targeted therapy, high-dose chemotherapy, and other systemic treatment opt
Externí odkaz:
https://doaj.org/article/2eda78254f904a3a9f743eb2d70d7c1b
Autor:
Alina Meeser, Christoph Bartenhagen, Lisa Werr, Anna-Maria Hellmann, Yvonne Kahlert, Nadine Hemstedt, Peter Nürnberg, Janine Altmüller, Sandra Ackermann, Barbara Hero, Thorsten Simon, Martin Peifer, Matthias Fischer, Carolina Rosswog
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Background Telomere maintenance mechanisms (TMM) are a hallmark of high-risk neuroblastoma, and are conferred by activation of telomerase or alternative lengthening of telomeres (ALT). However, detection of TMM is not yet part of the clinica
Externí odkaz:
https://doaj.org/article/04d7590f1e6a4f35ba877b94d65b186b
Autor:
Tim Flaadt, Martin Ebinger, Malin Schreiber, Ruth L. Ladenstein, Thorsten Simon, Holger N. Lode, Barbara Hero, Martin U. Schuhmann, Jürgen Schäfer, Frank Paulsen, Beate Timmermann, Angelika Eggert, Peter Lang
Publikováno v:
Journal of Clinical Medicine, Vol 12, Iss 19, p 6196 (2023)
Despite highly intensive multimodality treatment regimens, the prognosis of patients with high-risk neuroblastoma (HRNB) and central nervous system (CNS) relapse remains poor. We retrospectively reviewed data from 13 patients with HRNB and CNS relaps
Externí odkaz:
https://doaj.org/article/251c862a9f1f4a99abd3c436900754dc
Publikováno v:
Journal of Statistical Software, Vol 100, Pp 1-53 (2021)
Over the last decades, the challenges in applied regression and in predictive modeling have been changing considerably: (1) More flexible regression model specifications are needed as data sizes and available information are steadily increasing, cons
Externí odkaz:
https://doaj.org/article/f73117aebc464fbf8efc06d34ba7ed46
Autor:
Stefania Sorrentino, Shifra Ash, Riccardo Haupt, Dominique Plantaz, Isabelle Schiff, Barbara Hero, Thorsten Simon, Denis Kachanov, Tatyana Shamanskaya, Katheljine Kraal, Annemieke Littooij, Alexsandra Wieczoreck, Walentyna Balwierz, Geneviève Laureys, Catherine Trager, Fiammetta Sertorio, Giovanni Erminio, Martina Fragola, Maja Beck Popovic, Bruno De Bernardi, Toby Trahair
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
IntroductionBetween 5 and 15% of children with neuroblastoma (NB) present with or develop spinal canal invasion (SCI). The majority of these children have symptoms of epidural compression of spinal cord and/or spinal nerves. Treatment of NB-SCI is co
Externí odkaz:
https://doaj.org/article/8a44d9405a7c4ce889fd9b3a565c092b
Autor:
Michaela Kuhlen, Christina Pamporaki, Marina Kunstreich, Stefan A. Wudy, Michaela F. Hartmann, Mirko Peitzsch, Christian Vokuhl, Guido Seitz, Michael C. Kreissl, Thorsten Simon, Barbara Hero, Michael C. Frühwald, Peter Vorwerk, Antje Redlich
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
In children and adolescents, neuroblastoma (NBL), pheochromocytoma (PCC), and adrenocortical tumors (ACT) can arise from the adrenal gland. It may be difficult to distinguish between these three entities including associated extra-adrenal tumors (par
Externí odkaz:
https://doaj.org/article/ac8972243d7a4ddfbb8232006990456e
Autor:
Diana Veiga-Canuto, Leonor Cerdà-Alberich, Ana Jiménez-Pastor, José Miguel Carot Sierra, Armando Gomis-Maya, Cinta Sangüesa-Nebot, Matías Fernández-Patón, Blanca Martínez de las Heras, Sabine Taschner-Mandl, Vanessa Düster, Ulrike Pötschger, Thorsten Simon, Emanuele Neri, Ángel Alberich-Bayarri, Adela Cañete, Barbara Hero, Ruth Ladenstein, Luis Martí-Bonmatí
Publikováno v:
Cancers, Vol 15, Iss 5, p 1622 (2023)
Objectives. To externally validate and assess the accuracy of a previously trained fully automatic nnU-Net CNN algorithm to identify and segment primary neuroblastoma tumors in MR images in a large children cohort. Methods. An international multicent
Externí odkaz:
https://doaj.org/article/c554c1da21264df2be46c417ffc31d0d
Autor:
Michael Abele, Lisa Grabner, Tabea Blessing, Andreas Block, Abbas Agaimy, Christian Kratz, Thorsten Simon, Gabriele Calaminus, Sabine Heine, Selim Corbacioglu, Holger Christiansen, Dominik T. Schneider, Ines B. Brecht
Publikováno v:
Cancers, Vol 15, Iss 1, p 317 (2023)
(1) Background: Gastric carcinoma is an exceptionally rare tumor in childhood. Little is known about the etiology, epidemiology, and clinical features of pediatric gastric carcinomas. This analysis aimed to fill this gap by increasing knowledge about
Externí odkaz:
https://doaj.org/article/768616db20b14556ab1d589d871e4d49
Autor:
Oliver Zolk, Annika von dem Knesebeck, Norbert Graf, Thorsten Simon, Barbara Hero, Hashim Abdul-Khaliq, Mohamed Abd El Rahman, Claudia Spix, Benjamin Mayer, Susanne Elsner, Judith Gebauer, Thorsten Langer
Publikováno v:
JMIR Research Protocols, Vol 11, Iss 2, p e27898 (2022)
BackgroundIn childhood cancer survivors (survival of 5 years or more after diagnosis), cardiac toxicity is the most common nonmalignant cause of death attributed to treatment-related consequences. Identifying patients at risk of developing late cardi
Externí odkaz:
https://doaj.org/article/a6a5bceb52ee41719f45b64efa932c84