Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Thorsten Merkofer"'
Publikováno v:
Tetrahedron Letters. 40:6009-6012
Mutagenesis of Tyr420 to Ala in the catalytic cavity of squalene-hopene cyclase of Alicyclobacillus acidocaldarius resulted in an altered product spectrum. Besides hopene and diplopterol, this mutant produced significant amounts of the bicyclic α- a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7571750a71cfbc192367dcf1d35ddbc5
https://doi.org/10.1016/s0040-4039(99)01248-4
https://doi.org/10.1016/s0040-4039(99)01248-4
Autor:
Michel Rohmer, Karl Ulrich Wendt, Karl Poralla, Thorsten Merkofer, Catherine Pale-Grosdemange
Publikováno v:
Tetrahedron Letters. 40:2121-2124
Amino acid residues lining the catalytic cavity of squalene-hopene cyclase of Alicyclobacillus acidocaldarius have been mutated. Alterations of His451 to Ala and Trp489 to Ala resulted in reduced enzymatic activity, while the product patterns were id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1576bb1621f6f34be9fdec10882ccca
https://doi.org/10.1016/s0040-4039(99)00145-8
https://doi.org/10.1016/s0040-4039(99)00145-8
Publikováno v:
Journal of Endotoxin Research. 3:345-352
The double bond of dodecenoic acid in the endotoxin-antagonistically acting lipid A of Rhodobacter capsulatus, strains 37b4 and St Louis, was found to have cis-configuration. The position of the double bond was ω7. The mono-unsaturated fatty acids o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda65225ea7331c2254edfdabf0886af
https://doi.org/10.1177/096805199600300409
https://doi.org/10.1177/096805199600300409