Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Thorsten Kirsch"'
Autor:
Sher Bahadur Poudel, Ryan R. Ruff, Gozde Yildirim, Richard A. Miller, David E. Harrison, Randy Strong, Thorsten Kirsch, Shoshana Yakar
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-14 (2024)
Abstract Background Primary osteoarthritis (OA) occurs without identifiable underlying causes such as previous injuries or specific medical conditions. Age is a major contributing factor to OA, and as one ages, various joint tissues undergo gradual c
Externí odkaz:
https://doaj.org/article/d256ca38541c4e61b75a42aa0e812485
Autor:
Fenglin Zhang, Andrew J. Clair, John F. Dankert, You Jin Lee, Kirk A. Campbell, Thorsten Kirsch
Publikováno v:
Cells, Vol 13, Iss 9, p 757 (2024)
Background: Since cytokine receptor-like factor 1 (CRLF1) has been implicated in tissue regeneration, we hypothesized that CRLF1 released by mesenchymal stem cells can promote the repair of osteochondral defects. Methods: The degree of a femoral oste
Externí odkaz:
https://doaj.org/article/c983eb2a20f84417a3ad0a23ce746362
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13, p 7058 (2021)
Mesenchymal stem cells (MSCs) obtained from various sources, including bone marrow, have been proposed as a therapeutic strategy for the improvement of tissue repair/regeneration, including the repair of cartilage defects or lesions. Often the highly
Externí odkaz:
https://doaj.org/article/3df269bfbe124df68b15a3d409ade4c5
Autor:
Takeshi Minashima, Thorsten Kirsch
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197690 (2018)
Annexin A6 (AnxA6) is expressed in articular chondrocytes at levels higher than in other mesenchymal cell types. However, the role of AnxA6 in articular chondrocytes is not known. Here we show that complete lack of AnxA6 functions resulted in increas
Externí odkaz:
https://doaj.org/article/44ed8dffbd434a4ab8d9e1275d1ffdf6
Autor:
Sher Bahadur Poudel, Ryan R. Ruff, Gozde Yildirim, Manisha Dixit, Benoit Michot, Jennifer L. Gibbs, Silvana Duran Ortiz, John J. Kopchick, Thorsten Kirsch, Shoshana Yakar
Publikováno v:
The American Journal of Pathology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4eb6020e66f21f1a7640419b2f58f25b
https://doi.org/10.1016/j.ajpath.2023.02.010
https://doi.org/10.1016/j.ajpath.2023.02.010
Autor:
Shoshana Yakar, Ikeno Yuji, Jose Cordoba-Chacon, Manuel D. Gahete, Rhonda D. Kineman, Manisha Dixit, Gozde Yildirim, Sher Bahadur Poudel, Thorsten Kirsch
Publikováno v:
Aging Cell
Osteoarthritis (OA), the most prevalent joint disease, is a major cause of disability worldwide. Growth hormone (GH) has been suggested to play significant roles in maintaining articular chondrocyte function and ultimately articular cartilage (AC) ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f0d0985faa7cfaf986b17c5bed77d89
https://doi.org/10.1111/acel.13427
https://doi.org/10.1111/acel.13427
Publikováno v:
J Orthop Res
The purpose of this investigation was to determine the role of extracellular vesicles (EVs), released from articular chondrocytes in a physiological or pathological state, in cell-cell communication with other articular chondrocytes or chondrocyte pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e674d1b7920d651dc112e593ce810b
https://doi.org/10.1002/jor.24525
https://doi.org/10.1002/jor.24525
Autor:
Mary K. Cowman, Xiayun Huang, Yuhong Fu, Jai Rathore, Jemma Villavieja, Claire Shortt, Tatini Rakshit, Shivani Arora, Gyu Ik Jung, Thorsten Kirsch
Publikováno v:
Inflammation
Hyaluronan (HA) fragments have been proposed to elicit defensive or pro-inflammatory responses in many cell types. For articular chondrocytes in an inflammatory environment, studies have failed to reach consensus on the endogenous production or effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f274d157297e4632699d9a9fb35dcd92
http://europepmc.org/articles/PMC6719336
http://europepmc.org/articles/PMC6719336
Publikováno v:
TP62. TP062 TERRORISM AND INHALATIONAL DISASTERS: WORLD TRADE CENTER AND BEYOND.
RATIONALE Coronavirus Disease-2019(COVID-19), caused by the severe acute respiratory syndrome coronavirus-2(SARS-CoV-2), causes multi-organ failure and death. Metabolic syndrome(MetSyn) characteristics are also risks for COVID-19. The Receptor for Ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::777d2b5d86188e373a4e7b18aec45cb4
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3065
https://doi.org/10.1164/ajrccm-conference.2021.203.1_meetingabstracts.a3065
Autor:
Amparo Ruiz, José G. Raya, Thorsten Kirsch, Alejandra Duarte, Elisa Ramos, Dalibel Bravo, Leonard G. Luyt, Chongda Zhang, Mark Milne, Mary K. Cowman
Publikováno v:
Osteoarthritis Cartilage
OBJECTIVE. One driving factor in the progression to posttraumatic osteoarthritis (PTOA) is the perpetuation of the inflammatory response to injury into chronic inflammation. Molecular imaging offers many opportunities to complement the sensitivity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0978ad13caf293be4a16e8dc6af85c02
https://pubmed.ncbi.nlm.nih.gov/34774790
https://pubmed.ncbi.nlm.nih.gov/34774790