Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Thorsten, Vetter"'
Autor:
Ieuan Clay, Nele Peerenboom, Dana E Connors, Steven Bourke, Alison Keogh, Katarzyna Wac, Tova Gur-Arie, Justin Baker, Christopher Bull, Andrea Cereatti, Francesca Cormack, Damien Eggenspieler, Luca Foschini, Raluca Ganea, Peter MA Groenen, Nicole Gusset, Elena Izmailova, Christoph M Kanzler, Lada Leyens, Kate Lyden, Arne Mueller, Julian Nam, Wan-Fai Ng, David Nobbs, Foteini Orfaniotou, Thanneer Malai Perumal, Wojciech Piwko, Anja Ries, Alf Scotland, Nick Taptiklis, John Torous, Beatrix Vereijken, Shuai Xu, Laurenz Baltzer, Thorsten Vetter, Jörg Goldhahn, Steven C Hoffmann
Publikováno v:
Digital Biomarkers, Vol 7, Iss 1, Pp 28-44 (2023)
Background: Digital measures offer an unparalleled opportunity to create a more holistic picture of how people who are patients behave in their real-world environments, thereby establishing a better connection between patients, caregivers, and the cl
Externí odkaz:
https://doaj.org/article/8bfc22bc80e3453e82490bb1a5d5e323
Autor:
Seya Colloud, Thomas Metcalfe, Scott Askin, Shibeshih Belachew, Johannes Ammann, Ernst Bos, Timothy Kilchenmann, Paul Strijbos, Damien Eggenspieler, Laurent Servais, Chloé Garay, Athanasios Konstantakopoulos, Armin Ritzhaupt, Thorsten Vetter, Claudia Vincenzi, Francesca Cerreta
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-11 (2023)
Abstract Digital health technology tools (DHTTs) present real opportunities for accelerating innovation, improving patient care, reducing clinical trial duration and minimising risk in medicines development. This review is comprised of four case stud
Externí odkaz:
https://doaj.org/article/96809dd19189420b9cbff01bd079ea62
Autor:
Natalie M. Hendrikse, Jordi Llinares Garcia, Thorsten Vetter, Anthony J. Humphreys, Falk Ehmann
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Biomarkers are important tools in medicines development and clinical practice. Besides their use in clinical trials, such as for enrichment of patients, monitoring safety or response to treatment, biomarkers are a cornerstone of precision medicine. T
Externí odkaz:
https://doaj.org/article/d3d43f8f51b74d96af863ee4ce55247a
Autor:
Elisabeth Bakker, Peter G. M. Mol, João Nabais, Thorsten Vetter, Matthias Kretzler, John J. Nolan, Gert Mayer, Anna K. Sundgren, Hiddo J. L. Heerspink, Anja Schiel, Sieta T. de Vries, Maria F. Gomez, Friedrich Schulze, Dick de Zeeuw, Michelle J. Pena, for the BEAt-DKD Consortium
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Aim: This study aimed to identify from different stakeholders the benefits and obstacles of implementing precision medicine in diabetic kidney disease (DKD) and to build consensus about a way forward in order to treat, prevent, or even reverse this d
Externí odkaz:
https://doaj.org/article/f77b8bd284ea47e89bad5a6ed9657caf
Autor:
Elisabeth Bakker, Natalie M. Hendrikse, Falk Ehmann, Daniëlla S. van der Meer, Jordi Llinares Garcia, Thorsten Vetter, Viktoriia Starokozhko, Peter G.M. Mol
Publikováno v:
Clinical Pharmacology & Therapeutics, 112(1), 69-80. Nature Publishing Group
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics
Regulatory qualification of biomarkers facilitates their harmonized use across drug developers, enabling more personalized medicine. This study reviews various aspects of the European Medicines Agency's (EMA's) biomarker qualification procedure, incl
Publikováno v:
Therapeutic Innovation & Regulatory Science.
As medicines development continues towards a globalized approach, both the pharmaceutical industry and regulatory agencies increasingly seek opportunities to proactively engage early in product development. The parallel scientific advice program shar
Autor:
Camilla S. Hanson, Jonathan C. Craig, Charlotte Logeman, Aditi Sinha, Allison Dart, Allison A. Eddy, Chandana Guha, Debbie S. Gipson, Detlef Bockenhauer, Hui-Kim Yap, Jaap Groothoff, Michael Zappitelli, Nicholas J.A. Webb, Stephen I. Alexander, Susan L. Furth, Susan Samuel, Alicia Neu, Andrea K. Viecelli, Angela Ju, Ankit Sharma, Eric H. Au, Hailey Desmond, Jenny I. Shen, Karine E. Manera, Karolis Azukaitis, Louese Dunn, Simon A. Carter, Talia Gutman, Yeoungjee Cho, Amanda Walker, Anna Francis, Cheryl Sanchez-Kazi, Joshua Kausman, Meghan Pearl, Nadine Benador, Shobha Sahney, Allison Tong, Abhjit Guha, Adaobi Solarin, Adriana Platona, Alexander Hamilton, Alice Woods-Barnard, Allison Eddy, Alyssa Karathanas, Amanda Baumgart, Amelia Fielding, Amelia LePage, Amelie Bernier-Jean, Amy Kelly, Ana Teixeira, Andrea Viecelli, Andrea Matus, Andrew Narva, Angela Yee-Moon Wang, Anna Fielding, Anthony Meza, Aria Fielding, Armando Teixeira-Pinto, Arvind Bagga, Augustina Jankauskienė, Ayano Kelly, Barbara Gillespie, Benedicte Sautenet, Beth Vogt, Bethany Foster, Bradley Warady, Bradley Dixon, Braden Manns, Brenda Hemmelgarn, Brittney Bscardark, Brooklyn Romeo, Camilla Hanson, Carlos Meza, Carter Brockett, Chanel Prestidge, Charmaine Green, Christy Perkins, Claus Peter Schmitt, Craig Fielding, Craig Settee, Daniel Sumpton, Daniel Meza, Darien Karathanas, David Harris, David Wheeler, David Hooper, Debbie Gipson, Denis Geary, Dieter Haffner, Djalila Mekahli, Dorota Drozdz, Ed Romeo, Elaine Ku, Elaine Urbina, Elena Levtchenko, Elena Balovlenkov, Elisabeth Hodson, Emily Morales, Emma O'Lone, Emma Machuca, Emmah Carlton, Eric Au, Erin Olver, Estefania Morales, Fatima Mirza, Fiona Mackie, Francesca Tentori, Franz Schaefer, Gail Higgins, Georges Deschenes, Georgia Plunkett, Gerilyn Yoder, Germaine Wong, Giselle Morales, Greg Germino, Hayley Perkins, Harrison Mitchell-Smith, Helen Coolican, Hong Xu, Ifeoma Anochie, Il-Soo Ha, Ira Davis, Isaac Liu, Israel Samaniego, Jaime Machuca, James Machuca, Jasmijn Kerklaan, Jeff Brockett, Jenna Norton, Jenny Shen, Jens Goebel, Jia Rao, Jimmy Machuca, Jo Mitchell-Smith, Jo Watson, John Gill, Jonathan Craig, Joseph T. Flynn, Joshua Samuels, Justine Bacchetta, Kaleb Yoder, Karine Manera, Katherine Twombley, Kelly-Ann McMichael, Kenji Ishikura, Kennedy Romeo, Kevin Settee, Kim Linh Van, Lachlan McMichael, Lany Trinh, Larry Greenbaum, Laura Sanchez, Leo Fielding, Lesley Rees, Leslie Lippincott, Levi Mejia-Saldivar, Lidia Saldivar, Lisa Guay-Woodford, Lizett Samaniego, Lorraine Hamiwka, Lorraine Bell, Lucinda Barry, Luke Macauley, Luke Holmes, Madelynn Karathanas, Madison Mitchell-Smith, Mandy Walker, Manuel Benavides, Marcello Tonelli, Maria Ferris, Marina Vivarelli, Mark Wolfenden, Martin Howell, Martin Christian, Martin Schreiber, Marva Moxey-Mims, Mary Leonard, Matthew Karathanas, Melissa Natatmadja, Melissa Brockett, Melvin Bonilla-Felix, Meredith Atkinson, Michel Baum, Michelle Rheault, Mignon McCulloch, Mina Matsuda-Abedini, Mini Michael, Mohammad Khan, Mohammad Salih, Mycah Ann Carlton, Ngairre Plunkett, Nick Webb, Nicki Scholes-Robertson, Nicolas Larkins, Nicole Evangelidis, Nigel Yoder, Norma Meza, Paige Olver, Paiyton Carlton, Patrick Brophy, Peter Tugwell, Pierre Cochat, Rajnish Mehrotra, Raphael Wolfenden, Rasheed Gbadegesin, Raymond Benavides, Rebecca Johnson, Ricardo Morales, Richard McGee, Richard Fish, Robert Gardos, Roberto Pecoits-Filho, Rocio Vargas, Rodolfo Saldivar, Rosanna Coppo, Rukshana Shroff, Rupesh Raina, Sajeda Youssouf, Sally Crowe, Samaya Anumudu, Samuel Chan, Sarah Baldacchino, Scott Wenderfer, Sebastian Wolfenden, Selah Carlton, Shanna Sutton, Shannon Murphy, Sharon Teo, Sheyma Salih, Silas Carlton, Simon Carter, Simone Pearson, Simra Khan, Skyla Wilson, Sonia Sharma, Stephen Alexander, Stephen Marks, Stephen Cornish, Stuart Goldstein, Susan Furth, Susan Mendley, Susan Lippincott, Symone Charles, Terri Mitchell-Smith, Tess Harris, Thorsten Vetter, Tiffany Carlton, Timothy Carlton, Uwe Querfeld, Valeria Saglimbene, Virginia Charles, Wim van Biesen, Wolfgang Winkelmayer, Yenissey Machuca, Yusuf Salih, Yo Han Anh, Zachary Perkins, Zeynab Salih
Publikováno v:
Kidney international, 98(3), 553-565. Nature Publishing Group
Trials in children with chronic kidney disease do not consistently report outcomes that are critically important to patients and caregivers. This can diminish the relevance and reliability of evidence for decision making, limiting the implementation
Autor:
Andrew Thomson, Hrefna Gudmundsdottir, Romaldas Mačiulaitis, Norbert Benda, Frank Holtkamp, Thorsten Vetter
Publikováno v:
American Journal of Kidney Diseases. 75:6-8
Autor:
Stiina Aarum, Franz Koenig, Hanna Hedman, Matthias P. Hofer, Thorsten Vetter, Spiros Vamvakas, Martin Posch, Maria Mavris, Jan Regnstrom
Publikováno v:
Drug Discovery Today. 23:424-433
An analysis was performed on a data set of 157 orphan designated medicines with an outcome for marketing authorisation application (MAA) between 2000 and 2013. The intention was to understand the factors associated with marketing authorisation succes
Publikováno v:
Clinical Pharmacology & Therapeutics. 105:819-821