Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Thorsten, Bischler"'
Autor:
Amy-Jayne Hutchings, Bita Hambrecht, Alexander Veh, Neha Jadhav Giridhar, Abdolhossein Zare, Christina Angerer, Thorben Ohnesorge, Maren Schenke, Bhuvaneish T. Selvaraj, Siddharthan Chandran, Jared Sterneckert, Susanne Petri, Bettina Seeger, Michael Briese, Christian Stigloher, Thorsten Bischler, Andreas Hermann, Markus Damme, Michael Sendtner, Patrick Lüningschrör
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Increasing evidence suggests an essential function for autophagy in unconventional protein secretion (UPS). However, despite its relevance for the secretion of aggregate-prone proteins, the mechanisms of secretory autophagy in neurons have r
Externí odkaz:
https://doaj.org/article/eccb9961a162424bb27e46729a5df531
Autor:
Larissa Haertle, Umair Munawar, Hipólito N. C. Hernández, Andres Arroyo‐Barea, Tobias Heckel, Isabel Cuenca, Lucia Martin, Carlotta Höschle, Nicole Müller, Cornelia Vogt, Thorsten Bischler, Paula L. delCampo, Seungbin Han, Natalia Buenache, Xiang Zhou, Florian Bassermann, Johannes Waldschmidt, Torsten Steinbrunn, Leo Rasche, Thorsten Stühmer, Joaquin Martinez‐Lopez, K. Martin Kortüm, Santiago Barrio
Publikováno v:
HemaSphere, Vol 8, Iss 7, Pp n/a-n/a (2024)
Abstract Multiple myeloma (MM) is a genetically heterogeneous disease and the management of relapses is one of the biggest clinical challenges. TP53 alterations are established high‐risk markers and are included in the current disease staging crite
Externí odkaz:
https://doaj.org/article/315cbd46c5644a63a5886179cfc26c50
Autor:
Daniela Simone Maichl, Julius Arthur Kirner, Susanne Beck, Wen-Hui Cheng, Melanie Krug, Martin Kuric, Carsten Patrick Ade, Thorsten Bischler, Franz Jakob, Dirk Hose, Anja Seckinger, Regina Ebert, Franziska Jundt
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-6 (2023)
Externí odkaz:
https://doaj.org/article/b10e5b16bfdf4eef8d27ba0e27713f4c
Autor:
Kristof Brenzinger, Fabienne Maihoff, Marcell K. Peters, Leonie Schimmer, Thorsten Bischler, Alice Classen
Publikováno v:
iScience, Vol 25, Iss 10, Pp 105175- (2022)
Summary: Climate and land-use changes cause increasing stress to pollinators but the molecular pathways underlying stress responses are poorly understood. Here, we analyzed the transcriptomic response of Bombus lucorum workers to temperature and live
Externí odkaz:
https://doaj.org/article/aabd1721006b409897a8e7b4f69deb71
Autor:
Saskia Bauriedl, Milan Gerovac, Nadja Heidrich, Thorsten Bischler, Lars Barquist, Jörg Vogel, Christoph Schoen
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
FinO-domain proteins are bacterial RNA-binding proteins with a wide range of target specificities. Here, the authors employ UV CLIP-seq and show that minimal ProQ protein of Neisseria meningitidis binds to various small non-coding RNAs and mRNAs invo
Externí odkaz:
https://doaj.org/article/655596a4764d4f3a9233202e0aa98712
Autor:
Kotaro Chihara, Thorsten Bischler, Lars Barquist, Vivian A. Monzon, Naohiro Noda, Jörg Vogel, Satoshi Tsuneda
Publikováno v:
mSystems, Vol 4, Iss 6 (2019)
ABSTRACT Bacterial small noncoding RNAs (sRNAs) play posttranscriptional regulatory roles in cellular responses to changing environmental cues and in adaptation to harsh conditions. Generally, the RNA-binding protein Hfq helps sRNAs associate with ta
Externí odkaz:
https://doaj.org/article/7efc7b82d77d4339bcf87aafc32951ca
Autor:
Akua A. Karikari, Rhonda L. McFleder, Eliana Ribechini, Robert Blum, Valentin Bruttel, Susanne Knorr, Mona Gehmeyr, Jens Volkmann, Jonathan M. Brotchie, Fadhil Ahsan, Beatrice Haack, Camelia-Maria Monoranu, Ursula Keber, Rima Yeghiazaryan, Axel Pagenstecher, Tobias Heckel, Thorsten Bischler, Jörg Wischhusen, James B. Koprich, Manfred B. Lutz, Chi Wang Ip
Publikováno v:
Brain, Behavior, and Immunity. 101:194-210
Background Antigen-specific neuroinflammation and neurodegeneration are characteristic for neuroimmunological diseases. In Parkinson’s disease (PD) pathogenesis, α-synuclein is a known culprit. Evidence for α-synuclein-specific T cell responses w
Autor:
Gaurav Dugar, Sarah L. Svensson, Thorsten Bischler, Sina Wäldchen, Richard Reinhardt, Markus Sauer, Cynthia M. Sharma
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-18 (2016)
The CsrA protein binds to and represses translation of certain bacterial mRNAs. Here, Dugar et al. show for the human pathogen Campylobacter jejunithat the major flagellin mRNA acts as both a target and a regulatory 'sponge' for CsrA, and is localize
Externí odkaz:
https://doaj.org/article/3be9406422e4440bb0325020fd9d1cf9
Dual or Multi RNA-seq simultaneously analyze the transcriptomes of two or more interacting species to gain insights about their interplay. The RNA of the interacting species is collected and sequenced together and only separated in silico by mapping
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b36a64cd2056ac6e682e21d36aa30f8e
https://doi.org/10.1101/2022.09.30.510338
https://doi.org/10.1101/2022.09.30.510338
Autor:
Hannah G. Hampton, Peter C. Fineran, Thorsten Bischler, Aroa Rey Campa, Simon A. Jackson, Cynthia M. Sharma, Leah M Smith, Sahil Sharma
Publikováno v:
Nucleic Acids Research
CRISPR–Cas systems provide bacteria with adaptive immunity against phages and plasmids; however, pathways regulating their activity are not well defined. We recently developed a high-throughput genome-wide method (SorTn-seq) and used this to uncove