Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Thoresen GH"'
Publikováno v:
Toxicological Sciences. 61:83-91
Exposure to fluorides can induce inflammatory reactions, cell cycle arrest, and apoptosis in different experimental systems. Fluorides are known G-protein activators, but less is known about fluoride effects downstream of G-protein activation. The ai
Autor:
B. Lindeman, Lene Wierød, Henrik S. Huitfeldt, Ellen Skarpen, Thoralf Christoffersen, Thoresen Gh, Inger Helene Madshus
Publikováno v:
Molecular Carcinogenesis. 24:36-46
2-Acetylaminofluorene (AAF) is a potent tumor promoter in rat liver carcinogenesis models. In the resistant hepatocyte model, AAF is combined with a growth stimulus for efficient promotion of preneoplastic lesions. The promoting property of AAF in th
Publikováno v:
Journal of Cellular Physiology. 159:35-40
Previous data obtained in vivo and in vitro suggest that both prostaglandins (PGs) and catecholamines may have a role in promoting hepatocyte proliferation, and PGE2 and PGF2 alpha have also been implicated as mediators of the mitogenic actions of ep
Publikováno v:
Journal of Cellular Physiology. 151:164-171
Previous studies suggest that catecholamines may be involved in the regulation of liver growth. Considerable evidence implicates alpha 1-adrenergic mechanisms in the initiation of hepatocyte proliferation, while the role of beta-adrenoceptors is less
Autor:
Henrik S. Huitfeldt, Thoresen Gh, Ellen Skarpen, Kjetil Taskén, Per E. Schwarze, Jan Tore Samuelsen, Tore Jahnsen
Publikováno v:
Histochemistry and cell biology. 109(3)
Cyclic AMP (cAMP) is an important regulator of liver growth and differentiation. The main intracellular cAMP receptor, cAMP-dependent protein kinase (PKA), consists of two regulatory (R) and two catalytic (C) subunits. There are two classes, RI and R
Autor:
B. Lindeman, Ellen Skarpen, Marit Låg, Thoresen Gh, Henrik S. Huitfeldt, Thoralf Christoffersen
Publikováno v:
Histochemistry and cell biology. 104(4)
To elucidate cell differentiation in liver carcinogenesis, we have studied the CCAAT/enhancer-binding protein (C/EBP). C/EBP is a positive-acting transcription factor important for the maintenance of liverspecific functions. It is associated with dif
Autor:
Thoresen Gh, Thoralf Christoffersen
Publikováno v:
Cell biology international. 18(3)
Transforming growth factor beta 1 (TGF beta 1) elevated the phosphoenolpyruvate carboxykinase (PEPCK) mRNA abundance in primary cultures of rat hepatocytes. Although this increase was not as large as the rise in PEPCK gene expression induced by the c
Publikováno v:
Digestive diseases and sciences. 37(1)
Data presented indicate that in hepatocytes insulin and glucagon promote growth by acting in a relatively early part of the prereplicative period (G0 or early G1) whereas cells (if pretreated with insulin) become more sensitive to EGF at the later st
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Akademický článek
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