Výsledky vyhledávání - "Thorbjörn Lundh"

New Conceptual Toxicokinetic Model to Assess Synergistic Mixture Effects between the Aromatic Hydrocarbon β-Naphthoflavone and the Azole Nocodazole on the CYP1A Biomarker in a Fish Cell Line

Autor: Håvard G. Frøysa, Marie Mlnaříková, Charlotte Alvord, Shirin Fallahi, Guttorm Alendal, Malin Celander, Thorbjörn Lundh

Publikováno v: Environmental Science and Technology
13748-13758
Environmental Science & Technology

Toxicokinetic interactions with catabolic cytochrome P450 (CYP) enzymes can inhibit chemical elimination pathways and cause synergistic mixture effects. We have created a mathematical bottom-up model for a synergistic mixture effect where we fit a mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a033f532acf5c8d02fd2b17ec06c63
https://doi.org/10.1021/acs.est.0c04839

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