Výsledky vyhledávání - "Thoraval, Didier"

Doxorubicin Inhibits Phosphatidylserine Decarboxylase and Modifies Mitochondrial Membrane Composition in HeLa Cells

Autor: Bellance, Nadège, Furt, Fabienne, Melser, Su, Lalou, Claude, Thoraval, Didier, Maneta-Peyret, Lilly, Lacombe, Didier, Moreau, Patrick, Rossignol, Rodrigue

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1317 (2020)
International Journal of Molecular Sciences
International Journal of Molecular Sciences, MDPI, 2020, 21 (4), pp.1317. ⟨10.3390/ijms21041317⟩
Volume 21
Issue 4

Doxorubicin (DXR) is a drug widely used in chemotherapy. Its mode of action is based on its intercalation properties, involving the inhibition of topoisomerase II. However, few studies have reported the mitochondrial effects of DXR while investigatin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::669d6597cb597d9acdf8664e9e01ab3c
https://www.mdpi.com/1422-0067/21/4/1317

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Akademický článek

Autor: Amati-Bonneau Patrizia, Thoraval Didier, Murail Pascal, Chevrollier Arnaud, Rocher Christophe, Ferré Marc, Pierron Denis, Reynier Pascal, Letellier Thierry

Publikováno v: BMC Medical Genetics, Vol 10, Iss 1, p 70 (2009)

Abstract Background Leber's hereditary optic neuropathy (LHON) and autosomal dominant optic atrophy (ADOA) are the most frequent forms of hereditary optic neuropathies. LHON is associated with mitochondrial DNA (mtDNA) mutations whereas ADOA is mainl

Externí odkaz: https://doaj.org/article/d57cb598c154427899524b9d0304ca4c

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Akademický článek

New evidence of a mitochondrial genetic background paradox: Impact of the J haplogroup on the A3243G mutation

Autor: Pennarun Erwann, Arveiler Benoit, Bellanne-Chantelot Christine, Feldmann Delphine, Rotig Agnes, Godinot Catherine, de Camaret Benedicte, Batandier Cécile, Allouche Stéphane, Martin-Négrier Marie-Laure, Reynier Pascal, Amati-Bonneau Patricia, Rocher Christophe, Pierron Denis, Rossignol Rodrigue, Crouzet Marc, Murail Pascal, Thoraval Didier, Letellier Thierry

Publikováno v: BMC Medical Genetics, Vol 9, Iss 1, p 41 (2008)

Abstract Background The A3243G mutation in the tRNALeu gene (UUR), is one of the most common pathogenic mitochondrial DNA (mtDNA) mutations in France, and is associated with highly variable and heterogeneous disease phenotypes. To define the relation

Externí odkaz: https://doaj.org/article/1e0a95568fbf407c97d688a3914f0b5f

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Qualitative and quantitative study of the highly specialized lipid tissues of cetaceans using HR-MAS NMR and classical GC

Autor: Jung, Jean-Luc, Simon, Gaelle, Alfonsi, Eric, Thoraval, Didier, Kervarec, Nelly, Ben Salem, Douraied, Hassani, Sami, Domergue, Frédéric

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0180597 (2017)
PLoS ONE
PLoS ONE, Public Library of Science, 2017, 12 (7), pp.e0180597. ⟨10.1371/journal.pone.0180597⟩

International audience; Cetacean adipose tissues contain an extremely very wide variety of acyl-chains present in triacylglycerols and / or wax esters. In addition, changes in the lipid composition across organs suggest fine stratification. It theref

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::58fea4d037acb86902f3dd31ae214740
http://europepmc.org/articles/PMC5498043?pdf=render

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