Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications

Autor: Ebbesen, Morten Frendø, Kaspersen, Liselotte, Hansen, Irene M, Thomsen, Troels Kragsig, Bienk, Konrad, Cai, Yunpeng, Malle, Birgitte Mølholm, Howard, Kenneth Alan

Publikováno v: Ebbesen, M F, Ebbesen, M F, Kaspersen, L, Hansen, I M, Thomsen, T K, Bienk, K, Cai, Y, Malle, B M & Howard, K A 2017, ' Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications. ', Molecular Pharmaceutics, vol. 14, no. 7, pp. 2359-2367 . https://doi.org/10.1021/acs.molpharmaceut.7b00236
Hansen, I, Ebbesen, M F, Kaspersen, L, Thomsen, T B, Bienk, K, Cai, Y, Malle, B M & Howard, K 2017, ' Hyaluronic Acid Molecular Weight-Dependent Modulation of Mucin Nanostructure for Potential Mucosal Therapeutic Applications ', Molecular Pharmaceutics, vol. 14, no. 7, pp. 2359–2367 . https://doi.org/10.1021/acs.molpharmaceut.7b00236

This study investigates the effects of different molecular weight hyaluronic acids (HAs) on the mucosal nanostructure using a pig stomach mucin hydrogel as a mucosal barrier model. Microparticles (1.0 μm) and nanoparticles (200 nm) were used as prob

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331021d356aa2be8cd9a3637ee9555bd
https://doi.org/10.1021/acs.molpharmaceut.7b00236