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pro vyhledávání: '"Thoms JAI"'
© 2019 Wiley Periodicals, Inc. Acute myeloid leukemia (AML) is a complex disease characterized by a diverse range of recurrent molecular aberrations that occur in many different combinations. Components of transcriptional networks are a common targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::720bee0ea1ea2daacee3d3d36bf9e3e0
https://hdl.handle.net/10453/139385
https://hdl.handle.net/10453/139385
Autor:
Liu, Q, Thoms, JAI, Nunez, AC, Huang, Y, Knezevic, K, Packham, D, Poulos, RC, Williams, R, Beck, D, Hawkins, NJ, Ward, RL, Wong, JWH, Hesson, LB, Sloane, MA, Pimanda, JE
© 2018 American Association for Cancer Research. Purpose: MLH1 is a major tumor suppressor gene involved in the pathogenesis of Lynch syndrome and various sporadic cancers. Despite their potential pathogenic importance, genomic regions capable of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::7b2c35a822a91dcd3db42a49203877aa
https://hdl.handle.net/10453/131406
https://hdl.handle.net/10453/131406
Autor:
Huang, Y, Thoms, JAI, Tursky, ML, Knezevic, K, Beck, D, Chandrakanthan, V, Suryani, S, Olivier, J, Boulton, A, Glaros, EN, Thomas, SR, Lock, RB, MacKenzie, KL, Bushweller, JH, Wong, JWH, Pimanda, JE
© 2016 Macmillan Publishers Limited. Aberrant ERG (v-ets avian erythroblastosis virus E26 oncogene homolog) expression drives leukemic transformation in mice and high expression is associated with poor patient outcomes in acute myeloid leukemia (AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e0e3e659eefb9c256627029c2d4c2e94
https://hdl.handle.net/10453/98275
https://hdl.handle.net/10453/98275
Autor:
Tursky, ML, Beck, D, Thoms, JAI, Huang, Y, Kumari, A, Unnikrishnan, A, Knezevic, K, Evans, K, Richards, LA, Lee, E, Morris, J, Goldberg, L, Izraeli, S, Wong, JWH, Olivier, J, Lock, RB, MacKenzie, KL, Pimanda, JE
© 2015 Macmillan Publishers Limited. High expression of the ETS family transcription factor ERG is associated with poor clinical outcome in acute myeloid leukemia (AML) and acute T-cell lymphoblastic leukemia (T-ALL). In murine models, high ERG expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::c0bf480893f03e06ad732bd61472b0a3
https://hdl.handle.net/10453/132444
https://hdl.handle.net/10453/132444
Autor:
Beck, D, Thoms, JAI, Perera, D, Schütte, J, Unnikrishnan, A, Knezevic, K, Kinston, SJ, Wilson, NK, O'Brien, TA, Göttgens, B, Wong, JWH, Pimanda, JE
© 2013 by The American Society of Hematology. Genome-wide combinatorial binding patterns for key transcription factors (TFs) have not been reported for primary human hematopoietic stem and progenitor cells (HSPCs), and have constrained analysis of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::000f9ad0162498e14715e980dadbcd54
https://hdl.handle.net/10453/116740
https://hdl.handle.net/10453/116740
Autor:
Beck, D, Thoms, JAI, Palu, C, Herold, T, Shah, A, Olivier, J, Boelen, L, Huang, Y, Chacon, D, Brown, A, Babic, M, Hahn, C, Perugini, M, Zhou, X, Huntly, BJ, Schwarzer, A, Klusmann, J-H, Berdel, WE, Wörmann, B, Büchner, T, Hiddemann, W, Bohlander, SK, To, LB, Scott, HS, Lewis, ID, D'Andrea, RJ, Wong, JWH, Pimanda, JE
Prognostic gene expression signatures have been proposed as clinical tools to clarify therapeutic options in acute myeloid leukemia (AML). However, these signatures rely on measuring large numbers of genes and often perform poorly when applied to ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28add5bb5c7dd22f1b496bf82779864d
Autor:
Thoms JAI; School of Biomedical Sciences, University of New South Wales, Sydney, Australia., Koch FC; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia., Raei A; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia., Subramanian S; School of Clinical Medicine, University of New South Wales, Sydney, Australia., Wong JWH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Vafaee F; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.; UNSW Data Science Hub, University of New South Wales, Sydney, Australia., Pimanda JE; School of Biomedical Sciences, University of New South Wales, Sydney, Australia.; School of Clinical Medicine, University of New South Wales, Sydney, Australia.; Haematology Department, Prince of Wales Hospital, Sydney, Australia.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2024 Jan 05; Vol. 52 (D1), pp. D1131-D1137.
Autor:
Subramanian S; School of Clinical Medicine, University of New South Wales, Sydney, Australia., Thoms JAI; School of Biomedical Sciences, University of New South Wales, Sydney, Australia., Huang Y; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology Sydney, Sydney, Australia., Cornejo-Páramo P; Victor Chang Cardiac Research Institute, Sydney, Australia., Koch FC; School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, Australia., Jacquelin S; Macrophage Biology Laboratory, Mater Research, Brisbane, Australia., Shen S; Bone Marrow Transplant Laboratory, NSW Health Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Song E; Bone Marrow Transplant Laboratory, NSW Health Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Joshi S; School of Clinical Medicine, University of New South Wales, Sydney, Australia., Brownlee C; Mark Wainwright Analytical Centre, University of New South Wales, Sydney, Australia., Woll PS; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Huddinge, Sweden., Chacon-Fajardo D; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology Sydney, Sydney, Australia., Beck D; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology Sydney, Sydney, Australia., Curtis DJ; Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia., Yehson K; Blood Transplant and Cell Therapies Laboratory, NSW Health Pathology, Westmead, NSW, Australia., Antonenas V; Blood Transplant and Cell Therapies Laboratory, NSW Health Pathology, Westmead, NSW, Australia., O'Brien T; Sydney Children's Hospital, Sydney, Australia., Trickett A; Bone Marrow Transplant Laboratory, NSW Health Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Powell JA; Centre for Cancer Biology, SA Pathology, University of South Australia, Adelaide, Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, Australia., Lewis ID; Centre for Cancer Biology, SA Pathology, University of South Australia, Adelaide, Australia., Pitson SM; Centre for Cancer Biology, SA Pathology, University of South Australia, Adelaide, Australia., Gandhi MK; Blood Cancer Research Group, Mater Research, The University of Queensland, Brisbane, QLD, Australia., Lane SW; Cancer Program, QIMR Berghofer Medical Research, Brisbane, Australia., Vafaee F; School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, Australia.; UNSW Data Science Hub, University of New South Wales, Sydney, Australia., Wong ES; Victor Chang Cardiac Research Institute, Sydney, Australia.; School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, Australia., Göttgens B; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom., Alinejad-Rokny H; BioMedical Machine Learning Lab, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia., Wong JWH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Pimanda JE; School of Clinical Medicine, University of New South Wales, Sydney, Australia.; School of Biomedical Sciences, University of New South Wales, Sydney, Australia.; Haematology Department, Prince of Wales Hospital, Sydney, Australia.
Publikováno v:
Blood [Blood] 2023 Oct 26; Vol. 142 (17), pp. 1448-1462.
Autor:
Kugler E; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel., Madiwale S; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Yong D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Thoms JAI; Adult Cancer Program, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia., Birger Y; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Sykes DB; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA & Harvard Stem Cell Institute, Cambridge, MA, USA., Schmoellerl J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Drakul A; Division of Pediatric Oncology, and Children Research Center, University Children's Hospital, Zurich, Switzerland., Priebe V; Division of Pediatric Oncology, and Children Research Center, University Children's Hospital, Zurich, Switzerland., Yassin M; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Aqaqe N; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Rein A; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Fishman H; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Geron I; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Chen CW; Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte, CA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Raught B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Liu Q; Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte, CA, USA., Ogana H; Department of Pediatrics, Division of Hematology and Oncology, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA., Liedke E; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Bourquin JP; Division of Pediatric Oncology, and Children Research Center, University Children's Hospital, Zurich, Switzerland., Zuber J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Medical University of Vienna, Vienna, Austria., Milyavsky M; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Pimanda J; Adult Cancer Program, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia., Privé GG; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. Gil.Prive@uhnresearch.ca.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada. Gil.Prive@uhnresearch.ca., Izraeli S; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. sizraeli@gmail.com.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel. sizraeli@gmail.com.
Publikováno v:
Nature communications [Nat Commun] 2023 Sep 21; Vol. 14 (1), pp. 5871. Date of Electronic Publication: 2023 Sep 21.
Autor:
Schnegg-Kaufmann AS; School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Department of Hematology and Central Hematology Laboratory, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department for Biomedical Research, University of Bern, Bern, Switzerland., Thoms JAI; School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Bhuyan GS; School of Clinical Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Hampton HR; School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Vaughan L; School of Clinical Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Institute of Clinical Pathology and Medical Research, Westmead Hospital, Sydney, NSW, Australia.; Haematology Department, Westmead Hospital, Sydney, NSW, Australia., Rutherford K; Department of Epidemiology and Biostatistics, Computational Oncology Service, Center for Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Kakadia PM; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, The University of Auckland, Auckland, New Zealand., Lee HM; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, The University of Auckland, Auckland, New Zealand., Johansson EMV; Flow Cytometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Failes TW; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Australian Cancer Research Foundation (ACRF) Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Arndt GM; School of Clinical Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Australian Cancer Research Foundation (ACRF) Drug Discovery Centre for Childhood Cancer, Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Koval J; Ramaciotti Centre for Genomics, UNSW Sydney, Sydney, NSW, Australia., Lindeman R; Department of Clinical Haematology, Prince of Wales Hospital, Sydney, NSW, Australia., Warburton P; Department of Haematology, Wollongong Hospital, Wollongong, NSW, Australia., Rodriguez-Meira A; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Mead AJ; Haematopoietic Stem Cell Biology Laboratory, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom., Unnikrishnan A; School of Clinical Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Davidson S; ANU Clinical Hub for Interventional Research (CHOIR), John Curtin School of Medical Research, Canberra, Australia., Polizzotto MN; ANU Clinical Hub for Interventional Research (CHOIR), John Curtin School of Medical Research, Canberra, Australia., Hertzberg M; Department of Clinical Haematology, Prince of Wales Hospital, Sydney, NSW, Australia., Papaemmanuil E; Department of Epidemiology and Biostatistics, Computational Oncology Service, Center for Computational Oncology, Memorial Sloan Kettering Cancer Center, New York, NY., Bohlander SK; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, The University of Auckland, Auckland, New Zealand., Faridani OR; School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Garvan-Weizmann Centre for Cellular Genomics, Sydney, NSW, Australia.; Cellular Genomics Futures Institute, UNSW Sydney, Sydney, NSW, Australia., Jolly CJ; School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia., Zanini F; School of Clinical Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Garvan-Weizmann Centre for Cellular Genomics, Sydney, NSW, Australia.; Cellular Genomics Futures Institute, UNSW Sydney, Sydney, NSW, Australia., Pimanda JE; School of Biomedical Sciences, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Clinical Medicine, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; Department of Clinical Haematology, Prince of Wales Hospital, Sydney, NSW, Australia.
Publikováno v:
Blood [Blood] 2023 Mar 16; Vol. 141 (11), pp. 1316-1321.