Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Thoms JAI"'
© 2019 Wiley Periodicals, Inc. Acute myeloid leukemia (AML) is a complex disease characterized by a diverse range of recurrent molecular aberrations that occur in many different combinations. Components of transcriptional networks are a common targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::720bee0ea1ea2daacee3d3d36bf9e3e0
https://hdl.handle.net/10453/139385
https://hdl.handle.net/10453/139385
Autor:
Liu, Q, Thoms, JAI, Nunez, AC, Huang, Y, Knezevic, K, Packham, D, Poulos, RC, Williams, R, Beck, D, Hawkins, NJ, Ward, RL, Wong, JWH, Hesson, LB, Sloane, MA, Pimanda, JE
© 2018 American Association for Cancer Research. Purpose: MLH1 is a major tumor suppressor gene involved in the pathogenesis of Lynch syndrome and various sporadic cancers. Despite their potential pathogenic importance, genomic regions capable of re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::7b2c35a822a91dcd3db42a49203877aa
https://hdl.handle.net/10453/131406
https://hdl.handle.net/10453/131406
Autor:
Huang, Y, Thoms, JAI, Tursky, ML, Knezevic, K, Beck, D, Chandrakanthan, V, Suryani, S, Olivier, J, Boulton, A, Glaros, EN, Thomas, SR, Lock, RB, MacKenzie, KL, Bushweller, JH, Wong, JWH, Pimanda, JE
© 2016 Macmillan Publishers Limited. Aberrant ERG (v-ets avian erythroblastosis virus E26 oncogene homolog) expression drives leukemic transformation in mice and high expression is associated with poor patient outcomes in acute myeloid leukemia (AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::e0e3e659eefb9c256627029c2d4c2e94
https://hdl.handle.net/10453/98275
https://hdl.handle.net/10453/98275
Autor:
Tursky, ML, Beck, D, Thoms, JAI, Huang, Y, Kumari, A, Unnikrishnan, A, Knezevic, K, Evans, K, Richards, LA, Lee, E, Morris, J, Goldberg, L, Izraeli, S, Wong, JWH, Olivier, J, Lock, RB, MacKenzie, KL, Pimanda, JE
© 2015 Macmillan Publishers Limited. High expression of the ETS family transcription factor ERG is associated with poor clinical outcome in acute myeloid leukemia (AML) and acute T-cell lymphoblastic leukemia (T-ALL). In murine models, high ERG expr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::c0bf480893f03e06ad732bd61472b0a3
https://hdl.handle.net/10453/132444
https://hdl.handle.net/10453/132444
Autor:
Beck, D, Thoms, JAI, Perera, D, Schütte, J, Unnikrishnan, A, Knezevic, K, Kinston, SJ, Wilson, NK, O'Brien, TA, Göttgens, B, Wong, JWH, Pimanda, JE
© 2013 by The American Society of Hematology. Genome-wide combinatorial binding patterns for key transcription factors (TFs) have not been reported for primary human hematopoietic stem and progenitor cells (HSPCs), and have constrained analysis of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______363::000f9ad0162498e14715e980dadbcd54
https://hdl.handle.net/10453/116740
https://hdl.handle.net/10453/116740
Autor:
Beck, D, Thoms, JAI, Palu, C, Herold, T, Shah, A, Olivier, J, Boelen, L, Huang, Y, Chacon, D, Brown, A, Babic, M, Hahn, C, Perugini, M, Zhou, X, Huntly, BJ, Schwarzer, A, Klusmann, J-H, Berdel, WE, Wörmann, B, Büchner, T, Hiddemann, W, Bohlander, SK, To, LB, Scott, HS, Lewis, ID, D'Andrea, RJ, Wong, JWH, Pimanda, JE
Prognostic gene expression signatures have been proposed as clinical tools to clarify therapeutic options in acute myeloid leukemia (AML). However, these signatures rely on measuring large numbers of genes and often perform poorly when applied to ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28add5bb5c7dd22f1b496bf82779864d
Autor:
Truong P; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Shen S; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Joshi S; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Islam MI; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Zhong L; Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Raftery MJ; Bioanalytical Mass Spectrometry Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Afrasiabi A; UNSW BioMedical Machine Learning Lab (BML), The Graduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia., Alinejad-Rokny H; UNSW BioMedical Machine Learning Lab (BML), The Graduate School of Biomedical Engineering, UNSW Sydney, Sydney, NSW, Australia.; Tyree Institute of Health Engineering (IHealthE), UNSW Sydney, Sydney, NSW, Australia., Nguyen M; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Zou X; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Bhuyan GS; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Sarowar CH; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Ghodousi ES; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia., Stonehouse O; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Mohamed S; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Toscan CE; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Connerty P; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Kakadia PM; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Bohlander SK; Leukaemia and Blood Cancer Research Unit, Department of Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand., Michie KA; Structural Biology Facility, Mark Wainwright Analytical Centre, UNSW Sydney, Sydney, NSW, Australia., Larsson J; Division of Molecular Medicine and Gene Therapy, Lund Stem Cell Centre, Lund University, Lund, Sweden., Lock RB; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia.; Children's Cancer Institute, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; UNSW Centre for Childhood Cancer Research, UNSW Sydney, Sydney, NSW, Australia., Walkley CR; St Vincent's Institute of Medical Research, University of Melbourne, Melbourne, VIC, Australia.; Department of Medicine, University of Melbourne, Melbourne, VIC, Australia., Thoms JAI; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia., Jolly CJ; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia. c.jolly@unsw.edu.au., Pimanda JE; School of Clinical Medicine, UNSW Medicine & Health, UNSW Sydney, Sydney, NSW, Australia. jpimanda@unsw.edu.au.; School of Biomedical Sciences, UNSW Sydney, Sydney, NSW, Australia. jpimanda@unsw.edu.au.; Haematology Department, Prince of Wales Hospital, Sydney, NSW, Australia. jpimanda@unsw.edu.au.
Publikováno v:
Nature communications [Nat Commun] 2024 Aug 28; Vol. 15 (1), pp. 7360. Date of Electronic Publication: 2024 Aug 28.
Autor:
Thoms JAI; School of Biomedical Sciences, University of New South Wales, Sydney, Australia., Koch FC; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia., Raei A; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia., Subramanian S; School of Clinical Medicine, University of New South Wales, Sydney, Australia., Wong JWH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Vafaee F; School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, Australia.; UNSW Data Science Hub, University of New South Wales, Sydney, Australia., Pimanda JE; School of Biomedical Sciences, University of New South Wales, Sydney, Australia.; School of Clinical Medicine, University of New South Wales, Sydney, Australia.; Haematology Department, Prince of Wales Hospital, Sydney, Australia.
Publikováno v:
Nucleic acids research [Nucleic Acids Res] 2024 Jan 05; Vol. 52 (D1), pp. D1131-D1137.
Autor:
Subramanian S; School of Clinical Medicine, University of New South Wales, Sydney, Australia., Thoms JAI; School of Biomedical Sciences, University of New South Wales, Sydney, Australia., Huang Y; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology Sydney, Sydney, Australia., Cornejo-Páramo P; Victor Chang Cardiac Research Institute, Sydney, Australia., Koch FC; School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, Australia., Jacquelin S; Macrophage Biology Laboratory, Mater Research, Brisbane, Australia., Shen S; Bone Marrow Transplant Laboratory, NSW Health Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Song E; Bone Marrow Transplant Laboratory, NSW Health Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Joshi S; School of Clinical Medicine, University of New South Wales, Sydney, Australia., Brownlee C; Mark Wainwright Analytical Centre, University of New South Wales, Sydney, Australia., Woll PS; Department of Medicine, Center for Hematology and Regenerative Medicine, Karolinska Institutet, Huddinge, Sweden., Chacon-Fajardo D; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology Sydney, Sydney, Australia., Beck D; Centre for Health Technologies and the School of Biomedical Engineering, University of Technology Sydney, Sydney, Australia., Curtis DJ; Australian Centre for Blood Diseases, Monash University, Melbourne, VIC, Australia., Yehson K; Blood Transplant and Cell Therapies Laboratory, NSW Health Pathology, Westmead, NSW, Australia., Antonenas V; Blood Transplant and Cell Therapies Laboratory, NSW Health Pathology, Westmead, NSW, Australia., O'Brien T; Sydney Children's Hospital, Sydney, Australia., Trickett A; Bone Marrow Transplant Laboratory, NSW Health Pathology, Prince of Wales Hospital, Randwick, NSW, Australia., Powell JA; Centre for Cancer Biology, SA Pathology, University of South Australia, Adelaide, Australia.; Adelaide Medical School, The University of Adelaide, Adelaide, Australia., Lewis ID; Centre for Cancer Biology, SA Pathology, University of South Australia, Adelaide, Australia., Pitson SM; Centre for Cancer Biology, SA Pathology, University of South Australia, Adelaide, Australia., Gandhi MK; Blood Cancer Research Group, Mater Research, The University of Queensland, Brisbane, QLD, Australia., Lane SW; Cancer Program, QIMR Berghofer Medical Research, Brisbane, Australia., Vafaee F; School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, Australia.; UNSW Data Science Hub, University of New South Wales, Sydney, Australia., Wong ES; Victor Chang Cardiac Research Institute, Sydney, Australia.; School of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales, Sydney, Australia., Göttgens B; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, United Kingdom., Alinejad-Rokny H; BioMedical Machine Learning Lab, Graduate School of Biomedical Engineering, University of New South Wales, Sydney, Australia., Wong JWH; School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China., Pimanda JE; School of Clinical Medicine, University of New South Wales, Sydney, Australia.; School of Biomedical Sciences, University of New South Wales, Sydney, Australia.; Haematology Department, Prince of Wales Hospital, Sydney, Australia.
Publikováno v:
Blood [Blood] 2023 Oct 26; Vol. 142 (17), pp. 1448-1462.
Autor:
Kugler E; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; Institute of Hematology, Davidoff Cancer Center, Rabin Medical Center, Petah Tikva, Israel., Madiwale S; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Yong D; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Thoms JAI; Adult Cancer Program, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia., Birger Y; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Sykes DB; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, USA & Harvard Stem Cell Institute, Cambridge, MA, USA., Schmoellerl J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria., Drakul A; Division of Pediatric Oncology, and Children Research Center, University Children's Hospital, Zurich, Switzerland., Priebe V; Division of Pediatric Oncology, and Children Research Center, University Children's Hospital, Zurich, Switzerland., Yassin M; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Aqaqe N; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Rein A; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Fishman H; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Geron I; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel., Chen CW; Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte, CA, USA.; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.; City of Hope Comprehensive Cancer Center, Duarte, CA, USA., Raught B; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada., Liu Q; Department of Systems Biology, Beckman Research Institute, City of Hope, Duarte, CA, USA., Ogana H; Department of Pediatrics, Division of Hematology and Oncology, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA., Liedke E; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada., Bourquin JP; Division of Pediatric Oncology, and Children Research Center, University Children's Hospital, Zurich, Switzerland., Zuber J; Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), Vienna, Austria.; Medical University of Vienna, Vienna, Austria., Milyavsky M; Department of Pathology, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel., Pimanda J; Adult Cancer Program, Lowy Cancer Research Centre, UNSW Sydney, Sydney, NSW, Australia.; School of Biomedical Sciences, Faculty of Medicine, UNSW Sydney, Sydney, NSW, Australia., Privé GG; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada. Gil.Prive@uhnresearch.ca.; Department of Biochemistry, University of Toronto, Toronto, ON, Canada. Gil.Prive@uhnresearch.ca., Izraeli S; Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel. sizraeli@gmail.com.; The Rina Zaizov Pediatric Hematology and Oncology Division Schneider Children's Medical Center of Israel, Petach Tikva, Israel. sizraeli@gmail.com.
Publikováno v:
Nature communications [Nat Commun] 2023 Sep 21; Vol. 14 (1), pp. 5871. Date of Electronic Publication: 2023 Sep 21.