Výsledky vyhledávání - "Thompson Karol L"

Akademický článek

Improvement in the Reproducibility and Accuracy of DNA Microarray Quantification by Optimizing Hybridization Conditions

Autor: Han Tao, Melvin Cathy D, Shi Leming, Branham William S, Moland Carrie L, Pine P Scott, Thompson Karol L, Fuscoe James C

Publikováno v: BMC Bioinformatics, Vol 7, Iss Suppl 2, p S17 (2006)

Abstract Background DNA microarrays, which have been increasingly used to monitor mRNA transcripts at a global level, can provide detailed insight into cellular processes involved in response to drugs and toxins. This is leading to new understandings

Externí odkaz: https://doaj.org/article/c70ede8f74624adf872e67bdb565a037

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Akademický článek

An adaptable method using human mixed tissue ratiometric controls for benchmarking performance on gene expression microarrays in clinical laboratories

Autor: Rosenzweig Barry A, Pine P Scott, Thompson Karol L

Publikováno v: BMC Biotechnology, Vol 11, Iss 1, p 38 (2011)

Abstract Background Molecular biomarkers that are based on mRNA transcripts are being developed for the diagnosis and treatment of a number of diseases. DNA microarrays are one of the primary technologies being used to develop classifiers from gene e

Externí odkaz: https://doaj.org/article/d22089d7023342ecb6e6fae4d70dcfa5

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Akademický článek

Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories

Autor: Lee Janice S, Hester Susan, Fostel Jennifer, Corton J Christopher, Cooper Matthew, Chou Jeff W, Bushel Pierre R, Bass Michael B, Wolfinger Russell D, Boedigheimer Michael J, Liu Fenglong, Liu Jie, Qian Hui-Rong, Quackenbush John, Pettit Syril, Thompson Karol L

Publikováno v: BMC Genomics, Vol 9, Iss 1, p 285 (2008)

Abstract Background The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from

Externí odkaz: https://doaj.org/article/b64a8aed969c4e0dbc163da72cc750db

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Akademický článek

Characterization of the effect of sample quality on high density oligonucleotide microarray data using progressively degraded rat liver RNA

Autor: Rosenzweig Barry A, Pine P Scott, Thompson Karol L, Turpaz Yaron, Retief Jacques

Publikováno v: BMC Biotechnology, Vol 7, Iss 1, p 57 (2007)

Abstract Background The interpretability of microarray data can be affected by sample quality. To systematically explore how RNA quality affects microarray assay performance, a set of rat liver RNA samples with a progressive change in RNA integrity w

Externí odkaz: https://doaj.org/article/2acbbbe3e7c14cdeb088c66ce96de258

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