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NOTUM inhibition increases endocortical bone formation and bone strength.

Autor: Brommage R; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 3Present Address: Centre for Bone and Arthritis Research, University of Gothenburg, Gothenburg, Sweden., Liu J; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 4Present Address: Biogen, Cambridge, MA, USA., Vogel P; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 5Present Address: St. Jude Children's Research Hospital, Memphis, TN USA., Mseeh F; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 6Present Address: MD Anderson Cancer Center, Houston, TX USA., Thompson AY; 1Lexicon Pharmaceuticals, The Woodlands, TX USA., Potter DG; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; Present Address: Bethyl Laboratories, Montgomery, TX USA., Shadoan MK; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 8Present Address: Merck, Rahway, NJ USA., Hansen GM; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; Present Address: Nurix, San Francisco, CA USA., Jeter-Jones S; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 6Present Address: MD Anderson Cancer Center, Houston, TX USA., Cui J; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; Present Address: Wntrix, Houston, TX USA., Bright D; 1Lexicon Pharmaceuticals, The Woodlands, TX USA., Bardenhagen JP; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 6Present Address: MD Anderson Cancer Center, Houston, TX USA., Doree DD; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 11Present Address: PRA Health Sciences, Raleigh, NC USA., Movérare-Skrtic S; 2Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Nilsson KH; 2Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Henning P; 2Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Lerner UH; 2Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Ohlsson C; 2Centre for Bone and Arthritis Research, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden., Sands AT; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; Present Address: Nurix, San Francisco, CA USA., Tarver JE; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 12Present Address: University of Pennsylvania, Philadelphia, PA USA., Powell DR; 1Lexicon Pharmaceuticals, The Woodlands, TX USA., Zambrowicz B; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 13Present Address: Regeneron Pharmaceuticals, Tarrytown, NY USA., Liu Q; 1Lexicon Pharmaceuticals, The Woodlands, TX USA.; 14Present Address: University of Texas, Houston, TX USA.

Publikováno v: Bone research [Bone Res] 2019 Jan 08; Vol. 7, pp. 2. Date of Electronic Publication: 2019 Jan 08 (Print Publication: 2019).