A functional genomics pipeline to identify high-value asthma and allergy CpGs in the human methylome

Autor: Morin, Andréanne, Thompson, Emma E., Helling, Britney A., Shorey-Kendrick, Lyndsey E., Faber, Pieter, Gebretsadik, Tebeb, Bacharier, Leonard B., Kattan, Meyer, O’Connor, George T., Rivera-Spoljaric, Katherine, Wood, Robert A., Barnes, Kathleen C., Mathias, Rasika A., Altman, Matthew C., Hansen, Kasper, McEvoy, Cindy T., Spindel, Eliot R., Hartert, Tina, Jackson, Daniel J., Gern, James E., McKennan, Chris G., Ober, Carole

Publikováno v: In The Journal of Allergy and Clinical Immunology December 2022

Multi-omic association study identifies DNA methylation-mediated genotype and smoking exposure effects on lung function in children living in urban settings.

Autor: Dapas, Matthew¹ (AUTHOR) mdapas@uchicago.edu, Thompson, Emma E.¹ (AUTHOR), Wentworth-Sheilds, William¹ (AUTHOR), Clay, Selene¹ (AUTHOR), Visness, Cynthia M.² (AUTHOR), Calatroni, Agustin² (AUTHOR), Sordillo, Joanne E.³ (AUTHOR), Gold, Diane R.^4,5 (AUTHOR), Wood, Robert A.⁶ (AUTHOR), Makhija, Melanie⁷ (AUTHOR), Khurana Hershey, Gurjit K.^8,9 (AUTHOR), Sherenian, Michael G.^8,9 (AUTHOR), Gruchalla, Rebecca S.¹⁰ (AUTHOR), Gill, Michelle A.¹¹ (AUTHOR), Liu, Andrew H.¹² (AUTHOR), Kim, Haejin¹³ (AUTHOR), Kattan, Meyer¹⁴ (AUTHOR), Bacharier, Leonard B.¹⁵ (AUTHOR), Rastogi, Deepa¹⁶ (AUTHOR), Altman, Matthew C.¹⁷ (AUTHOR)

Publikováno v: PLoS Genetics. 1/13/2023, Vol. 18 Issue 1, p1-32. 32p.

Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants

Autor: van der Valk, Ralf J.P., Duijts, Liesbeth, Timpson, Nicolas J., Salam, Muhammad T., Standl, Marie, Curtin, John A., Genuneit, Jon, Kerhof, Marjan, Kreiner-Møller, Eskil, Cáceres, Alejandro, Gref, Anna, Liang, Liming L., Taal, H. Rob, Bouzigon, Emmanuelle, Demenais, Florence, Nadif, Rachel, Ober, Carole, Thompson, Emma E., Estrada, Karol, Hofman, Albert, Uitterlinden, André G., van Duijn, Cornélia, Rivadeneira, Fernando, Li, Xia, Eckel, Sandrah P., Berhane, Kiros, Gauderman, W. James, Granell, Raquel, Evans, David M., St Pourcain, Beate, McArdle, Wendy, Kemp, John P., Smith, George Davey, Tiesler, Carla M.T., Flexeder, Claudia, Simpson, Angela, Murray, Clare S., Fuchs, Oliver, Postma, Dirkje S., Bønnelykke, Klaus, Torrent, Maties, Andersson, Martin, Sleiman, Patrick, Hakonarson, Hakon, Cookson, William O., Moffatt, Miriam F., Paternoster, Lavinia, Melén, Erik, Sunyer, Jordi, Bisgaard, Hans, Koppelman, Gerard H., Ege, Markus, Custovic, Adnan, Heinrich, Joachim, Gilliland, Frank D., Henderson, Alexander J., Jaddoe, Vincent W.V., de Jongste, Johan C.

Publikováno v: In The Journal of Allergy and Clinical Immunology July 2014 134(1):46-55

Cytokine-induced molecular responses in airway smooth muscle cells inform genome-wide association studies of asthma.

Autor: Thompson, Emma E.¹ (AUTHOR) eethomps@uchicago.edu, Dang, Quynh² (AUTHOR), Mitchell-Handley, Blair¹ (AUTHOR), Rajendran, Kavitha² (AUTHOR), Ram-Mohan, Sumati² (AUTHOR), Solway, Julian³ (AUTHOR), Ober, Carole¹ (AUTHOR), Krishnan, Ramaswamy² (AUTHOR)

Publikováno v: Genome Medicine. 7/20/2020, Vol. 12 Issue 1, p1-14. 14p.

Functional constraints on the constitutive androstane receptor inferred from human sequence variation and cross-species comparisons

Autor: Thompson Emma E, Kuttab-Boulos Hala, Krasowski Matthew D, Di Rienzo Anna

Publikováno v: Human Genomics, Vol 2, Iss 3, Pp 168-178 (2005)

Abstract Members of the NR1I subfamily of nuclear receptors play a role in the transcriptional activation of genes involved in drug metabolism and transport. NR1I3, the constitutive androstane receptor (CAR), mediates the induction of several genes i

Externí odkaz: https://doaj.org/article/3d1bd4902fa5442da5f75f02f1b3e632