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pro vyhledávání: '"Thompson, Alexandra Inés"'
Autor:
Thompson, Alexandra Inés
Introduction: Hepatic stellate cells (HSC) and myofibroblasts may be relevant stromal drivers of human hepatocellular carcinoma (HCC). It was hypothesised that targeted inhibition of αv integrin-mediated TGF-β activation, by HSC or hepatocytes, may
Externí odkaz:
https://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.738879
Autor:
Gamal, Wesam, Treskes, Philipp, Samuel, Kay, Sullivan, Gareth J., Siller, Richard, Srsen, Vlastimil, Morgan, Katie, Bryans, Anna, Kozlowska, Ada, Koulovasilopoulos, Andreas, Underwood, Ian, Smith, Stewart, del-Pozo, Jorge, Moss, Sharon, Thompson, Alexandra Inés, Henderson, Neil C., Hayes, Peter C., Plevris, John N., Bagnaninchi, Pierre-Olivier, Nelson, Leonard J.
Publikováno v:
Gamal, W, Treskes, P, Samuel, K, Sullivan, G J, Siller, R, Srsen, V, Morgan, K, Bryans, A, Kozlowska, A, Koulovasilopoulos, A, Underwood, I, Smith, S, del-Pozo, J, Moss, S, Thompson, A I, Henderson, N C, Hayes, P C, Plevris, J N, Bagnaninchi, P-O & Nelson, L J 2017, ' Low-dose acetaminophen induces early disruption of cell-cell tight junctions in human hepatic cells and mouse liver ', Scientific Reports, vol. 7, 37541 . https://doi.org/10.1038/srep37541
Scientific Reports
Scientific Reports
Dysfunction of cell-cell tight junction (TJ) adhesions is a major feature in the pathogenesis of various diseases. Liver TJs preserve cellular polarity by delimiting functional bile-canalicular structures, forming the blood-biliary barrier. In acetam