CFT7455, a novel IKZF1/3 degrader, demonstrates potent activity in peripheral and CNS models of NHL as a single agent or in combination with clinically approved agents.

Autor: Thomenius, M. J., Perino, S., Kirby, J., Agafonov, R., Chaturvedi, P., Eron, S., Good, A., Hart, J. A., He, M., Phillips, A., Proia, D. A., Henderson, J. A., Nasveschuk, C., Fisher, S. L., Pollock, R. M.

Publikováno v: Hematological Oncology; Jun2023 Supplement S2, Vol. 41, p550-551, 2p

RTP801 mediates transneuronal toxicity in culture via extracellular vesicles.

Autor: Solana-Balaguer, Júlia^1,2,3 juliasolana@ub.edu, Martín-Flores, Núria^1,2 n.flores@ucl.ac.uk, Garcia-Segura, Pol^1,2,3, Campoy-Campos, Genís^1,2,3, Pérez-Sisqués, Leticia^1,2, Chicote-González, Almudena^1,2,3, Fernández-Irigoyen, Joaquín⁴, Santamaría, Enrique⁴, Pérez-Navarro, Esther^1,2,3,5, Alberch, Jordi^1,2,3,5, Malagelada, Cristina^1,2,3 cristina.malagelada@ub.edu

Publikováno v: Journal of Extracellular Vesicles. Nov2023, Vol. 12 Issue 11, p1-26. 26p.

Unmasking Protein Phosphatase 2A Regulatory Subunit B as a Crucial Factor in the Progression of Dilated Cardiomyopathy.

Autor: Lin, Fang, Liang, Xiaoting, Meng, Yilei, Zhu, Yuping, Li, Chenyu, Zhou, Xiaohui, Hu, Sangyu, Yi, Na, Lin, Qin, He, Siyu, Sun, Yizhuo, Sheng, Jie, Fan, Huimin, Li, Li, Peng, Luying

Publikováno v: Biomedicines; Aug2024, Vol. 12 Issue 8, p1887, 16p

Unveiling the Mechanism of Protective Effects of Tanshinone as a New Fighter Against Cardiovascular Diseases: A Systematic Review.

Autor: Dabbaghi MM; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Azadi Sq, Vakil Abad Highway, Mashhad, 9177948564, Iran., Soleimani Roudi H; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Azadi Sq, Vakil Abad Highway, Mashhad, 9177948564, Iran., Safaei R; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Azadi Sq, Vakil Abad Highway, Mashhad, 9177948564, Iran., Baradaran Rahimi V; Department of Cardiovascular Diseases, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran., Fadaei MR; Department of Pharmaceutics, School of Pharmacy, Mashhad University of Medical Sciences, Mashhad, Iran., Askari VR; Pharmacological Research Center of Medicinal Plants, Mashhad University of Medical Sciences, Azadi Sq, Vakil Abad Highway, Mashhad, 9177948564, Iran. askariv@mums.ac.ir.

Publikováno v: Cardiovascular toxicology [Cardiovasc Toxicol] 2024 Dec; Vol. 24 (12), pp. 1467-1509. Date of Electronic Publication: 2024 Sep 22.

A Scale-Free Approach for False Discovery Rate Control in Generalized Linear Models.

Autor: Dai, Chenguang, Lin, Buyu, Xing, Xin, Liu, Jun S.

Publikováno v: Journal of the American Statistical Association; Sep2023, Vol. 118 Issue 543, p1551-1565, 15p