Identification and Characterization of Cancer Cells That Initiate Metastases to the Brain and Other Organs.

Autor: Berghoff AS; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.; Department of Medicine 1, Medical University of Vienna, Vienna, Austria., Liao Y; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Karreman MA; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Ilhan-Mutlu A; Department of Medicine 1, Medical University of Vienna, Vienna, Austria., Gunkel K; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Sprick MR; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany., Eisen C; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany., Kessler T; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Osswald M; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Wünsche S; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Feinauer M; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Gril B; Women's Malignancies Branch, Laboratory of Pathology, Center for Cancer Research, Biostatistics and Data Management Section, NCI, NIH, Bethesda; Laboratory Animal Sciences Program, SAIC-Frederick, NCI, NIH, Frederick, Maryland., Marmé F; Department of Gynecology and Obstetrics and National Center for Tumor Diseases, University Hospital, Heidelberg, Germany., Michel LL; Department of Gynecology and Obstetrics and National Center for Tumor Diseases, University Hospital, Heidelberg, Germany., Bago-Horvath Z; Department of Pathology, Medical University of Vienna, Vienna, Austria., Sahm F; Department of Neuropathology, Institute of Pathology, Ruprecht-Karls University Heidelberg, Heidelberg, Germany.; Clinical Cooperation Unit Neuropathology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany., Becker N; Division of Biostatistics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Breckwoldt MO; Department of Neuroradiology, University Hospital Heidelberg, Heidelberg, Germany., Solecki G; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Gömmel M; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Huang L; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Rübmann P; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Thome CM; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Ratliff M; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Trumpp A; Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM), Heidelberg, Germany; Division of Stem Cells and Cancer, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany; German Cancer Consortium (DKTK), Heidelberg, Germany., Steeg PS; Women's Malignancies Branch, Laboratory of Pathology, Center for Cancer Research, Biostatistics and Data Management Section, NCI, NIH, Bethesda; Laboratory Animal Sciences Program, SAIC-Frederick, NCI, NIH, Frederick, Maryland., Preusser M; Department of Medicine 1, Medical University of Vienna, Vienna, Austria., Wick W; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany., Winkler F; Clinical Cooperation Unit Neurooncology, German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany. frank.winkler@med.uni-heidelberg.de.; Neurology Clinic and National Center for Tumor Diseases, University Hospital Heidelberg, Heidelberg, Germany.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2021 Apr; Vol. 19 (4), pp. 688-701. Date of Electronic Publication: 2020 Dec 22.

Tryptophan and its metabolites in normal physiology and cancer etiology.

Autor: Perez‐Castro, Lizbeth¹ (AUTHOR), Garcia, Roy¹ (AUTHOR), Venkateswaran, Niranjan¹ (AUTHOR), Barnes, Spencer² (AUTHOR), Conacci‐Sorrell, Maralice^1,3,4 (AUTHOR) maralice.conaccisorrell@utsouthwestern.edu

Publikováno v: FEBS Journal. Jan2023, Vol. 290 Issue 1, p7-27. 21p.

PTX3 mediates the infiltration, migration, and inflammation‐resolving‐polarization of macrophages in glioblastoma.

Autor: Zhang, Hao^1,2 (AUTHOR), Wang, Yifan^1,2,3 (AUTHOR), Zhao, Yihan^1,2,3 (AUTHOR), Liu, Tao^1,2,3 (AUTHOR), Wang, Zeyu^1,2 (AUTHOR), Zhang, Nan⁴ (AUTHOR), Dai, Ziyu^1,2 (AUTHOR), Wu, Wantao^1,2,5 (AUTHOR), Cao, Hui⁶ (AUTHOR), Feng, Songshan^1,2 (AUTHOR), Zhang, Liyang^1,2 (AUTHOR), Cheng, Quan^1,2 (AUTHOR) chengquan@csu.edu.cn, Liu, Zhixiong^1,2 (AUTHOR) zhixiongliu@csu.edu.cn

Publikováno v: CNS Neuroscience & Therapeutics. Nov2022, Vol. 28 Issue 11, p1748-1766. 19p.

TP53 wild-type/PPM1D mutant diffuse intrinsic pontine gliomas are sensitive to a MDM2 antagonist.

Autor: Xu, Cheng^1,2,3 (AUTHOR), Liu, Heng^1,2 (AUTHOR), Pirozzi, Christopher J.^1,2 (AUTHOR), Chen, Lee H.^1,2 (AUTHOR), Greer, Paula K.^1,2 (AUTHOR), Diplas, Bill H.⁴ (AUTHOR), Zhang, Liwei³ (AUTHOR), Waitkus, Matthew S.^2,5 (AUTHOR), He, Yiping^1,2 (AUTHOR) yiping.he@duke.edu, Yan, Hai^1,2 (AUTHOR) hai.yan@duke.edu

Publikováno v: Acta Neuropathologica Communications. 11/3/2021, Vol. 9 Issue 1, p1-12. 12p.

Treatment with the apoptosis inhibitor Asunercept reduces clone sizes in patients with lower risk Myelodysplastic Neoplasms.

Autor: Streuer A; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany. alexander.streuer@medma.uni-heidelberg.de., Jann JC; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Boch T; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Mossner M; Centre for Genomics and Computational Biology, Barts Cancer Institute, London, UK., Riabov V; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Schmitt N; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Altrock E; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Xu Q; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Demmerle M; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Nowak V; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Oblaender J; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Palme I; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Weimer N; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Rapp F; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Metzgeroth G; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Hecht A; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Höger T; Apogenix GmbH, Heidelberg, Germany., Merz C; Apogenix GmbH, Heidelberg, Germany., Hofmann WK; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Nolte F; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany., Nowak D; Department of Hematology and Oncology, Medical Faculty Mannheim of the Heidelberg University, Pettenkoferstr. 22, 68169, Mannheim, Germany.

Publikováno v: Annals of hematology [Ann Hematol] 2024 Apr; Vol. 103 (4), pp. 1221-1233. Date of Electronic Publication: 2024 Feb 27.