Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Thomas van Brussel"'
Autor:
Tatjana Geukens, Maxim De Schepper, Wouter Van Den Bogaert, Karen Van Baelen, Marion Maetens, Anirudh Pabba, Amena Mahdami, Sophia Leduc, Edoardo Isnaldi, Ha-Linh Nguyen, Imane Bachir, Maysam Hajipirloo, Gitte Zels, Josephine Van Cauwenberge, Kristien Borremans, Vincent Vandecaveye, Birgit Weynand, Peter Vermeulen, Eleonora Leucci, Maria Francesca Baietti, George Sflomos, Laura Battista, Cathrin Brisken, Patrick W. B. Derksen, Thijs Koorman, Daan Visser, Colinda L. G. J. Scheele, Daniela S. Thommen, Sigrid Hatse, Sarah-Maria Fendt, Evy Vanderheyden, Thomas Van Brussel, Rogier Schepers, Bram Boeckx, Diether Lambrechts, Giuseppe Marano, Elia Biganzoli, Ann Smeets, Ines Nevelsteen, Kevin Punie, Patrick Neven, Hans Wildiers, François Richard, Giuseppe Floris, Christine Desmedt
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Research on metastatic cancer has been hampered by limited sample availability. Here we present the breast cancer post-mortem tissue donation program UPTIDER and show how it enabled sampling of a median of 31 (range: 5-90) metastases and 5-8
Externí odkaz:
https://doaj.org/article/64acb1b4e34a40a5a3f7576042fa573b
Autor:
Wout De Wispelaere, Daniela Annibali, Sandra Tuyaerts, Julie Messiaen, Asier Antoranz, Gautam Shankar, Nikolina Dubroja, Alejandro Herreros‐Pomares, Regina E. M. Baiden‐Amissah, Marie‐Pauline Orban, Marcello Delfini, Emanuele Berardi, Thomas Van Brussel, Rogier Schepers, Gino Philips, Bram Boeckx, Maria Francesca Baietti, Luigi Congedo, Kiave Yune HoWangYin, Emilie Bayon, Anne‐Sophie Van Rompuy, Eleonora Leucci, Sebastien P. Tabruyn, Francesca Bosisio, Massimiliano Mazzone, Diether Lambrechts, Frédéric Amant
Publikováno v:
Clinical and Translational Medicine, Vol 14, Iss 5, Pp n/a-n/a (2024)
Abstract Background Uterine leiomyosarcomas (uLMS) are aggressive tumours with poor prognosis and limited treatment options. Although immune checkpoint blockade (ICB) has proven effective in some ‘challenging‐to‐treat’ cancers, clinical trial
Externí odkaz:
https://doaj.org/article/96c1f251d0ff4741b236139055f4119b
Autor:
Sarah Cappuyns, Gino Philips, Vincent Vandecaveye, Bram Boeckx, Rogier Schepers, Thomas Van Brussel, Ingrid Arijs, Aurelie Mechels, Ayse Bassez, Francesca Lodi, Joris Jaekers, Halit Topal, Baki Topal, Orian Bricard, Junbin Qian, Eric Van Cutsem, Chris Verslype, Diether Lambrechts, Jeroen Dekervel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract The combination of atezolizumab plus bevacizumab (atezo/bev) has dramatically changed the treatment landscape of advanced HCC (aHCC), achieving durable responses in some patients. Using single-cell transcriptomics, we characterize the intra-
Externí odkaz:
https://doaj.org/article/db4b12030ddd4fd095ec4bcc29c92ddb
Autor:
Baptiste Lamarthée, Jasper Callemeyn, Yannick Van Herck, Asier Antoranz, Dany Anglicheau, Patrick Boada, Jan Ulrich Becker, Tim Debyser, Frederik De Smet, Katrien De Vusser, Maëva Eloudzeri, Amelie Franken, Wilfried Gwinner, Priyanka Koshy, Dirk Kuypers, Diether Lambrechts, Pierre Marquet, Virginie Mathias, Marion Rabant, Minnie M. Sarwal, Aleksandar Senev, Tara K. Sigdel, Ben Sprangers, Olivier Thaunat, Claire Tinel, Thomas Van Brussel, Amaryllis Van Craenenbroeck, Elisabet Van Loon, Thibaut Vaulet, Francesca Bosisio, Maarten Naesens
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-22 (2023)
Abstract Rejection remains the main cause of premature graft loss after kidney transplantation, despite the use of potent immunosuppression. This highlights the need to better understand the composition and the cell-to-cell interactions of the allore
Externí odkaz:
https://doaj.org/article/7390314e25494b48965250724b83fa09
Autor:
Robert D. Morgan, Cristina Ferreras, Isabel Peset, Egle Avizienyte, Andrew G. Renehan, Richard J. Edmondson, Alexander D. Murphy, Shibani Nicum, Thomas Van Brussel, Andrew R. Clamp, Diether Lambrechts, Cong Zhou, Gordon C. Jayson
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Highlights Tissue microarrays and germline DNA from women recruited to the phase 3 trial, ICON7, underwent quantitative immunofluorescence for c-MET/VEGFR-2 co-expression and genetic sequencing for single nucleotide polymorphisms (SNPs) VEGF-pathway
Externí odkaz:
https://doaj.org/article/1954157b03284a32b79f59f1c52385eb
Autor:
Stéphanie Humblet-Baron, Kristiaan Nackaerts, Johan Vansteenkiste, Diether Lambrechts, Robin Vos, Els Wauters, Jonas Yserbyt, Christophe Dooms, Dries Testelmans, Amelie Franken, Pierre Van Mol, Sam Vanmassenhove, Elena Donders, Rogier Schepers, Thomas Van Brussel, Nico De Crem, Walter De Wever
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 9 (2022)
Background Immune checkpoint inhibitor (ICI)-related pneumonitis is the most frequent fatal immune-related adverse event associated with programmed cell death protein-1/programmed death ligand-1 blockade. The pathophysiology however remains largely u
Externí odkaz:
https://doaj.org/article/f0bd6d17904e4e53b66c0bf815ab4299
Autor:
Aurora Gómez-Vecino, Roberto Corchado-Cobos, Adrián Blanco-Gómez, Natalia García-Sancha, Sonia Castillo-Lluva, Ana Martín-García, Marina Mendiburu-Eliçabe, Carlos Prieto, Sara Ruiz-Pinto, Guillermo Pita, Alejandro Velasco-Ruiz, Carmen Patino-Alonso, Purificación Galindo-Villardón, María Linarejos Vera-Pedrosa, José Jalife, Jian-Hua Mao, Guillermo Macías de Plasencia, Andrés Castellanos-Martín, María del Mar Sáez-Freire, Susana Fraile-Martín, Telmo Rodrigues-Teixeira, Carmen García-Macías, Julie Milena Galvis-Jiménez, Asunción García-Sánchez, María Isidoro-García, Manuel Fuentes, María Begoña García-Cenador, Francisco Javier García-Criado, Juan Luis García-Hernández, María Ángeles Hernández-García, Juan Jesús Cruz-Hernández, César Augusto Rodríguez-Sánchez, Alejandro Martín García-Sancho, Estefanía Pérez-López, Antonio Pérez-Martínez, Federico Gutiérrez-Larraya, Antonio J. Cartón, José Ángel García-Sáenz, Ana Patiño-García, Miguel Martín, Teresa Alonso-Gordoa, Christof Vulsteke, Lieselot Croes, Sigrid Hatse, Thomas Van Brussel, Diether Lambrechts, Hans Wildiers, Hang Chang, Marina Holgado-Madruga, Anna González-Neira, Pedro L. Sánchez, Jesús Pérez Losada
Publikováno v:
Cells, Vol 12, Iss 15, p 1956 (2023)
Cardiotoxicity due to anthracyclines (CDA) affects cancer patients, but we cannot predict who may suffer from this complication. CDA is a complex trait with a polygenic component that is mainly unidentified. We propose that levels of intermediate mol
Externí odkaz:
https://doaj.org/article/30117a66c9fb4e32901af4d0a0a24d13
Autor:
Abbas Jariani, Lieselotte Vermeersch, Bram Cerulus, Gemma Perez-Samper, Karin Voordeckers, Thomas Van Brussel, Bernard Thienpont, Diether Lambrechts, Kevin J Verstrepen
Publikováno v:
eLife, Vol 9 (2020)
Current methods for single-cell RNA sequencing (scRNA-seq) of yeast cells do not match the throughput and relative simplicity of the state-of-the-art techniques that are available for mammalian cells. In this study, we report how 10x Genomics’ drop
Externí odkaz:
https://doaj.org/article/0b040c888f3f4dfe9cb709417cd5faa4
Autor:
Alejandro Velasco-Ruiz, Rocio Nuñez-Torres, Guillermo Pita, Hans Wildiers, Diether Lambrechts, Sigrid Hatse, Danielle Delombaerde, Thomas Van Brussel, M. Rosario Alonso, Nuria Alvarez, Belen Herraez, Christof Vulsteke, Pilar Zamora, Teresa Lopez-Fernandez, Anna Gonzalez-Neira
Publikováno v:
Pharmaceutics, Vol 13, Iss 11, p 1942 (2021)
Anthracyclines are among the most used chemotherapeutic agents in breast cancer (BC). However their use is hampered by anthracycline-induced cardiotoxicity (AIC). The currently known clinical and genetic risk factors do not fully explain the observed
Externí odkaz:
https://doaj.org/article/fc41170d71e949d6a10cde030ad32cba
Autor:
Baptiste Lamarthée, Jasper Callemeyn, Yannick Van Herck, Asier Antoranz, Dany Anglicheau, Jan Ulrich Becker, Tim Debyser, Frederik De Smet, Katrien De Vusser, Maëva Eloudzeri, Amelie Franken, Wilfried Gwinner, Priyanka Koshy, Dirk Kuypers, Diether Lambrechts, Pierre Marquet, Marion Rabant, Ben Sprangers, Claire Tinel, Thomas Van Brussel, Amaryllis Van Craenenbroeck, Elisabet Van Loon, Thibaut Vaulet, Francesca Bosisio, Maarten Naesens
Rejection remains the main cause of premature graft loss after kidney transplantation, despite the use of potent immunosuppression. This highlights the need to better understand the composition and the interactions of the alloreactive inflammatory in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99e564ef5092211575391097fe221c5d
https://doi.org/10.1101/2022.07.07.22276374
https://doi.org/10.1101/2022.07.07.22276374
