Výsledky vyhledávání - "Thomas Zwergel"

A new serial transfer explant cell culture system for human prostatic cancer tissues preventing selection toward diploid cells

Autor: Thomas Zwergel, Heike Schorr, Bernd Wullich, Hacer Kakirman, Gerhard Unteregger

Publikováno v: Cancer Genetics and Cytogenetics. 101:16-23

An improved explant cell culture technique to avoid selection of prostatic adenocarcinoma cells toward diploid cells is described. This method is based on 1) histologically characterized tissue explants, 2) the use of polyethylenteraphthalate (PET) m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7ea4cf4f07eb51bdd735acdd8eb411
https://doi.org/10.1016/s0165-4608(97)00062-9

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Curriculum in Urology

Autor: D. C. S. Gough, Yukio Kageyama, Hiroyuki Oshima, J.H.M. Blom, Kazunori Kihara, Gunnar Kratz, F. Algaba, A. Orsola, A. Webster, D. van den Ouden, J. Vicente, M.C. Michel, F. Wuyts, L. Baert, J. McEwen, J. Palou, T. O. Henkel, K. D’Hauwers, B. Xavier, Iwao Fukui, Andrea Haitel, T. Moreland, W. Oosterlinck, Christoph H. Klingler, A.H.V.C. de Spiegeleer, Christian Stock, Jean-Marie de Meyer, Thomas Zwergel, Aaltomaa Sirpa, T. Tammela, J. Salvador, Gertraud Heinz-Peer, Michael Marberger, J.B. Anderson, S. Sys, A.V. Kaisary, S. Buyle, Kieran J. O’Flynn, Yasuhisa Fujii, Volker Rohde, Thomas Frede, Ulrike Zwergel, C. Bangma, Bernd Wullich, Peter Alken, Toshihiko Tsujii, C.J. Tyrrell, Jens Rassweiler, Jan Eldh, Richard J. Brough, P. Iversen, C. de Mey, Carl-Johan Gustafson, Armin Pycha, Ala-Opas Martti, J.J. Wyndaele, Kazuhiro Ishizaka, M. Chamberlain, Janet Fishwick, Satoru Kawakami, G. Blackledge, Ulrike Lindenmeir

Publikováno v: European Urology. 33:512-521

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::10a3ff14f7af4ecf5092c167a2156903
https://doi.org/10.1159/000019647

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Androgen Receptor Expression, Proliferation Index and Aneuploidy in Tissue Explant Cultures Derived Prostate Carcinoma Cells Co-Cultivated on Membranes

Autor: Hacer Kakirman, Thomas Zwergel, Gerhard Unteregger, Volker Rohde, Bernd Wullich

Publikováno v: European Urology. 33:414-423

An improved explant cell culture technique to avoid selection of prostatic adenocarcinoma cells toward diploid cells is described.21 prostatic carcinoma specimens which were obtained from 13 primary prostatic adenocarcinomas after radical prostatecto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27e78a2cfeb6d8a8696c93e4368f233
https://doi.org/10.1159/000019628

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Comprehensive genotypic analysis of human prostate cancer cell lines and sublines derived from metastases after orthotopic implantation in nude mice

Autor: Claudia Götz, Christine Andres, Thomas Zwergel, Michael Stoeckle, Bernd Wullich, Jörn Kamradt, Gerhard Unteregger, Ramona Lensch, Axel Bex, Jan Lehmann

Publikováno v: International journal of oncology. 21(4)

We recently reported on a prostate cancer progression model which was based on repeated orthotopic implantation of human prostate cancer cell lines into athymic nude mice leading to an increase of tumor cell aggressiveness. To assess progression-asso

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2240438f25994ff751faf9cde85352c
https://pubmed.ncbi.nlm.nih.gov/12239607

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Genetic heterogeneity of prostatic carcinoma-derived cell lines as emphasized by DNA fingerprinting

Autor: Thomas Zwergel, Klaus-Dieter Zang, Bernd Wullich, Gerhard Unteregger, Alexander Christmann, Stephanie Bettink

Publikováno v: Electrophoresis. 13:644-646

To investigate genetic heterogeneity during in vitro cultivation of human prostatic carcinomas following radical prostatectomy we performed DNA fingerprinting using the digoxygenin-labeled probes (GACA)4 and (GTG)5. DNA was isolated from fresh materi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd499232d969f0f11f38d3034c24aed
https://doi.org/10.1002/elps.11501301133

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Novel amplification unit at chromosome 3q25-q27 in human prostate cancer

Autor: Axel Bex, Thomas Zwergel, Volker Rohde, Michael Stoeckle, Margitta Retz, Bernd Wullich, Emmanuel Zimmer, H.-P. Sattler, Eckhart Meese, Ramona Lensch, Helmut Bonkhoff

Publikováno v: The Prostate. 45(3)

BACKGROUND In prostate carcinoma, amplification of the genes c-MYC, Her2/NEU, and the androgen receptor gene has been documented, with gene amplification being related to progressive tumor growth. Recently, using comparative genomic hybridization (CG

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58fe4be75e15643cea3e5e1ba54b480
https://pubmed.ncbi.nlm.nih.gov/11074522

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Two different forms of p53 localized differently within cells of urogenital tumours

Autor: Helga Selter, Mathias Montenarh, Thomas Zwergel, Zacharia Teleb, Gerhard Unteregger, Jens Benninghoff, Bernd Wullich, Sabine Kartarius

Publikováno v: Cancer letters. 144(1)

We analyzed the subcellular localization of p53 in prostate and bladder carcinoma cells. Using laser scanning microscopy and PAb1620, a monoclonal antibody recognizing the wildtype conformation of p53, and another monoclonal antibody directed against

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d42846c9c16a7b1aee8a23b28e342d8
https://pubmed.ncbi.nlm.nih.gov/10503878

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Long-term results following transurethral resection of the prostate

Autor: Ulrike Lindenmeir, Thomas Zwergel, Ulrike Zwergel, Bernd Wullich, Volker Rohde

Publikováno v: European urology. 33(5)

Two subsets of a single-center study population with benign prostatic hyperplasia (n(1) = 232; n(2) = 214) undergoing transurethral resection (TUR) of the prostate (TURP 1979 and 1995) entered a retrospective study designed to examine the long-term f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc5dea6a63e39e5e5cf4734b4d0bad5
https://pubmed.ncbi.nlm.nih.gov/9643667

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Selection toward diploid cells in prostatic carcinoma derived cell cultures

Autor: Ralf Ketter, Konstantinos Romanakis, Klaus-Dieter Zang, Thomas Zwergel, Gerhard Unteregger, Bernd Wullich, Manfred Ziegler

Publikováno v: The Prostate. 28(6)

For elucidation of the growth-regulatory mechanisms in prostatic carcinoma, in vitro investigations on prostatic cell cultures are required. However, one major problem of cell culturing is the selection of particular cell types such that the cell lin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47674ef18060c3c042c988d9ee2bd643
https://pubmed.ncbi.nlm.nih.gov/8650073

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