Zobrazeno 1 - 10
of 38
pro vyhledávání: '"Thomas Zwergel"'
Publikováno v:
The Prostate. 39:79-86
BACKGROUND Despite intensive studies over many years, there is only limited knowledge on the genetic changes underlying the development and progression of prostate cancer. No specific prostate carcinoma-related genetic event has yet been identified.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a644f34555745f1b24696916bfa015
https://doi.org/10.1002/(sici)1097-0045(19990501)39:2<79::aid-pros1>3.0.co
https://doi.org/10.1002/(sici)1097-0045(19990501)39:2<79::aid-pros1>3.0.co
Publikováno v:
Cancer Genetics and Cytogenetics. 101:16-23
An improved explant cell culture technique to avoid selection of prostatic adenocarcinoma cells toward diploid cells is described. This method is based on 1) histologically characterized tissue explants, 2) the use of polyethylenteraphthalate (PET) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e7ea4cf4f07eb51bdd735acdd8eb411
https://doi.org/10.1016/s0165-4608(97)00062-9
https://doi.org/10.1016/s0165-4608(97)00062-9
Autor:
D. C. S. Gough, Yukio Kageyama, Hiroyuki Oshima, J.H.M. Blom, Kazunori Kihara, Gunnar Kratz, F. Algaba, A. Orsola, A. Webster, D. van den Ouden, J. Vicente, M.C. Michel, F. Wuyts, L. Baert, J. McEwen, J. Palou, T. O. Henkel, K. D’Hauwers, B. Xavier, Iwao Fukui, Andrea Haitel, T. Moreland, W. Oosterlinck, Christoph H. Klingler, A.H.V.C. de Spiegeleer, Christian Stock, Jean-Marie de Meyer, Thomas Zwergel, Aaltomaa Sirpa, T. Tammela, J. Salvador, Gertraud Heinz-Peer, Michael Marberger, J.B. Anderson, S. Sys, A.V. Kaisary, S. Buyle, Kieran J. O’Flynn, Yasuhisa Fujii, Volker Rohde, Thomas Frede, Ulrike Zwergel, C. Bangma, Bernd Wullich, Peter Alken, Toshihiko Tsujii, C.J. Tyrrell, Jens Rassweiler, Jan Eldh, Richard J. Brough, P. Iversen, C. de Mey, Carl-Johan Gustafson, Armin Pycha, Ala-Opas Martti, J.J. Wyndaele, Kazuhiro Ishizaka, M. Chamberlain, Janet Fishwick, Satoru Kawakami, G. Blackledge, Ulrike Lindenmeir
Publikováno v:
European Urology. 33:512-521
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10a3ff14f7af4ecf5092c167a2156903
https://doi.org/10.1159/000019647
https://doi.org/10.1159/000019647
Publikováno v:
European Urology. 33:414-423
An improved explant cell culture technique to avoid selection of prostatic adenocarcinoma cells toward diploid cells is described.21 prostatic carcinoma specimens which were obtained from 13 primary prostatic adenocarcinomas after radical prostatecto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27e78a2cfeb6d8a8696c93e4368f233
https://doi.org/10.1159/000019628
https://doi.org/10.1159/000019628
Autor:
Claudia Götz, Christine Andres, Thomas Zwergel, Michael Stoeckle, Bernd Wullich, Jörn Kamradt, Gerhard Unteregger, Ramona Lensch, Axel Bex, Jan Lehmann
Publikováno v:
International journal of oncology. 21(4)
We recently reported on a prostate cancer progression model which was based on repeated orthotopic implantation of human prostate cancer cell lines into athymic nude mice leading to an increase of tumor cell aggressiveness. To assess progression-asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2240438f25994ff751faf9cde85352c
https://pubmed.ncbi.nlm.nih.gov/12239607
https://pubmed.ncbi.nlm.nih.gov/12239607
Autor:
Thomas Zwergel, Klaus-Dieter Zang, Bernd Wullich, Gerhard Unteregger, Alexander Christmann, Stephanie Bettink
Publikováno v:
Electrophoresis. 13:644-646
To investigate genetic heterogeneity during in vitro cultivation of human prostatic carcinomas following radical prostatectomy we performed DNA fingerprinting using the digoxygenin-labeled probes (GACA)4 and (GTG)5. DNA was isolated from fresh materi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecd499232d969f0f11f38d3034c24aed
https://doi.org/10.1002/elps.11501301133
https://doi.org/10.1002/elps.11501301133
Autor:
Axel Bex, Thomas Zwergel, Volker Rohde, Michael Stoeckle, Margitta Retz, Bernd Wullich, Emmanuel Zimmer, H.-P. Sattler, Eckhart Meese, Ramona Lensch, Helmut Bonkhoff
Publikováno v:
The Prostate. 45(3)
BACKGROUND In prostate carcinoma, amplification of the genes c-MYC, Her2/NEU, and the androgen receptor gene has been documented, with gene amplification being related to progressive tumor growth. Recently, using comparative genomic hybridization (CG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a58fe4be75e15643cea3e5e1ba54b480
https://pubmed.ncbi.nlm.nih.gov/11074522
https://pubmed.ncbi.nlm.nih.gov/11074522
Autor:
Helga Selter, Mathias Montenarh, Thomas Zwergel, Zacharia Teleb, Gerhard Unteregger, Jens Benninghoff, Bernd Wullich, Sabine Kartarius
Publikováno v:
Cancer letters. 144(1)
We analyzed the subcellular localization of p53 in prostate and bladder carcinoma cells. Using laser scanning microscopy and PAb1620, a monoclonal antibody recognizing the wildtype conformation of p53, and another monoclonal antibody directed against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d42846c9c16a7b1aee8a23b28e342d8
https://pubmed.ncbi.nlm.nih.gov/10503878
https://pubmed.ncbi.nlm.nih.gov/10503878
Publikováno v:
European urology. 33(5)
Two subsets of a single-center study population with benign prostatic hyperplasia (n(1) = 232; n(2) = 214) undergoing transurethral resection (TUR) of the prostate (TURP 1979 and 1995) entered a retrospective study designed to examine the long-term f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfc5dea6a63e39e5e5cf4734b4d0bad5
https://pubmed.ncbi.nlm.nih.gov/9643667
https://pubmed.ncbi.nlm.nih.gov/9643667
Autor:
Ralf Ketter, Konstantinos Romanakis, Klaus-Dieter Zang, Thomas Zwergel, Gerhard Unteregger, Bernd Wullich, Manfred Ziegler
Publikováno v:
The Prostate. 28(6)
For elucidation of the growth-regulatory mechanisms in prostatic carcinoma, in vitro investigations on prostatic cell cultures are required. However, one major problem of cell culturing is the selection of particular cell types such that the cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47674ef18060c3c042c988d9ee2bd643
https://pubmed.ncbi.nlm.nih.gov/8650073
https://pubmed.ncbi.nlm.nih.gov/8650073