Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Thomas Zabawa"'
Publikováno v:
Expert Review of Anti-infective Therapy. 16:513-522
Infections caused by antibiotic-resistant pathogens, particularly Gram-negative bacteria, have become increasingly challenging to successfully treat. The beta-lactam antibiotic subclass, the carbapenems, have proven valuable for the treatment of such
Publikováno v:
Medicinal Chemistry Reviews ISBN: 9780996293235
Medicinal Chemistry Reviews
Medicinal Chemistry Reviews
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::adcbd007ab70f46faaef3aca8dd590ae
https://doi.org/10.29200/acsmedchemrev-v51.ch15
https://doi.org/10.29200/acsmedchemrev-v51.ch15
Publikováno v:
Current opinion in microbiology. 33
Infections caused by antibiotic-resistant pathogens, particularly Gram-negative bacteria, represent significant treatment challenges for physicians resulting in high rates of morbidity and mortality. The outer membrane of Gram-negative bacteria acts
Autor:
Dominic Hoepfner, Simona Cotesta, Sven Schuierer, Neil S. Ryder, John A. Tallarico, Jianshi Tao, David Estoppey, Daryl L. Richie, Ralph Riedl, Katherine V. Thompson, Christian Studer, Jessica A. Sexton, Thomas Zabawa, Vivian Prindle, Thomas Aust, Joseph Drumm, Nicole Hartmann, Jürg Eichenberger, N. Rao Movva
Publikováno v:
Antimicrobial agents and chemotherapy. 57(5)
High-throughput phenotypic screening against the yeast Saccharomyces cerevisiae revealed a series of triazolopyrimidine-sulfonamide compounds with broad-spectrum antifungal activity, no significant cytotoxicity, and low protein binding. To elucidate