Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Thomas Wiegert"'
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-14 (2019)
Abstract Background Heterologous gene expression is well established for various prokaryotic model systems. However, low yield, incorrect folding and instability still impede the production of soluble, bioactive proteins. To improve protein productio
Externí odkaz:
https://doaj.org/article/65f87d8159ea4854823e6a1e9711f9e7
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e48471 (2012)
Bacteria employ extracytoplasmic function (ECF) sigma factors for their responses to environmental stresses. Despite intensive research, the molecular dissection of ECF sigma factor regulons has remained a major challenge due to overlaps in the ECF s
Externí odkaz:
https://doaj.org/article/f2993f4834a0451394b46fd7377a7ce1
Publikováno v:
Food Packaging and Shelf Life. 28:100666
Several packaging solutions for the food industry have to consider the harmful effects of oxygen within a pack for packaging of oxygen sensitive foods. This issue can be addressed by using oxygen scavengers. However, in adverse cases, conventional ox
Publikováno v:
Microbial Cell Factories, Vol 18, Iss 1, Pp 1-14 (2019)
Microbial Cell Factories
Microbial Cell Factories
Background Heterologous gene expression is well established for various prokaryotic model systems. However, low yield, incorrect folding and instability still impede the production of soluble, bioactive proteins. To improve protein production with th
Publikováno v:
New Zealand Journal of Forestry Science. 46
Progesterone 5β-reductases (P5sRs) catalyse one step in the stereospecific biosynthesis of cardenolides (potent repellents of herbivores and pharmaceutical stimulants of disordered heart muscle cells). They were originally discovered in the genus Di
Autor:
Thomas Wiegert
Publikováno v:
Bacterial Signaling
Publikováno v:
Molecular Microbiology. 74:1412-1426
Summary Stress-induced degradation of the Bacillus subtilis anti-sigma factor RsiW results in the induction of genes controlled by the extracytoplasmic function sigma factor σW. RsiW is cleaved by the mechanism of regulated intramembrane proteolysis
Publikováno v:
Applied and environmental microbiology, 75(23), 7356-7364. AMER SOC MICROBIOLOGY
Essential membrane proteins are generally recognized as relevant potential drug targets due to their exposed localization in the cell envelope. Unfortunately, high-level production of membrane proteins for functional and structural analyses is often
Autor:
Thomas Wiegert, Janine Heinrich
Publikováno v:
Molecular Microbiology. 62:566-579
Genes of Bacillus subtilis controlled by the alternative extracytoplasmic function family sigma factor sigmaW constitute an antibiosis regulon. Its activity is modulated by RsiW, a transmembrane anti-sigma factor that sequesters and inactivates sigma
Publikováno v:
FEMS Microbiology Letters. 253:221-229
The chromosome of Bacillus subtilis codes for seven extracytoplasmic function sigma factors the activity of which is modulated normally by a cognate anti-sigma factor. While inducing factors and genes for four of them (sigma(M), sigma(W), sigma(X), a