Zobrazeno 1 - 10
of 266
pro vyhledávání: '"Thomas Wieder"'
Autor:
Ziwen Zheng, Thomas Wieder, Bernhard Mauerer, Luisa Schäfer, Rebecca Kesselring, Heidi Braumüller
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11673 (2023)
Therapeutic options for metastatic colorectal cancer (mCRC) are very limited, and the prognosis using combination therapy with a chemotherapeutic drug and a targeted agent, e.g., epidermal growth factor receptor or tyrosine kinase, remains poor. Ther
Externí odkaz:
https://doaj.org/article/7e645e3cfc2c472bb7a2a4f05389235e
Autor:
Ellen Brenner, Barbara F. Schörg, Fatima Ahmetlić, Thomas Wieder, Franz Joachim Hilke, Nadine Simon, Christopher Schroeder, German Demidov, Tanja Riedel, Birgit Fehrenbacher, Martin Schaller, Andrea Forschner, Thomas Eigentler, Heike Niessner, Tobias Sinnberg, Katharina S. Böhm, Nadine Hömberg, Heidi Braumüller, Daniel Dauch, Stefan Zwirner, Lars Zender, Dominik Sonanini, Albert Geishauser, Jürgen Bauer, Martin Eichner, Katja J. Jarick, Andreas Beilhack, Saskia Biskup, Dennis Döcker, Dirk Schadendorf, Leticia Quintanilla-Martinez, Bernd J. Pichler, Manfred Kneilling, Ralph Mocikat, Martin Röcken
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-19 (2020)
The growth of cancer cells can be stably arrested by cytokine-induced senescence. Here, the authors show that cancers with defects in senescence-inducing cell cycle regulator pathways are resistant to immune checkpoint blockade.
Externí odkaz:
https://doaj.org/article/ffeefb0c18174583b0c353a1c64a24f9
Autor:
Heidi Braumüller, Bernhard Mauerer, Johanna Andris, Christopher Berlin, Thomas Wieder, Rebecca Kesselring
Publikováno v:
Cells, Vol 12, Iss 1, p 138 (2022)
Colorectal cancer (CRC) is one of the most frequent tumor entities worldwide with only limited therapeutic options. CRC is not only a genetic disease with several mutations in specific oncogenes and/or tumor suppressor genes such as APC, KRAS, PIC3CA
Externí odkaz:
https://doaj.org/article/41ea724702614176aefd57980ed8b55a
IFN-γ and TNF Induce Senescence and a Distinct Senescence-Associated Secretory Phenotype in Melanoma
Autor:
Lorenzo Homann, Maximilian Rentschler, Ellen Brenner, Katharina Böhm, Martin Röcken, Thomas Wieder
Publikováno v:
Cells, Vol 11, Iss 9, p 1514 (2022)
Immune checkpoint blockade (ICB) therapy is a central pillar of melanoma treatment leading to durable response rates. Important mechanisms of action of ICB therapy include disinhibition of CD4+ and CD8+ T cells. Stimulated CD4+ T helper 1 cells secre
Externí odkaz:
https://doaj.org/article/dccbe97fd16e4b11b220ea6fe519faaf
Publikováno v:
Cells, Vol 11, Iss 3, p 503 (2022)
Human erythrocytes are organelle-free cells packaged with iron-containing hemoglobin, specializing in the transport of oxygen. With a total number of approximately 25 trillion cells per individual, the erythrocyte is the most abundant cell type not o
Externí odkaz:
https://doaj.org/article/cb3f55088682445bb411c1cc3b98a15a
Autor:
Maximilian Rentschler, Yan Chen, Jana Pahl, Laura Soria-Martinez, Heidi Braumüller, Ellen Brenner, Oliver Bischof, Martin Röcken, Thomas Wieder
Publikováno v:
Cellular Physiology and Biochemistry, Vol 51, Iss 3, Pp 1103-1118 (2018)
Background/Aims: Cellular senescence, or permanent growth arrest, is known as an effective tumor suppressor mechanism that can be induced by different stressors, such as oncogenes, chemotherapeutics or cytokine cocktails. Previous studies demonstrate
Externí odkaz:
https://doaj.org/article/4340da49bee64918abab59a9f9c4ee9d
Autor:
Mehrdad Ghashghaeinia, Mauro Carlos Wesseling, Elena Ramos, Polina Petkova-Kirova, Sabrina Waibel, Elisabeth Lang, Rosi Bissinger, Kossai Alzoubi, Baerbel Edelmann, Zohreh Hosseinzadeh, Peter Dreischer, Azam Shahvaroughi-Farahani, Ulrich Mrowietz, Martin Köberle, Lars Kaestner, Ingolf Bernhardt, Antonio Martínez-Ruiz, Thomas Wieder, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 42, Iss 5, Pp 1985-1998 (2017)
Background and Purpose: The high potency antipsychotic drug trifluoperazine (10-[3-(4-methyl-1-piperazinyl)-propyl]-2-(trifluoromethyl)-(10)H-phenothiazine dihydrochloride; TFP) may either counteract or promote suicidal cell death or apoptosis. Simil
Externí odkaz:
https://doaj.org/article/0fc24e8529b841b787166088b52cddf1
Autor:
Mehrdad Ghashghaeinia, Judith C. Cluitmans, Mahmoud Toulany, Mohammad Saki, Martin Köberle, Elisabeth Lang, Peter Dreischer, Tilo Biedermann, Michael Duszenko, Florian Lang, Giel J. Bosman, Thomas Wieder
Publikováno v:
Cellular Physiology and Biochemistry, Vol 32, Iss 4, Pp 801-813 (2013)
Background/Aims: Erythrocytes may enter eryptosis, a suicidal death characterized by cell shrinkage and phosphatidylserine exposure at the erythrocyte outer membrane. Susceptibility to eryptosis is enhanced in aged erythrocytes and stimulated by NFκ
Externí odkaz:
https://doaj.org/article/d37cd52c31464243af3089c45f1fe8ac
Autor:
Thomas Wieder, Élisabeth Bonnet-Pineau
Publikováno v:
EchoGéo, Vol 46
Externí odkaz:
https://doaj.org/article/1873b270d74942258b8cb1ab15808d22
Autor:
Sandrine Kott, Thomas Wieder
Publikováno v:
Contemporary European History. 32:3-8
In the slipstream of the Black Lives Matter movement in the United States, there has been a global mobilisation around monuments and statues of famous figures involved in the slave trade and European colonial conquest. In former colonial states – s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abef6563e6c1d195e2a2d02c464fa7d6
https://doi.org/10.1017/s0960777322000467
https://doi.org/10.1017/s0960777322000467