Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Thomas Weidemann"'
Autor:
Frederik Steiert, Peter Schultz, Siegfried Höfinger, Thomas D. Müller, Petra Schwille, Thomas Weidemann
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
It is challenging to approach protein structures in living cells. Here the authors investigate Interleukin-4 receptor alpha, which has a noncanonical amino acid incorporated at different locations, and see that evaluating click efficiency with calibr
Externí odkaz:
https://doaj.org/article/15d091ccc2a44bd68688832efcdaf1be
Publikováno v:
PLoS Biology, Vol 17, Iss 3, p e3000057 (2019)
Cells in developing organisms are subjected to particular mechanical forces that shape tissues and instruct cell fate decisions. How these forces are sensed and transmitted at the molecular level is therefore an important question, one that has mainl
Externí odkaz:
https://doaj.org/article/5bd4e75870054cb585c66f36ea8231a2
Autor:
Olena Pylypenko, Tobias Welz, Janine Tittel, Martin Kollmar, Florian Chardon, Gilles Malherbe, Sabine Weiss, Carina Ida Luise Michel, Annette Samol-Wolf, Andreas Till Grasskamp, Alistair Hume, Bruno Goud, Bruno Baron, Patrick England, Margaret A Titus, Petra Schwille, Thomas Weidemann, Anne Houdusse, Eugen Kerkhoff
Publikováno v:
eLife, Vol 5 (2016)
There is growing evidence for a coupling of actin assembly and myosin motor activity in cells. However, mechanisms for recruitment of actin nucleators and motors on specific membrane compartments remain unclear. Here we report how Spir actin nucleato
Externí odkaz:
https://doaj.org/article/c2c1af684db44be18ca98b689ff18474
Publikováno v:
Biophysical Journal
Fluorescent proteins (FPs) feature complex photophysical behavior that must be considered when studying the dynamics of fusion proteins in model systems and live cells. In this work, we characterize mNeonGreen (mNG), a recently introduced FP from the
Publikováno v:
PLoS Biology
PLoS Biology, Public Library of Science, 2019, 17 (3), pp.e3000057. ⟨10.1371/journal.pbio.3000057⟩
PLoS Biology, 2019, 17 (3), pp.e3000057. ⟨10.1371/journal.pbio.3000057⟩
PLoS Biology, Vol 17, Iss 3, p e3000057 (2019)
PLoS Biology, Public Library of Science, 2019, 17 (3), pp.e3000057. ⟨10.1371/journal.pbio.3000057⟩
PLoS Biology, 2019, 17 (3), pp.e3000057. ⟨10.1371/journal.pbio.3000057⟩
PLoS Biology, Vol 17, Iss 3, p e3000057 (2019)
Cells in developing organisms are subjected to particular mechanical forces that shape tissues and instruct cell fate decisions. How these forces are sensed and transmitted at the molecular level is therefore an important question, one that has mainl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfa277b5f234c61dbbbec7a864a65118
https://hal.archives-ouvertes.fr/hal-02368074/document
https://hal.archives-ouvertes.fr/hal-02368074/document
Autor:
Beat Ludin, Thomas Weidemann, Martin Hintersteiner, Manfred Auer, Nhan T. Pham, Wolf Heusermann
Publikováno v:
ACS Combinatorial Science. 18:209-219
The increasing involvement of academic institutions and biotech companies in drug discovery calls for cost-effective methods to identify new bioactive molecules. Affinity-based on-bead screening of combinatorial one-bead one-compound libraries combin
Autor:
Thomas Weidemann, Christian Bökel, Martin Hintersteiner, Kristina Kurgonaite, Petra Schwille, Hetvi Gandhi, Remigiusz Worch
Publikováno v:
Biophysical Journal. 107:2515-2527
It has long been established that dimerization of Interleukin-4 receptor (IL-4R) subunits is a pivotal step for JAK/STAT signal transduction. However, ligand-induced complex formation at the surface of living cells has been challenging to observe. He
Autor:
Axel Schambach, Peter N. Robinson, Stefan Mundlos, Lela Kardava, Eric P. Hanson, Peter Krawitz, Gulbu Uzel, Jacek Puchałka, Ulrich Baumann, Thomas Weidemann, Hans Kreipe, Daniel Kotlarz, Jana Diestelhorst, Christoph Klein, Roland Jacobs, Eva-Doreen Pfister, Jochen Hecht, Christian Braun, Monica G. Lawrence, E. Michael Gertz, Dietmar Pfeifer, Susan Moir, Natalia Ziętara, Petra Schwille, Alejandro A. Schäffer, Joshua D. Milner
Publikováno v:
The Journal of Experimental Medicine
A primary immunodeficiency syndrome caused by loss-of-function mutations in the IL-21 receptor exhibits impaired B, T, and NK cell function.
Primary immunodeficiencies (PIDs) represent exquisite models for studying mechanisms of human host defen
Primary immunodeficiencies (PIDs) represent exquisite models for studying mechanisms of human host defen
Autor:
Eugen Kerkhoff, Sabine Weiss, Andreas T. Grasskamp, Alistair N. Hume, Martin Kollmar, Thomas Weidemann, Olena Pylypenko, Bruno Baron, Margaret A. Titus, Janine Tittel, Annette Samol-Wolf, Anne Houdusse, Tobias Welz, Florian Chardon, Gilles Malherbe, Patrick England, Bruno Goud, Carina Ida Luise Michel, Petra Schwille
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3a0eace7860e95d8396b255ca9d666
https://doi.org/10.7554/elife.17523.023
https://doi.org/10.7554/elife.17523.023