Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Thomas Wegleiter"'
Autor:
Marlen Knobloch, Gregor-Alexander Pilz, Bart Ghesquière, Werner J. Kovacs, Thomas Wegleiter, Darcie L. Moore, Martina Hruzova, Nicola Zamboni, Peter Carmeliet, Sebastian Jessberger
Publikováno v:
Cell Reports, Vol 20, Iss 9, Pp 2144-2155 (2017)
Hippocampal neurogenesis is important for certain forms of cognition, and failing neurogenesis has been implicated in neuropsychiatric diseases. The neurogenic capacity of hippocampal neural stem/progenitor cells (NSPCs) depends on a balance between
Externí odkaz:
https://doaj.org/article/ec129b5d71fa47c29483cc78941eecb4
Autor:
Iliana Mebert, Dominik Kollegger, Pawel Pelczar, Thomas Wegleiter, Adriano Molteni, Daniel Gonzalez-Bohorquez, Kilian Buthey, Sebastian Jessberger, Martina Hruzova, Muhammad Khadeesh bin Imtiaz, Andrin Abegg
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
PNAS
PNAS
Significance Neural stem cells (NSCs) generate neurons and glia throughout life. Using global S-acylation profiling in NSCs, we identified BMPR1a, a main driver of embryonic and postnatal development to be S-acylated. We showed that BMPR1a is S-acyla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23a40ac6d6a7fcb0120fe527fe672285
https://doi.org/10.1073/pnas.1912671116
https://doi.org/10.1073/pnas.1912671116
Autor:
Thomas Wegleiter, Sebastian Jessberger
Publikováno v:
EMBO J
Regulation of adult neural stem cell (NSC) number is critical for lifelong neurogenesis. Here, we identified a post‐transcriptional control mechanism, centered around the microRNA 204 (miR‐204), to control the maintenance of quiescent (q)NSCs. mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2ec75e21d46dd7cf1ba3326623ffe6a
https://pubmed.ncbi.nlm.nih.gov/31304985
https://pubmed.ncbi.nlm.nih.gov/31304985
Autor:
Chiara Rolando, Marta Milo, Verdon Taylor, Anna Engler, Robert Beattie, Sebastian Jessberger, Andrea Erni, Alice Grison, Paul J. Gokhale, Thomas Wegleiter
Publikováno v:
Europe PubMed Central
Adult neural stem cells (NSCs) are defined by their inherent capacity to self-renew and give rise to neurons, astrocytes, and oligodendrocytes. In vivo, however, hippocampal NSCs do not generate oligodendrocytes for reasons that have remained enigmat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1c5363142642fdb34dda2be8a6e3f1b
https://doi.org/10.1016/j.stem.2016.07.003
https://doi.org/10.1016/j.stem.2016.07.003
Autor:
Thomas Wegleiter, Martina Hruzova, Peter Carmeliet, Werner J. Kovacs, Nicola Zamboni, Bart Ghesquière, Darcie L. Moore, Sebastian Jessberger, Gregor-Alexander Pilz, Marlen Knobloch
Publikováno v:
Cell Reports, Vol 20, Iss 9, Pp 2144-2155 (2017)
Cell Reports
Cell Reports, vol. 20, no. 9, pp. 2144-2155
Cell Reports
Cell Reports, vol. 20, no. 9, pp. 2144-2155
Summary Hippocampal neurogenesis is important for certain forms of cognition, and failing neurogenesis has been implicated in neuropsychiatric diseases. The neurogenic capacity of hippocampal neural stem/progenitor cells (NSPCs) depends on a balance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f826a463e691400bc501a1d159a78bb3
https://lirias.kuleuven.be/handle/20.500.12942/686564
https://lirias.kuleuven.be/handle/20.500.12942/686564
Autor:
Pia Aanstad, Tom Stückemann, Olivier Nägele, Günther Böck, Thomas Wegleiter, Katsiaryna Tarbashevich, Erez Raz, Eduard Stefan
Publikováno v:
Development
The Hedgehog (Hh) pathway plays dual roles in proliferation and patterning during embryonic development, but the mechanism(s) that distinguish the mitogenic and patterning activities of Hh signalling are not fully understood. An additional level of c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0581daabc1fb49b8429da5bb88d7be4f
Autor:
Dan E. Gottschling, Yves Barral, Manuel Hotz, Cristina Manatschal, Jackie Vogel, Thomas Wegleiter, Jimmy Ouellet, Daici Chen, Derek L. Lindstrom, Christian Leisner
Publikováno v:
Cell
SummaryLike many asymmetrically dividing cells, budding yeast segregates mitotic spindle poles nonrandomly between mother and daughter cells. During metaphase, the spindle positioning protein Kar9 accumulates asymmetrically, localizing specifically t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50edf840b953c6a46acc597727e93887
https://europepmc.org/articles/PMC3779431/
https://europepmc.org/articles/PMC3779431/
Autor:
Thomas Wegleiter, Hossein Najmabadi, Rupert W. Overall, Megan Bowers, Werner J. Kovacs, Gerd Kempermann, Jochen Winterer, Baptiste N. Jaeger, Tong Liang, Clay F. Semenkovich, Sebastian Jessberger, Sara Zocher, Kaitlyn M.L. Cramb, Clemens Röhrl, Daniel Gonzalez-Bohorquez, Slavica Dimitrieva, Csaba Földy, Merit Kruse
Publikováno v:
Cell stem cell 27(1), 98-109.e11 (2020). doi:10.1016/j.stem.2020.04.002
Summary Altered neural stem/progenitor cell (NSPC) activity and neurodevelopmental defects are linked to intellectual disability. However, it remains unclear whether altered metabolism, a key regulator of NSPC activity, disrupts human neurogenesis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad83535b16c55c7e1d864a8028158c21