Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Thomas Walter Dubensky"'
Autor:
Diwakar Davar, John D. Powderly, Susanna Varkey Ulahannan, Melissa Lynne Johnson, Manish Sharma, John C. Krauss, Robert Stagg, Brian Francica, Anne Moon, Yonchu Jenkins, Peppi Prasit, Thomas Walter Dubensky, Sam H. Whiting, Kyriakos P. Papadopoulos
Publikováno v:
Journal of Clinical Oncology. 40:TPS2696-TPS2696
TPS2696 Background: Prostaglandin E2 (PGE2) is a bioactive lipid that promotes cancer through diverse mechanisms including stimulating tumor proliferation, enhancing angiogenesis and suppressing immune function in the tumor microenvironment. PGE2 pro
Autor:
Mark Yarchoan, John D. Powderly, Bruno R. Bastos, Thomas Benjamin Karasic, Oxana V. Crysler, Pamela N. Munster, Meredith McKean, Leisha A. Emens, Yvonne M. Saenger, Yasser Ged, Robert Stagg, Andreas Goutopoulos, Anne Moon, Yonchu Jenkins, Peppi Prasit, Thomas Walter Dubensky, Sam H. Whiting, Susanna Varkey Ulahannan
Publikováno v:
Journal of Clinical Oncology. 40:3005-3005
3005 Background: TPST-1120 is a first-in-class oral therapy that inhibits PPARα, a transcription factor that regulates fatty acid oxidation (FAO). TPST-1120 has diverse mechanisms of anti-tumor activity in preclinical studies, including inhibiting t