Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Thomas Walle"'
Autor:
Philipp Reimold, Georgi Tosev, Adam Kaczorowski, Jana Friedhoff, Constantin Schwab, Viktoria Schütz, Magdalena Görtz, Niklas Panzer, Martina Heller, Cem Aksoy, Ruth Himmelsbach, Thomas Walle, Stefanie Zschäbitz, Dirk Jäger, Anette Duensing, Albrecht Stenzinger, Markus Hohenfellner, Stefan Duensing
Publikováno v:
Diagnostics, Vol 14, Iss 7, p 741 (2024)
Background: Renal cell carcinoma (RCC) is among the most lethal urologic malignancies once metastatic. Current treatment approaches for metastatic RCC (mRCC) involve immune checkpoint inhibitors (ICIs) that target the PD-L1/PD-1 axis. High PD-L1 expr
Externí odkaz:
https://doaj.org/article/024657d17a2c4da0b88ebf9657dd40fd
Autor:
Dirk Jäger, Hans-Christoph Friederich, Georg Martin Haag, Thomas Walle, Stefanie Zschäbitz, Jürgen Krauß, Imad Maatouk, Christina Sauer, Simeon Sauer, Senta Kiermeier
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Introduction Immune checkpoint therapy (ICT) is associated with a distinct pattern of immune-related adverse events (irAEs) caused by inadvertently redirecting immune responses to healthy tissues. IrAEs can occur at any time; however, in most cases,
Externí odkaz:
https://doaj.org/article/980f2d699e7345a58ec6eee34d411baa
Autor:
Sebastian Schölch, Benedikt Brors, Albrecht Stenzinger, Ursula Ehmer, Ulrich-Frank Pape, Christoph Springfeld, Dirk Jäger, Felix J Hüttner, Andreas Mock, Christoph E Heilig, Simon Kreutzfeldt, Daniel Huebschmann, Christoph Heining, Evelin Schröck, Richard Schlenk, Hanno Glimm, Stefan Fröhling, Peter Horak, Leonidas Apostolidis, Marinela Augustin, Daniela Aust, Irfan Ahmed Bhatti, Johannes Bloehdorn, Cornelia Brendel, Christian Britschgi, Jan Braess, Stefan Burdach, Elena Busch, Jozefina Casuscelli, Alexander Desuki, Thomas Deutsch, Mareike Dietrich, Thomas J Ettrich, Johanna Falkenhorst, Tanja Fehm, Anne Flörcken, Andrea Forschner, Stefan Fuxius, Maria Gonzales-Carmona, Frank Griesinger, Sabine Grill, Stefan Gröschel, Georg Martin Haag, Ulrich Haag, Niels Halama, Holger Hebart, Nina Heidger, Barbara Hermes, Georg Hess, Simone Hettmer, Manuela Hoechstetter, Martin Hoffmann, Anna L Illert, Maximilian Jenzer, Bernd Kasper, Stefan Kasper-Virchow, Thomas Kindler, Ewa Koscielniak, Jan Krönke, Michael Kühn, Volker Kunzmann, Alois Lang, Jonas Leichsenring, Elisabeth Livingstone, Lucia Liotta, Kim Luley, Elisabeth Mack, Uwe M Martens, Klaus Metzeler, Jan Moritz Middeke, Lino Möhrmann, Roopa Jayarama-Naidu, Lukas Perkhofer, Arne Pfeufer, Constantin Pixberg, Michael Quante, Bernhard Rendenbach, Damian Rieke, Christian Rothermundt, Andre Norbert Sagerer, Martin Salzmann, Dieter Saur, Bastian Schilling, Jan Schleicher, Anke Schlenska-Lange, Thomas Schmidt, Sophia Schmitz, Rajiv Shah, Khalid Shoumariyeh, Alexander Siebenhüner, Martin Singh, Jens Siveke, Helen Starke, Sophia Strobel, Veronica Teleanu, Niklas Thon, Sebastian Wagner, Thomas Walle, Benedikt Westphalen, Bettina Whitlock, Eva Winkler, Naita Maren Wirsik, Lena Woydack, Angelika Zabel-du Bois, Stefanie Zschäbitz
Publikováno v:
ESMO Open, Vol 4, Iss 6 (2019)
Objective Measuring the success of molecularly guided therapies is a major challenge in precision oncology trials. A commonly used endpoint is an intra-patient progression-free survival (PFS) ratio, defined as the PFS interval associated with molecul
Externí odkaz:
https://doaj.org/article/0122f1ac148444cbaeb951db5af876a5
Autor:
Thomas Walle, Rafael Martinez Monge, Adelheid Cerwenka, Daniel Ajona, Ignacio Melero, Fernando Lecanda
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 10 (2018)
Radiotherapy (RT) is currently used in more than 50% of cancer patients during the course of their disease in the curative, adjuvant or palliative setting. RT achieves good local control of tumor growth, conferring DNA damage and impacting tumor vasc
Externí odkaz:
https://doaj.org/article/41d96f3dd12b467c8f62dab7d20df538
Publikováno v:
Norsk Museumstidsskrift, Vol 4, Pp 49-49 (2018)
Externí odkaz:
https://doaj.org/article/9688b394873549069c45e976dbbf65b4
Autor:
Thomas Walle
Publikováno v:
International Journal of Molecular Sciences, Vol 10, Iss 11, Pp 5002-5019 (2009)
Dietary flavones have promising chemoprotective properties, in particular with regard to cancer, but problems with low oral bioavailability and sometimes unacceptable toxicity have made their use as protective additives to normal diets questionable.
Externí odkaz:
https://doaj.org/article/f2bde80538fc445ca6c214673fd58f77
Autor:
Ole Vang, Nihal Ahmad, Clifton A Baile, Joseph A Baur, Karen Brown, Anna Csiszar, Dipak K Das, Dominique Delmas, Carmem Gottfried, Hung-Yun Lin, Qing-Yong Ma, Partha Mukhopadhyay, Namasivayam Nalini, John M Pezzuto, Tristan Richard, Yogeshwer Shukla, Young-Joon Surh, Thomas Szekeres, Tomasz Szkudelski, Thomas Walle, Joseph M Wu
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e19881 (2011)
BackgroundResveratrol is a natural compound suggested to have beneficial health effects. However, people are consuming resveratrol for this reason without having the adequate scientific evidence for its effects in humans. Therefore, scientific valid
Externí odkaz:
https://doaj.org/article/304fb5edd52c42c799f803f46c240e79
Autor:
Cassandra Burdziak, Direna Alonso-Curbelo, Thomas Walle, José Reyes, Francisco M. Barriga, Doron Haviv, Yubin Xie, Zhen Zhao, Chujun Julia Zhao, Hsuan-An Chen, Ojasvi Chaudhary, Ignas Masilionis, Zi-Ning Choo, Vianne Gao, Wei Luan, Alexandra Wuest, Yu-Jui Ho, Yuhong Wei, Daniela F. Quail, Richard Koche, Linas Mazutis, Ronan Chaligné, Tal Nawy, Scott W. Lowe, Dana Pe’er
Publikováno v:
Science. 380
The response to tumor-initiating inflammatory and genetic insults can vary among morphologically indistinguishable cells, suggesting as yet uncharacterized roles for epigenetic plasticity during early neoplasia. To investigate the origins and impact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c1d23407cd338152d43ece94589b91a
https://doi.org/10.1126/science.add5327
https://doi.org/10.1126/science.add5327
Autor:
Rafael Martínez-Monge, Fernando Lecanda, Ignacio Melero, Silvestre Vicent, Carlos E. de Andrea, María E. Rodríguez-Ruiz, Rubén Pío, Sandra Hervás-Stubbs, Dominique Heymann, Vratislav Strnad, Laura Guembe, Luis I. Ramos-García, Marta Santisteban, Carlos Ortiz de Solórzano, Xabier Morales, Sergio Ortiz-Espinosa, Daniel Ajona, Álvaro Teijeira, Susana Martínez-Canarias, Carolina Zandueta, Denis Cochonneau, Marta Abengózar-Muela, Antonio Pineda-Lucena, Elisabet Guruceaga, Juan Hinojosa, Alberto Pezonaga-Torres, Thomas Walle, Pablo Ruedas, Naiara Perurena, Karmele Valencia, Haritz Moreno, Borja Ruiz-Fernández de Córdoba
Locoregional failure (LRF) in patients with breast cancer post-surgery and post-irradiation is linked to a dismal prognosis. In a refined new model, we identified ectonucleotide pyrophosphatase/phosphodiesterase 1/CD203a (ENPP1) to be closely associa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f26387c97cae4c74421dd25469470ce
https://doi.org/10.1158/2159-8290.c.6549629.v1
https://doi.org/10.1158/2159-8290.c.6549629.v1
Autor:
Rafael Martínez-Monge, Fernando Lecanda, Ignacio Melero, Silvestre Vicent, Carlos E. de Andrea, María E. Rodríguez-Ruiz, Rubén Pío, Sandra Hervás-Stubbs, Dominique Heymann, Vratislav Strnad, Laura Guembe, Luis I. Ramos-García, Marta Santisteban, Carlos Ortiz de Solórzano, Xabier Morales, Sergio Ortiz-Espinosa, Daniel Ajona, Álvaro Teijeira, Susana Martínez-Canarias, Carolina Zandueta, Denis Cochonneau, Marta Abengózar-Muela, Antonio Pineda-Lucena, Elisabet Guruceaga, Juan Hinojosa, Alberto Pezonaga-Torres, Thomas Walle, Pablo Ruedas, Naiara Perurena, Karmele Valencia, Haritz Moreno, Borja Ruiz-Fernández de Córdoba
Supplementary Figure from Tumor ENPP1 (CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b0e1b670481e8b65017fa49e8e3a330
https://doi.org/10.1158/2159-8290.22541390.v1
https://doi.org/10.1158/2159-8290.22541390.v1