Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thomas Walko"'
Autor:
Nicholas J Izzo, Agnes Staniszewski, Lillian To, Mauro Fa, Andrew F Teich, Faisal Saeed, Harrison Wostein, Thomas Walko, Anisha Vaswani, Meghan Wardius, Zanobia Syed, Jessica Ravenscroft, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Patricia Finn, Gary Look, Gilbert Rishton, Hank Safferstein, Miles Miller, Conrad Johanson, Edward Stopa, Manfred Windisch, Birgit Hutter-Paier, Mehrdad Shamloo, Ottavio Arancio, Harry LeVine, Susan M Catalano
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e111898 (2014)
Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic beta amyloid (Abeta) 1-42 oligomers is proposed to underlie cognitive decline in Alzheimer's disease (AD). Alterations in membrane trafficking induced by Abeta oligome
Externí odkaz:
https://doaj.org/article/7588522c8af84352a18c72ff5aa5c7b2
Autor:
Lisa Pan, Lora McClain, Thomas Walko, Rebecca B. Price, Manivel Rengasamy, Tessa Kovats, Anna L. Marsland
Publikováno v:
Brain Behav Immun
Background Depression has been associated with low-grade elevation of plasma cytokines (e.g. interleukin-6, IL-6; tumor necrosis factor alpha, TNFα) in both cross-sectional and longitudinal studies in adults. Preclinical and clinical studies also su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89ee0e91bc9de07dd69032ba07ba95cf
https://pubmed.ncbi.nlm.nih.gov/32919038
https://pubmed.ncbi.nlm.nih.gov/32919038
Autor:
Thomas Walko, Lora McClain, Tessa Kovats, Lisa Pan, Manivel Rengasamy, Anna L. Marsland, Rebecca B. Price
Publikováno v:
Psychoneuroendocrinology
Background Evidence supports raised circulating levels of inflammatory mediators, such as interleukin-6 (IL-6) and tumor necrosis factor (TNFα), among clinically depressed adults, although preliminary findings in adolescents are mixed. Independently
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb715f43a07eb6dd8e859bfcb05a1b24
https://doi.org/10.1016/j.psyneuen.2021.105398
https://doi.org/10.1016/j.psyneuen.2021.105398
Autor:
Diana Pang, Victor Hsue, Thomas Walko, Yijen L. Wu, Jessica Cummings, Alicia M. Alcamo, Valentina Di Caro, Patrick M. Kochanek, Robert S. B. Clark, Rajesh K. Aneja, Ashok Panigrahy
Publikováno v:
Shock
Sepsis-induced brain injury is associated with an acute deterioration of mental status resulting in cognitive impairment and acquisition of new functional limitations in sepsis survivors. However, the exact nature of brain injury in this setting is o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6003b5895a629d02f3c831760df773d
https://pubmed.ncbi.nlm.nih.gov/31513049
https://pubmed.ncbi.nlm.nih.gov/31513049
Autor:
Valentina Di Caro, John D. Hong, Victor Hsue, Robert S. B. Clark, Diana Pang, Rajesh K. Aneja, R. Aaron Bola, Joseph A. Carcillo, E. Scott Halstead, Thomas Walko, Alicia K. Au
Publikováno v:
Shock. 45:506-511
Mitochondrial DNA (mtDNA) is a novel danger-associated molecular pattern that on its release into the extracellular milieu acts via toll-like receptor-9, a pattern recognition receptor of the immune system. We hypothesized that plasma mtDNA concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7844d981e553764837b9a8c7cabb1dd6
https://doi.org/10.1097/shk.0000000000000539
https://doi.org/10.1097/shk.0000000000000539
Autor:
Alicia M. Alcamo, Raj Aneja, Thomas Walko, Valentina Di Caro, Yijen L. Wu, Jessica Cummings, Ashok Panigrahy, Victor Hsue, Robert B. Clark, Diana Pang, Patrick M. Kochanek
Publikováno v:
Critical Care Medicine. 48:820-820
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e9e6ec5a2af298884d63bc00326ca18
https://doi.org/10.1097/01.ccm.0000648664.77079.5b
https://doi.org/10.1097/01.ccm.0000648664.77079.5b
Autor:
Rajesh K. Aneja, Patrick M. Kochanek, Michael J. Bell, Thomas Walko, Alicia K. Au, R. Aaron Bola, John D. Hong, Robert S. B. Clark
Publikováno v:
Shock. 41:499-503
Danger-associated molecular patterns (DAMPs) are nuclear or cytoplasmic proteins that are released from the injured tissues and activate the innate immune system. Mitochondrial DNA (mtDNA) is a novel DAMP that is released into the extracellular milie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92a4aac0c8707cedc3d65c16a21c2736
https://doi.org/10.1097/shk.0000000000000160
https://doi.org/10.1097/shk.0000000000000160
Autor:
Rajesh K. Aneja, Jon D. Piganelli, Valentina Di Caro, Timothy R. Billiar, Robert S. B. Clark, Thomas Walko
Pathophysiological conditions that lead to the release of the prototypic damage-associated molecular pattern molecule high mobility group box 1 (HMGB1) also result in activation of poly(ADP-ribose) polymerase 1 (PARP1; now known as ADP-ribosyl transf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc04ebc221e40c5b497cf4bc4fb6461a
https://europepmc.org/articles/PMC4365057/
https://europepmc.org/articles/PMC4365057/
Autor:
Miles C. Miller, Zanobia Syed, Agnes Staniszewski, Kelsie Mozzoni, Manfred Windisch, Thomas Walko, Patricia W. Finn, Edward G. Stopa, Nicholas J. Izzo, Andrew F. Teich, Mauro Fa, Anisha Vaswani, Faisal Saeed, Hank Safferstein, Ottavio Arancio, Meghan Wardius, Birgit Hutter-Paier, Gilbert M. Rishton, Courtney Rehak, Raymond Yurko, Colleen Silky, Mehrdad Shamloo, Jessica Ravenscroft, Conrad E. Johanson, Gary C. Look, Lillian K. To, Harry LeVine, Susan M. Catalano, Harrison S. Wostein
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e111898 (2014)
PLoS ONE, Vol 9, Iss 11, p e111898 (2014)
Synaptic dysfunction and loss caused by age-dependent accumulation of synaptotoxic beta amyloid (Abeta) 1–42 oligomers is proposed to underlie cognitive decline in Alzheimer's disease (AD). Alterations in membrane trafficking induced by Abeta oligo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ee51f4326a4b0c64e37d33e29323eb7
https://pubmed.ncbi.nlm.nih.gov/25390368
https://pubmed.ncbi.nlm.nih.gov/25390368
Autor:
Patrick M. Kochanek, Ronald Aaron Bola, Alicia Au, Michael J. Bell, Thomas Walko, Robert B. Clark, Raj Aneja
Publikováno v:
Critical Care Medicine. 41:A4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8074361ca385ad856485d010bccff998
https://doi.org/10.1097/01.ccm.0000439200.84834.22
https://doi.org/10.1097/01.ccm.0000439200.84834.22