Výsledky vyhledávání - "Thomas Wai-hung Lo"

Rational design, engineer, and characterization of a novel pegylated single isomer human arginase for arginine depriving anti-cancer treatment

Autor: Sai Fung Chung, Murray Cutler, Lynn Y L Huang, Thomas Wai-hung Lo, Johnson Y.N. Lau, Kuo-Ming Yu, Tammy Pui-shi Pang, Thomas Yun-Chung Leung, Min Tian

Publikováno v: Life Sciences. 264:118674

Aims Arginine depleting enzymes are found effective to treat arginine-auxotrophic cancers and therapy-resistant malignancies, alone or in combination with cytotoxic agents or immune checkpoint inhibitors. We aim to select and validate a long-lasting,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15a559b1f4076b002392d9d74a929bf0
https://doi.org/10.1016/j.lfs.2020.118674

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Design, engineering, and characterization of a novel long-acting (Pegylated) single isomer human arginase for arginine depriving anticancer treatment

Autor: Thomas Yun-Chung Leung, Kuo-Ming Yu, Murray Cutler, Johnson Y.N. Lau, Thomas Wai-hung Lo, Tammy Pui-shi Pang

Publikováno v: Journal of Clinical Oncology. 37:3090-3090

3090 Background: Arginine deprivation therapy is an attractive strategy to treat arginine-auxotrophic cancers with deficient expression of argininosuccinate synthetase, argininosuccinate lyase or ornithine transcarbamylase. We have designed and engin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48b37a929df00a074ae5252ffe7bff92
https://doi.org/10.1200/jco.2019.37.15_suppl.3090

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Removal of residual pesticides on vegetable using ozonated water

Autor: Chongyu Lan, Gilbert Y.S. Chan, Thomas Wai-hung Lo, Tiangang Luan, Jiguo Wu

Publikováno v: Food Control. 18:466-472

Degradation of the four pesticides by dissolved ozone was investigated in order to establish the effect of operational parameters: methyl-parathion, parathion, diazinon and cypermethrin. They were commonly used as broad-spectrum insecticides in pest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a813fbfaf0f234db0bf3dd02fc3bc30
https://doi.org/10.1016/j.foodcont.2005.12.011

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Highly enantioselective hydrogenation of enamides catalyzed by rhodium-monodentate phosphoramidite complex derived from H8-BINOL

Autor: Gui Lu, Xingshu Li, Terry T.‐L. Au‐Yeung, Albert S. C. Chan, Xian Jia, Kim Hung Lam, Thomas Wai-hung Lo

Publikováno v: Tetrahedron: Asymmetry. 14:2687-2691

A series of monodentate phosphoramidite ligands derived from H 8 -BINOL have been synthesized. The ligands are used in the Rh-catalyzed asymmetric hydrogenation of enamides to give the acetamides in up to 99% ee.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4e9095d88f0fc666fcc2fbe22a11af
https://doi.org/10.1016/j.tetasy.2003.07.005

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