Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Thomas W. Strickland"'
Publikováno v:
Luteinizing Hormone Action and Receptors ISBN: 9780429285684
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc7f58210abbf598295f42898c4c3417
https://doi.org/10.1201/9780429285684-1
https://doi.org/10.1201/9780429285684-1
Publikováno v:
International Journal of Peptide and Protein Research. 47:201-208
Recombinant human erythropoietin (rHuEPO) is biologically functional when in a monomeric state; upon extensive heating, rHuEPO forms a dimer. The nature of this dimeric linkage was investigated after isolation of the dimer by gel filtration. The dime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ffb1fdeb32994b204c8304398278f5
https://doi.org/10.1111/j.1399-3011.1996.tb01345.x
https://doi.org/10.1111/j.1399-3011.1996.tb01345.x
Publikováno v:
International Journal of Peptide and Protein Research. 24:328-336
The susceptibility of the tyrosines of bovine thyrotropin (bTSH) and of its isolated alpha and beta subunits to lactoperoxidase catalyzed iodination was examined as a probe of the reactivity of these residues. In isolated TSH alpha, tyrosines at posi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78d9701138b5cdff8be2cbad32ad02bb
https://doi.org/10.1111/j.1399-3011.1984.tb00960.x
https://doi.org/10.1111/j.1399-3011.1984.tb00960.x
Autor:
Thomas W. Strickland, Seiichi Takasaki, Tadashi Misaizu, Makoto Takeuchi, Shigeru Matsuki, Akira Kobata
Publikováno v:
Blood. 86:4097-4104
To elucidate the role of the branched structure of sugar chains of human erythropoietin (EPO) in the expression of in vivo activity, the pharmacokinetic profile of a less active recombinant human EPO sample (EPO-bi) enriched with biantennary sugar ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66048f6477570ee8a4d2081f0a7989f
https://doi.org/10.1182/blood.v86.11.4097.bloodjournal86114097
https://doi.org/10.1182/blood.v86.11.4097.bloodjournal86114097
Publikováno v:
Analytical Chemistry. 65:1834-1842
High-performance capillary electrophoresis (HPCE) has been employed to characterize the peptide map of recombinant human erythropoietin (rHuEPO) expressed from Chinese hamster ovary (CHO) cells. The methodology employs an ion pairing agent, 100 mM he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7873dfdb56b61510101c67f69149251d
https://doi.org/10.1021/ac00062a007
https://doi.org/10.1021/ac00062a007
Autor:
Thomas W. Strickland, Linda O. Narhi, Michael F. Rohde, Tsutomu Arakawa, Tom Boone, Kenneth H. Aoki, R Elmore
Publikováno v:
Journal of Biological Chemistry. 266:23022-23026
Erythropoietin is a glycoprotein hormone that stimulates the maturation of late erythroid progenitor cells. It has three N-linked and one O-linked carbohydrates which play an important role in the biosynthesis and biological activities of the protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d6a4fbde81e71b7e0ed1cfbd3a1d93f
https://doi.org/10.1016/s0021-9258(18)54457-4
https://doi.org/10.1016/s0021-9258(18)54457-4
Publikováno v:
Journal of Biochemical and Biophysical Methods. 23:295-300
Carbohydrates play important roles in activity, stability and pharmacokinetics of glycoproteins and the degree of glycosylation varies with proteins. In this communication, a simple method of determining the carbohydrate content was developed, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3fff92ea9d44dfaa76e7d4ae4f54b89
https://doi.org/10.1016/0165-022x(91)90004-g
https://doi.org/10.1016/0165-022x(91)90004-g
Autor:
Jette Wypych, Dennis Fenton, Thomas W. Strickland, Keith Langley, Thor F. Berg, Thomas C. Boone
Publikováno v:
European Journal of Biochemistry. 163:313-321
The isolation of bacterially synthesized, recombinant-DNA-derived, bovine growth hormone (r-bGH) with native structure is described. The r-bGH is found in insoluble form, in a pellet fraction, after cell breakage and centrifugation. Cell envelope com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46c696a43feaa3ab2f4ed3993b8439a
https://doi.org/10.1111/j.1432-1033.1987.tb10802.x
https://doi.org/10.1111/j.1432-1033.1987.tb10802.x
Autor:
Thomas W. Strickland, David Puett
Publikováno v:
Endocrinology. 109:1933-1942
The alpha- and beta-subunits of hCG and of ovine and porcine LH were used to prepare all nine homologous and heterologous alpha beta-recombinants. EAch purified recombinant was assayed in vitro, using dispersed Leydig tumor cells derived from the M54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bca3586a50277ef313dbad12ff8c69a
https://doi.org/10.1210/endo-109-6-1933
https://doi.org/10.1210/endo-109-6-1933
Publikováno v:
Endocrinology. 116:2122-2124
TSH binds specifically to the TSH receptor present on the surface of thyroid follicular cells and consequently activates adenylate cyclase. It was not known, however, which of the two subunits of the TSH bound to the receptor. By covalently crosslink
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f3e188386408cd38b436ae020da65a0
https://doi.org/10.1210/endo-116-5-2122
https://doi.org/10.1210/endo-116-5-2122