Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Thomas W. Stief"'
Autor:
Thomas W. Stief
Publikováno v:
Drug Target Insights, Vol 2, Pp 83-96 (2007)
Background: Phospholipases A2 (PLA2) are aggressive enzymes that can destroy phospholipids of cell membranes. The resulting cell fragments trigger the kallikrein—mediated contact phase of coagulation. The aim of the present study was to expose citr
Externí odkaz:
https://doaj.org/article/c4bd86ec132848a29c8fb5d8dae338df
Autor:
Thomas W. Stief
Publikováno v:
Drug Target Insights, Vol 1, Pp 6-11 (2006)
Background: The contact phase of coagulation is of physiologic/pathophysiologic importance, whenever unphysiologic polynegative substances such as cell fragments (microparticles) get in contact with blood. There are several clinically used inhibitors
Externí odkaz:
https://doaj.org/article/b5323c27652348f8bd1f7827df176d6d
Autor:
Thomas W. Stief
Publikováno v:
Drug Target Insights, Vol 2, Iss 1 (2007)
Abstract non disponibile
Externí odkaz:
https://doaj.org/article/f2cbdbd8768546a3819fd3025e91e383
Autor:
Thomas W. Stief
Publikováno v:
Drug Target Insights, Vol 1, Iss 1 (2006)
Abstract non disponibile
Externí odkaz:
https://doaj.org/article/fd055fcb4a894ce4a3361e343c6e6c14
Autor:
Stefan Strodthoff, Stefan Mennel, Michael Janusz Koss, Nauke Nguyen, Walter Sekundo, Thomas W. Stief, M. Witteborn, Thomas Bertelmann
Publikováno v:
Der Ophthalmologe. 112:155-161
Ziel der vorliegenden Studie war es, verschiedene intravitreale Fibrinolyseparameter zu analysieren und zwischen Augen mit retinalem Zentralvenenverschluss (ZVV), retinalem Venenastverschluss (VAV) und einer Kontrollgruppe zu vergleichen. Die gefunde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9e5cec1419be0b16d913b44a47dab45
https://doi.org/10.1007/s00347-014-3107-z
https://doi.org/10.1007/s00347-014-3107-z
Autor:
Thomas W. Stief
Publikováno v:
Journal of Diabetes Mellitus. :15-21
Background: Glucose is the main substrate for the generation of NADPH, the cofactor of the oxidative burst enzyme NADPH-oxidase of blood neutrophils. Changes in blood glucose are thus expected to modify the generation of reactive oxygen species (ROS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ae62b4d6029e0b039968765061daad
https://doi.org/10.4236/jdm.2013.31003
https://doi.org/10.4236/jdm.2013.31003
Autor:
Michael Janusz Koss, Stefan Mennel, Thomas Bertelmann, Michael C P Witteborn, Thomas W. Stief, Walter Sekundo, Nauke Nguyen, Stefan Strodthoff
Publikováno v:
Ophthalmic Research. 50:151-159
Purpose: To detect intravitreal functional plasminogen in vitreous samples of patients with recent onset of central retinal vein occlusion (CRVO) and to demonstrate significantly higher intravitreal plasminogen in CRVO patients in comparison to contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7014cde1b895908ab5e3ca4e2cd6d99a
https://doi.org/10.1159/000351632
https://doi.org/10.1159/000351632
Publikováno v:
Journal of Diabetes Mellitus. :47-51
Background: Systemic thrombin activity (F2a), i.e. thrombin protected and transported by a2- macroglobulin, is a new biomarker for the activation state of coagulation in vivo. F2a > 120% of normal diagnoses a pathologic disseminated intravascular coa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b41655f7369cca3121e75e959df90ce
https://doi.org/10.4236/jdm.2012.21008
https://doi.org/10.4236/jdm.2012.21008
Publikováno v:
Experimental Eye Research. 121:23-25
The purpose of this research project was to evaluate if intravitreal opsins are present in human vitreous liquid which is, so far, unknown. Therefore a pilot study was conducted including 22 vitreal samples which were harvested at the beginning of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a60cec0dc58b95d60bab84a65960848
https://doi.org/10.1016/j.exer.2014.02.012
https://doi.org/10.1016/j.exer.2014.02.012
Publikováno v:
Blood Coagulation & Fibrinolysis. 25:94-96
An intact blood-retina barrier (BRB) ensures the homeostatic regulation of the retinal environment by preventing proteins and enzymes to pass from the blood stream into the retinal tissue as well as the vitreous cavity ('nonleaky eyes'). Nevertheless
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46413cae13e7633d934aa22dee332d16
https://doi.org/10.1097/mbc.0b013e328364c266
https://doi.org/10.1097/mbc.0b013e328364c266