Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Thomas W. Seale"'
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136867 (2015)
Nontypeable Haemophilus influenzae (NTHi) cause significant disease, including otitis media in children, exacerbations of chronic obstructive pulmonary disease, and invasive disease in susceptible populations. No vaccine is currently available to pre
Externí odkaz:
https://doaj.org/article/9a2cdcd40adc49518730357c039c76ec
Autor:
Paul W Whitby, Daniel J Morton, Timothy M Vanwagoner, Thomas W Seale, Brett K Cole, Huda J Mussa, Phillip A McGhee, Chee Yoon S Bauer, Jennifer M Springer, Terrence L Stull
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50588 (2012)
To prevent damage by reactive oxygen species, many bacteria have evolved rapid detection and response systems, including the OxyR regulon. The OxyR system detects reactive oxygen and coordinates the expression of numerous defensive antioxidants. In m
Externí odkaz:
https://doaj.org/article/fc110bf57e3045809b02dceec5e39e3e
Publikováno v:
Hearing Research. 350:22-31
Acute otitis media (AOM) is a rapid-onset infection of the middle ear which results in middle ear pressure (MEP), middle ear effusion (MEE), and structural changes in middle ear tissues. Previous studies from our laboratory have identified that MEP,
Publikováno v:
International Journal of Pediatric Otorhinolaryngology. 88:74-81
Objective The round window membrane (RWM) encloses the round window, the opening into the scala tympani (ST) from the middle ear. During the course of acute otitis media (AOM), structural changes of the RWM can occur that potentially affect sound tra
Publikováno v:
Hearing research. 370
Mechanical properties of the tympanic membrane (TM) are important for studying the transfer function of the auditory system. However, nearly all reported human data are limited to adults because of the unavailability of temporal bones from children.
Publikováno v:
International Journal of Pediatric Otorhinolaryngology. 79:1462-1471
The tympanic membrane (TM) couples sound waves entering the outer ear canal to mechanical vibrations of the ossicular chain in the middle ear. During acute otitis media (AOM), dynamic structural changes in the TM can occur, which potentially affect s
Autor:
Lauren O. Bakaletz, Daniel J. Morton, Terrence L. Stull, Thomas W. Seale, Timothy M. VanWagoner, Ann Smith, Paul W. Whitby, Joseph A. Jurcisek
Publikováno v:
International Journal of Medical Microbiology. 299:479-488
Haemophilus influenzae has an absolute growth requirement for heme and the heme-binding lipoprotein (HbpA) and has been implicated in the utilization of this essential nutrient. We constructed an insertional mutation of hbpA in a type b and a nontype
Publikováno v:
FEMS Microbiology Letters. 279:157-161
Haemophilus influenzae requires two growth factors, designated factor X (porphyrin) and factor V (NAD). Mammalian catalases contain both bound heme and NADPH. This study shows that catalase can supply both factors X and V to H. influenzae in vitro, t
Autor:
Larissa L. Madore, Timothy M. VanWagoner, Terrence L. Stull, Daniel J. Morton, Paul W. Whitby, Thomas W. Seale
Publikováno v:
Microbiology. 153:215-224
Haemophilus influenzae has an absolute growth requirement for a porphyrin source, which can be supplied in vitro by haem, haemoglobin, or the haemoglobin-haptoglobin, haem-haemopexin and haem-albumin complexes. Utilization of the haem-haemopexin comp
Autor:
Daniel J. Morton, Terrence L. Stull, Timothy M. VanWagoner, Thomas W. Seale, Huda J. Mussa, Paul W. Whitby
Publikováno v:
Genome Announcements
Nontypeable Haemophilus influenzae is an important cause of human disease. Strains were selected for genome sequencing to represent the breadth of nontypeable strains within the species, as previously defined by the electrophoretic mobility of 16 met