Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Thomas W. Menard"'
Autor:
Virginia K. Anderson, Thomas W. Menard, Lynn S. Mandel, Doris J. Stiefel, Edmond L. Truelove, Patricia E. Doyle
Publikováno v:
Special Care in Dentistry. 10:6-12
Severe dental disease has been reported for patients receiving psychiatric treatment. This study compared the oral status of noninstitutionalized adults with chronic mental illness with a similar group without such history, and evaluated relative ris
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1794557090198b85896bc2ad595e3c83
https://doi.org/10.1111/j.1754-4505.1990.tb01079.x
https://doi.org/10.1111/j.1754-4505.1990.tb01079.x
Autor:
Alexander M. Spence, Thomas B. Osgood, John I. Clark, Jeannette E. Steele, Kenneth A. Krohn, John C. Livesey, Thomas W. Menard
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 12:1483-1486
Protection by WR-77913 against radiation-induced cataract formation in rats was observed following intraperitoneal (i.p.) administration of drug (1160 mg/kg) 15-30 min before exposure to 15.3 Gy of Cs-137 whole head irradiation. Control groups includ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27a856c8e9705b0a91ece5e2bd0973d9
https://doi.org/10.1016/0360-3016(86)90199-9
https://doi.org/10.1016/0360-3016(86)90199-9
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 12:1487-1490
The organ level biodistribution and tumor radioprotective properties of three drugs have been compared: WR-2721 (NSC 296961), WR-3689 (NSC 327729), and WR-77913 (NSC 318809). The three drugs have similar distribution patterns in normal mouse tissues.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5dec0058868def89c3b2ac34adfc79a
https://doi.org/10.1016/0360-3016(86)90200-2
https://doi.org/10.1016/0360-3016(86)90200-2
Autor:
Ingegerd Hellström, Paul L. Beaumier, Karl Erik Hellström, Raj Kishore, Kenneth A. Krohn, Janet F. Eary, Thomas W. Menard, Wil B. Nelp
Publikováno v:
International Journal of Radiation Applications and Instrumentation. Part B. Nuclear Medicine and Biology. 13:457-459
We investigated the effects of ionizing radiation on the immunointegrity of antibody fragments (Fab) because large amounts of high specific activity 131 I may damage the proteins. We found that 1000 Gy of external 137 Cs γ radiation was sufficient t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5086c3d721cfc5a88e616c043bf94548
https://doi.org/10.1016/0883-2897(86)90025-5
https://doi.org/10.1016/0883-2897(86)90025-5
Autor:
Kenneth A. Krohn, Roger B. Phillips, Zdenka Grunbaum, Janet S. Rasey, Thomas W. Menard, Peter A. Mahler, Kent W. Anderson, Alexander M. Spence
Publikováno v:
International journal of radiation oncology, biology, physics. 10(9)
Studies with WR-2721 and related compounds have been hindered by the lack of a suitable assay for the drug and its major metabolites. We have developed a chromatographic method which requires no derivatization for the separation and detection of WR-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c4027a4728107d46f8cb238e257777d
https://pubmed.ncbi.nlm.nih.gov/6090353
https://pubmed.ncbi.nlm.nih.gov/6090353
Autor:
Thomas W. Menard, W.Y. Ensign, Patricia J. Keller, Kenneth T. Izutsu, Thomas H. Morton, Edmond L. Truelove
Publikováno v:
International journal of radiation oncology, biology, physics. 10(9)
Changes in rat parotid salivary gland weight and functional parameters were evaluated at 8 to 10 days post irradiation in V1'R-2721 protected and non-protected animals following exposure to a single 15.3 Gy dose of Cs-137 radiation to the head. Gland
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4d3c0bbab8105eed333e7bbab7ffc6b
https://pubmed.ncbi.nlm.nih.gov/6090361
https://pubmed.ncbi.nlm.nih.gov/6090361
Publikováno v:
Radiation Research. 102:130
3-Amino-2-hydroxypropyl phosphorothioate (WR77913), a less toxic phosphorothioate radioprotector than WR2721, has been labeled with 35S. The biodistribution of a radioprotective dose of 800 mg/kg was determined in C3H mice bearing RIF-1 tumors as a f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b67dc4eeff3f3b4ef12d7e97a6dd8a1f
https://doi.org/10.2307/3576436
https://doi.org/10.2307/3576436
Autor:
Kenneth A. Krohn, Norma J. Nelson, Janet S. Rasey, Thomas W. Menard, Peter A. Mahler, Kent W. Anderson
Publikováno v:
Radiation Research. 97:598
The ability of WR-2721 to protect mice against two modes of death following whole-body radiation with 137Cs gamma rays or d(22)+Be neutrons was examined. For single fractions, 400 mg/kg WR-2721 was administered prior to irradiation. In two-fraction e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::678912ce8e81e99c0fc9dc37298b28fd
https://doi.org/10.2307/3576151
https://doi.org/10.2307/3576151
Autor:
Robert A. Wade, Thomas W. Menard, Kenneth A. Krohn, Alexander M. Spence, Janet S. Rasey, Zdenka Grunbaum
Publikováno v:
Radiation Research. 106:366
35S- and 3H-labeled S-2-(3-methylaminopropylamino)ethylphosphorothioic acid (WR-3689) have been synthesized in our laboratory and used to study organ and cellular level distribution in C3H/Km mice bearing RIF-1 tumors. Tissue biodistributions obtaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82c9f0d56a684644f97d4ba9ca2a917f
https://doi.org/10.2307/3576744
https://doi.org/10.2307/3576744
Autor:
James C. Rice, Thomas H. Morton, Marc W. Anderson, Ivens A. Siegel, Thomas W. Menard, Edmond L. Truelove, Kenneth T. Izutsu
Publikováno v:
Radiation Research. 90:330
Changes in rat parotid gland function were measured between 3 and 30 days following exposure to 1800 R of137 Cs irradiation to the head. Glandular fluid secretion capability as indicated by volume of secretion, maximum rate of secretion, and duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f95f26371154c176b9d63b64d1dc74f
https://doi.org/10.2307/3575710
https://doi.org/10.2307/3575710