Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Thomas W. Dunlop"'
Autor:
Otto T Mykkänen, Anne Huotari, Karl-Heinz Herzig, Thomas W Dunlop, Hannu Mykkänen, Pirkka V Kirjavainen
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e114790 (2014)
BackgroundLow-grade metabolic inflammation and hypertension are primary mechanisms involved in obesity-associated adverse health effects. Berries, especially Nordic wild blueberries (hereafter referred to as bilberries), represent an important source
Externí odkaz:
https://doaj.org/article/fc671af4e9f34845b4cb9b0d35bdf40d
Autor:
Genevieve Bart, Thomas W. Dunlop, Markku Tammi, Petri Pehkonen, P. Salonen, Sanna Pasonen-Seppänen, Timo Kumlin, Raija Tammi, M. Kokkonen, Leena Rauhala, L. Hämäläinen
Publikováno v:
British Journal of Dermatology. 171:376-387
Summary Background Excessive skin exposure to solar radiation damages proteins and DNA, ultimately leading to skin ageing and cancers. Objectives To identify new ultraviolet B (UVB) target genes to understand the mechanisms behind the detrimental eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8e7e2657c476ce80edaec9a96753188
https://doi.org/10.1111/bjd.13038
https://doi.org/10.1111/bjd.13038
Autor:
Lisa Wiesmüller, Hellevi Peltoketo, Thomas W. Dunlop, Jonas Willmann, Ganapathy Raman Devarajan, Lisa Heiserich, Hanna Tuppurainen, Robert Winqvist, Katri Pylkas, Pentti Nieminen, Kerstin Borgmann, Niina Laurila, Marco Groth, Felix Meyer, Muthiah Bose, Leila Eshraghi, Katrin Rapakko, Thomas Wolfram Paul Friedl, Juliane Sachsenweger, Helmut Pospiech, Ann Christin Parplys, Heli Nevanlinna
Publikováno v:
Cancer Research. 78:339-339
Whilst heterozygous germline mutations in the ABRAXAS gene have been associated with hereditary breast cancer predisposition, their initial effect on promoting tumorigenesis at the cellular level has not been explored. Here, we demonstrate in patient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77c04509a8d8485be81cc5b0b858ac98
https://doi.org/10.1158/1538-7445.am2018-339
https://doi.org/10.1158/1538-7445.am2018-339
Publikováno v:
Nucleic Acids Research
The human 25-hydroxyvitamin D3 (25(OH)D3) 1alpha-hydroxylase, which is encoded by the CYP27B1 gene, catalyzes the metabolic activation of the 25(OH)D3 into 1alpha,25-dihydroxyvitamin D3 (1alpha,25(OH)2D3), the most biologically potent vitamin D3 meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40642010e16e601bc4662f39dc78336c
https://doi.org/10.1093/nar/gkm179
https://doi.org/10.1093/nar/gkm179
Autor:
Lasse Sinkkonen, Carsten Carlberg, Thomas W. Dunlop, Merja Matilainen, Sami Väisänen, Anna Saramäki
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 103:338-343
An essential prerequisite for the direct modulation of transcription by 1α,25-dihydroxy vitamin D 3 (1α,25(OH) 2 D 3 ) is the location of at least one activated vitamin D receptor (VDR) protein close to the transcription start site of the respectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15cbfc405707cb243757e9b19a1d1931
https://doi.org/10.1016/j.jsbmb.2006.12.044
https://doi.org/10.1016/j.jsbmb.2006.12.044
Autor:
Markku Tammi, Thomas W. Dunlop, Leena Rauhala, L. Hämäläinen, Petri Pehkonen, Raija Tammi, Sanna Pasonen-Seppänen, Maarit Kokkonen, Genevieve Bart
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 30(1 Pt)
The moisturizing and potentially protective properties of the organic osmolyte betaine (trimethylglycine) have made it an attractive component for skin care products. Its wide use despite the lack of comprehensive studies addressing its specific effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3982fc33270a2c324a836ecde0c575cd
https://pubmed.ncbi.nlm.nih.gov/26391144
https://pubmed.ncbi.nlm.nih.gov/26391144
Publikováno v:
Journal of Biological Chemistry. 281:39607-39619
Insulin-like growth factor-binding protein 1 (IGFBP-1) is a biomarker for metabolic and hyperproliferative diseases. At the same time, the nuclear receptors peroxisome proliferator-activated receptors (PPARs) are known for their critical role in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::900688c36c01daf1320643fb9bbf3c05
https://doi.org/10.1074/jbc.m605623200
https://doi.org/10.1074/jbc.m605623200
Autor:
Thomas W. Dunlop, Sami Väisänen, Ferdinand Molnár, Lasse Sinkkonen, Christian Frank, Carsten Carlberg
Publikováno v:
Journal of Molecular Biology. 349:248-260
Peroxisome proliferator-activated receptor (PPAR) delta is the most widely expressed member of the PPAR family of nuclear receptor fatty acid sensors. Real-time PCR analysis of breast and prostate cancer cell lines demonstrated that PPARdelta express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b8d2e78c19d5351f07b4653d19cd68
https://doi.org/10.1016/j.jmb.2005.03.060
https://doi.org/10.1016/j.jmb.2005.03.060
Autor:
Christina A. Reeb, Sami Väisänen, Aria Baniahmad, Udo Moehren, Thomas W. Dunlop, Uwe Dressel, Carsten Carlberg
Publikováno v:
Nucleic Acids Research. 32:2995-3004
The Sin3 proteins are evolutionarily conserved co-repressors (CoR) that function as mediators of gene repression for a variety of transcriptional silencers. The paired amphipathic helices of Sin3A were identified and studied as protein–protein inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bc7d4ce4350a41ec334d8fee216f919
https://doi.org/10.1093/nar/gkh621
https://doi.org/10.1093/nar/gkh621
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. :257-260
The complex of the receptor for the hormone 1alpha,25-dihydroxyvitamin D(3) (1alpha,25(OH)(2)D(3)), Vitamin D(3) receptor (VDR), the retinoid X receptor (RXR) and a 1alpha,25(OH)(2)D(3) response element (VDRE) is considered to be the molecular switch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::359a1e850c70c77bd6a03053e37aad26
https://doi.org/10.1016/j.jsbmb.2004.03.079
https://doi.org/10.1016/j.jsbmb.2004.03.079