Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thomas W Spiesser"'
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 4, p e1004223 (2015)
Maintenance of cellular size is a fundamental systems level process that requires balancing of cell growth with proliferation. This is achieved via the cell division cycle, which is driven by the sequential accumulation and destruction of cyclins. Th
Externí odkaz:
https://doaj.org/article/e33e4f83401b4a7fa8e61526e2b65991
Publikováno v:
PLoS ONE, Vol 5, Iss 4, p e10203 (2010)
BACKGROUND: DNA replication begins at specific locations called replication origins, where helicase and polymerase act in concert to unwind and process the single DNA filaments. The sites of active DNA synthesis are called replication forks. The dens
Externí odkaz:
https://doaj.org/article/a8cdcd13b5254194825957662d9e7659
Autor:
Stephan O Adler, Thomas W Spiesser, Friedemann Uschner, Ulrike Münzner, Jens Hahn, Marcus Krantz, Edda Klipp
Publikováno v:
FEMS yeast research. 22(1)
The cell division cycle in eukaryotic cells is a series of highly coordinated molecular interactions that ensure that cell growth, duplication of genetic material, and actual cell division are precisely orchestrated to give rise to two viable progeny
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea4f306167d25972d4c02f5565cbc6f
https://pubmed.ncbi.nlm.nih.gov/35617157
https://pubmed.ncbi.nlm.nih.gov/35617157
Publikováno v:
Biotechnology Journal. 11:1158-1168
Systems biology holds the promise to integrate multiple sources of information in order to build ever more complete models of cellular function. To do this, the field must overcome two significant challenges. First, the current strategy to model aver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0371b0642db004cbf715c59891e46de9
https://doi.org/10.1002/biot.201500344
https://doi.org/10.1002/biot.201500344
Publikováno v:
FEBS Journal; Vol 279
The cell division cycle orchestrates cellular growth and division. The machinery underpinning the cell division cycle is well characterized, but the actual cue(s) driving the cell division cycle remains unknown. In rapidly growing and dividing yeast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f25c7703d7a19bbdfa41ba3b45004d4
Replication Origins and Timing of Temporal Replication in Budding Yeast: How to Solve the Conundrum?
Publikováno v:
Current Genomics
Similarly to metazoans, the budding yeast Saccharomyces cereviasiae replicates its genome with a defined timing. In this organism, well-defined, site-specific origins, are efficient and fire in almost every round of DNA replication. However, this str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bef90a134605f8c24487a6b31878889e
https://doi.org/10.2174/138920210791110942
https://doi.org/10.2174/138920210791110942
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 11, Iss 4, p e1004223 (2015)
PLoS Computational Biology, Vol 11, Iss 4, p e1004223 (2015)
Maintenance of cellular size is a fundamental systems level process that requires balancing of cell growth with proliferation. This is achieved via the cell division cycle, which is driven by the sequential accumulation and destruction of cyclins. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fb554de33ce1863d4108a979eaecaa9
https://pubmed.ncbi.nlm.nih.gov/25910075
https://pubmed.ncbi.nlm.nih.gov/25910075
Autor:
Thomas W, Spiesser, Edda, Klipp
Publikováno v:
Genome informatics. International Conference on Genome Informatics. 24
DNA replication is a fundamental process that is tightly regulated during the cell cycle. In budding yeast it starts from multiple origins of replication and proceeds in a timely fashion according to a reproducible temporal program until the entire D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7e0a360db8857a02a99c5f8916fc4fe
https://pubmed.ncbi.nlm.nih.gov/22081599
https://pubmed.ncbi.nlm.nih.gov/22081599
Publikováno v:
Bioinformatics
Summary: SensA is a web-based application for sensitivity analysis of mathematical models. The sensitivity analysis is based on metabolic control analysis, computing the local, global and time-dependent properties of model components. Interactive vis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7948ab64e7d3cdb60b88b3805f57fe97
https://doi.org/10.1093/bioinformatics/btu378
https://doi.org/10.1093/bioinformatics/btu378
Autor:
Edda Klipp, Thomas W. Spiesser
Publikováno v:
Genome Informatics 2010.
DNA replication is a fundamental process that is tightly regulated during the cell cycle. In budding yeast it starts from multiple origins of replication and proceeds in a timely fashion according to a reproducible temporal program until the entire D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7fea1c9d036ecc85c85ab298bd12762
https://doi.org/10.1142/9781848166585_0015
https://doi.org/10.1142/9781848166585_0015