Zobrazeno 1 - 10 of 75 pro vyhledávání: '"Thomas W O'Brien"'
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Akademický článek
Llama-Derived Single Domain Antibodies Specific for Abrus Agglutinin
Autor: James P. Carney, Rachael Bernstein, Eric A. E. Garber, Jennifer L. Walker, Thomas W. O’Brien, Alena Calm, Jinny L. Liu, Ellen R. Goldman, Scott Walper, Dan Zabetakis, George P. Anderson
Publikováno v: Toxins, Vol 3, Iss 11, Pp 1405-1419 (2011)
Llama derived single domain antibodies (sdAb), the recombinantly expressed variable heavy domains from the unique heavy-chain only antibodies of camelids, were isolated from a library derived from llamas immunized with a commercial abrin toxoid prepa
Externí odkaz: https://doaj.org/article/c19eeac1a53e4b2ba31c8a97e669acff
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4
EVALUATION OF A MULTIPLEX ARBOVIRUS SEROLOGY ASSAY AS A TOOL FOR SEROSURVEILLANCE
Autor: Neeraja Venkateswaran, Thomas W O’Brien, Wiilam Max Nelson, Kodumudi S Venkateswaran
Publikováno v: The Journal of Immunology. 204:159.31-159.31
Arthropod-borne viruses (Arboviruses) constitute a serious threat to global health by causing significant mortality and morbidity. Recent years have seen the emergence of arboviruses due to climatic changes, the adaptation of mosquitoes, and other ar
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b7ddb6614ea21e82ceafe2871717bd2
https://doi.org/10.4049/jimmunol.204.supp.159.31
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6
Utility
Autor: Thomas W. O'Brien, John F. Sarkesain
Publikováno v: Modeling and Simulation Support for System of Systems Engineering Applications. :515-529
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c9b6a442a1182109efbdce5bdd2257b9
https://doi.org/10.1002/9781118501757.ch19
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7
Depletion of the Central Metabolite NAD Leads to Oncosis-mediated Cell Death
Autor: Thomas W. O'Brien, Yang Xiao, Christopher Del Nagro, Linda Rangell, Mike Reichelt
Publikováno v: Journal of Biological Chemistry. 289:35182-35192
Depletion of the central metabolite NAD in cells results in broad metabolic defects leading to cell death and is a proposed novel therapeutic strategy in oncology. There is, however, a limited understanding of the underlying mechanisms that connect d
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6cbb4056d4065fecd311a585ed633d
https://doi.org/10.1074/jbc.m114.580159
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8
A Thematic Analysis of 'Love' and 'Truth' in Caritas in Veritate
Autor: Thomas W O'Brien
Publikováno v: Political Theology. 14:573-588
The encyclical Caritas in veritate uses love as its guiding theological theme, and this innovation exposes the encyclical to critical reflections from some of the greatest theological minds of the mid-twentieth century. This article attempts to reviv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78d4c3cc8d359e84875f83ae43a66209
https://doi.org/10.1179/1462317x13z.00000000020
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Abstract P3-04-24: Identification of preclinical mechanisms driving acquired resistance to selective ERa degraders (SERDs), CDK4/6 inhibitors, or to combinations of both agents
Autor: Anneleen Daemen, Thomas W. O'Brien, Lori Friedman, Christy C. Ong, Yang Xiao
Publikováno v: Cancer Research. 77:P3-04
Estrogen positive (ER+) breast cancer accounts for the majority of all breast cancers and standard practice is treatment with endocrine therapy. Recently a series of CDK4/6 inhibitors have emerged that can be effectively combined with estrogen modula
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c95c8a579612176f026aa4030d722658
https://doi.org/10.1158/1538-7445.sabcs16-p3-04-24
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