Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Thomas W Lynch"'
Publikováno v:
Semantic Keyword-Based Search on Structured Data Sources ISBN: 9783319279312
International KEYSTONE Conference
International KEYSTONE Conference
The Deep Web is constituted by data accessible through web pages, but not readily indexable by search engines, as they are returned in dynamic pages. In this paper we propose a framework for accessing Deep Web sources, represented as relational table
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::884382e433a557c2230baa300d3c66b7
https://doi.org/10.1007/978-3-319-27932-9_3
https://doi.org/10.1007/978-3-319-27932-9_3
Publikováno v:
Journal of Molecular Biology. 330:493-502
Integration host factor (IHF) is a DNA–bending protein that recognizes its cognate sites through indirect readout. Previous studies have shown that binding of wild-type (WT)-IHF is disrupted by a T to A mutation at the center position of a conserve
Autor:
Stephen G. Sligar, Thomas W. Lynch
Publikováno v:
Journal of Biological Chemistry. 275:30561-30565
In this report, the effects of osmotic pressure on BamHI cognate binding and catalysis were investigated and compared with a previous study on EcoRI (Robinson, C. R. and Sligar, S. G. (1998) Proc. Natl. Acad. Sci. U.S.A. 95, 2186-2191). Our observati
Publikováno v:
IEEE Transactions on Computers. 47:913-926
We report on the successful application of a mechanical theorem prover to the problem of verifying the division microcode program used on the AMD5/sub K/86 microprocessor. The division algorithm is an iterative shift and subtract type. It was impleme
Autor:
Michael J. Schulte, Thomas W. Lynch
Publikováno v:
Reliable Computing. 2:133-138
High radix on-line arithmetic provides an efficient method for performing variable-precision arithmetic. It can be implemented on conventional microprocessors using sequences of three operand instructions. This paper presents software support for hig
Autor:
Thomas W. Lynch, Earl E. Swartzlander
Publikováno v:
IEEE Transactions on Computers. 41:931-939
The design of the 56-b significant adder used in the Advanced Micro Devices Am29050 microprocessor is described. Originally implemented in a 1- mu m design role CMOS process, it evaluates 56-b sums in well under 4 ns. The adder employs a novel method
Autor:
Annette Gilchrist, Alan H. Kadish, Thomas W. Lynch, David A. Dean, Roger Villuendas, Jason Ng, Rishi Arora, David Gordon, J. Andrew Wasserstrom, Gary L. Aistrup, Rui Zhou, Jeffrey J. Goldberger, Ivan Cokic, Steven Mottl
The parasympathetic nervous system is thought to play a key role in atrial fibrillation (AF). Since parasympathetic signalling is primarily mediated by the heterotrimeric G-protein, Galpha(i)betagamma, we hypothesized that targeted inhibition of Galp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3cd834715e0ab769377a4688c7a1228
https://europepmc.org/articles/PMC2709464/
https://europepmc.org/articles/PMC2709464/
Autor:
Phoebe A. Rice, Ying Z. Pigli, Joseph H.A. Vissers, Arabela A. Grigorescu, Claire Wyman, Dejan Ristic, Thomas W Lynch
Publikováno v:
Nucleic Acids Research, 37(2), 557-567. Oxford University Press
Nucleic Acids Research
Nucleic Acids Research
Rad51 is the central catalyst of homologous recombination in eukaryotes and is thus critical for maintaining genomic integrity. Recent crystal structures of filaments formed by Rad51 and the closely related archeal RadA and eubacterial RecA proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::467251ff33f6efb3cb30c36da42dca61
https://pure.eur.nl/en/publications/28ab8a70-1704-4fb8-ae56-6e279326bbdc
https://pure.eur.nl/en/publications/28ab8a70-1704-4fb8-ae56-6e279326bbdc
Autor:
Thomas W. Lynch
Publikováno v:
Workshop on Physics and Computation.
This paper explores the implications of a Maxwell’s demon successfully applying a priori knowledge about the motion of particles to a thermodynamic system. The assumption that the knowledge can be recorded symbolically is used to calculate the numb
Autor:
Phoebe A. Rice, Adam B. Conway, Ying Zhang, Thomas W Lynch, Cindy W. Fung, Gary S. Fortin, Lorraine S. Symington
Publikováno v:
Nature structuralmolecular biology. 11(8)
Rad51, the major eukaryotic homologous recombinase, is important for the repair of DNA damage and the maintenance of genomic diversity and stability. The active form of this DNA-dependent ATPase is a helical filament within which the search for homol