Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Thomas W H Kay"'
Autor:
John Virostko, Richard C Craddock, Jonathan M Williams, Taylor M Triolo, Melissa A Hilmes, Hakmook Kang, Liping Du, Jordan J Wright, Mara Kinney, Jeffrey H Maki, Milica Medved, Michaela Waibel, Thomas W H Kay, Helen E Thomas, Siri Atma W Greeley, Andrea K Steck, Daniel J Moore, Alvin C Powers
Publikováno v:
PLoS ONE, Vol 16, Iss 8, p e0256029 (2021)
Magnetic resonance imaging (MRI) has detected changes in pancreas volume and other characteristics in type 1 and type 2 diabetes. However, differences in MRI technology and approaches across locations currently limit the incorporation of pancreas ima
Externí odkaz:
https://doaj.org/article/dbc9dc62256a40189372bb1641b4d5fe
Autor:
Charmaine J Simeonovic, Sarah K Popp, Lora M Starrs, Debra J Brown, Andrew F Ziolkowski, Barbara Ludwig, Stefan R Bornstein, J Dennis Wilson, Alberto Pugliese, Thomas W H Kay, Helen E Thomas, Thomas Loudovaris, Fui Jiun Choong, Craig Freeman, Christopher R Parish
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0191360 (2018)
Type 1 diabetes (T1D) is an autoimmune disease in which insulin-producing beta cells in pancreatic islets are progressively destroyed. Clinical trials of immunotherapies in recently diagnosed T1D patients have only transiently and partially impacted
Externí odkaz:
https://doaj.org/article/3bfbd0d7d48b4557a8441d019c004f28
Autor:
Cassandra Bazile, Magdy M. Abdel Malik, Courtney Ackeifi, Randy L. Anderson, Roy W. Beck, Marc Y. Donath, Sanjoy Dutta, Joseph A. Hedrick, Stephen R. Karpen, Thomas W. H. Kay, Thomas Marder, Marjana Marinac, Jennifer McVean, Robert Meyer, Jeremy Pettus, Teresa Quattrin, Ruud H. J. Verstegen, Joshua A. Vieth, Esther Latres
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Type 1 diabetes (T1D) is an autoimmune disease characterized by the destruction of insulin-producing β-cells in the pancreas. This destruction leads to chronic hyperglycemia, necessitating lifelong insulin therapy to manage blood glucose levels. Typ
Externí odkaz:
https://doaj.org/article/3d839e45f08449c58283852ff8e122f0
Autor:
Anna Galligan, Amir Iravani, Arian Lasocki, Roslyn Wallace, Alison M. Weppler, Nirupa Sachithanandan, Cherie Chiang, Peter G. Colman, John Wentworth, Lavinia Spain, George Au-Yeung, Belinda Lee, Thomas W. H. Kay, Rodney J. Hicks, Shahneen Sandhu, Balasubramanian Krishnamurthy
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
IntroductionHypophysitis is reported in 8.5%–14% of patients receiving combination immune checkpoint inhibition (cICI) but can be a diagnostic challenge. This study aimed to assess the role of routine diagnostic imaging performed during therapeutic
Externí odkaz:
https://doaj.org/article/fb5d37ec95e142d795c4d6ee92680ea7
Autor:
Balasubramanian Krishnamurthy, Matthew Lacorcia, Thomas W. H. Kay, Helen E. Thomas, Stuart I. Mannering
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Type 1 diabetes (T1D) is a T-cell mediated autoimmune disease. Short-term treatment with agents targeting T cells, B cells and inflammatory cytokines to modify the disease course resulted in a short-term pause in disease activity. Lessons learnt from
Externí odkaz:
https://doaj.org/article/0e1b8fe12e0848439e27932c9bce2a87
Autor:
David J. De George, Tingting Ge, Balasubramaniam Krishnamurthy, Thomas W. H. Kay, Helen E. Thomas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Type 1 diabetes is an autoimmune disease with onset from early childhood. The insulin-producing pancreatic beta cells are destroyed by CD8+ cytotoxic T cells. The disease is challenging to study mechanistically in humans because it is not possible to
Externí odkaz:
https://doaj.org/article/6fda57144c434ff1bfc7c70a1820ea51
Autor:
Anna Galligan, Roslyn Wallace, Balasubramanian Krishnamurthy, Thomas W. H. Kay, Nirupa Sachithanandan, Cherie Chiang, Shahneen Sandhu, Rodney J. Hicks, Amir Iravani
Publikováno v:
Cancers, Vol 15, Iss 24, p 5803 (2023)
Background: FDG-PET/CT used for immune checkpoint inhibitor (ICI) response assessment can incidentally identify immune-related adverse events (irAEs), including thyroiditis. This study aimed to correlate the time course of FDG-PET/CT evidence of thyr
Externí odkaz:
https://doaj.org/article/f232cc202b4d41869107a892b6498a5d
Autor:
Rahul D. Barmanray, Joanna Y. Gong, Mervyn Kyi, Dev Kevat, Mohammad A. Islam, Anna Galligan, Georgina R. Manos, Indu V. Nair, Nayomi Perera, Nicholas K. Adams, Ashvin Nursing, Annabelle M. Warren, Peter S. Hamblin, Richard J. MacIsaac, Elif I. Ekinci, Balasubramanian Krishnamurthy, Harin Karunajeewa, Kirsty Buising, Kumar Visvanathan, Thomas W. H. Kay, Spiros Fourlanos
Publikováno v:
Internal Medicine Journal. 53:27-36
Autor:
Rahul D, Barmanray, Joanna Y, Gong, Mervyn, Kyi, Dev, Kevat, Mohammad A, Islam, Anna, Galligan, Georgina R, Manos, Indu V, Nair, Nayomi, Perera, Nicholas K, Adams, Ashvin, Nursing, Annabelle M, Warren, Peter S, Hamblin, Richard J, MacIsaac, Elif I, Ekinci, Balasubramanian, Krishnamurthy, Harin, Karunajeewa, Kirsty, Buising, Kumar, Visvanathan, Thomas W H, Kay, Spiros, Fourlanos
Publikováno v:
Internal medicine journalReferences.
A relationship between diabetes, glucose and COVID-19 outcomes has been reported in international cohorts. This study aimed to assess the relationship between diabetes, hyperglycaemia and patient outcomes in those hospitalised with COVID-19 during th
Autor:
Anojian Koneshamoorthy, Dilan Seniveratne-Epa, Genevieve Calder, Matthew Sawyer, Thomas W. H. Kay, Stephen Farrell, Thomas Loudovaris, Lina Mariana, Davis McCarthy, Ruqian Lyu, Xin Liu, Peter Thorn, Jason Tong, Lit Kim Chin, Margaret Zacharin, Alison Trainer, Shelby Taylor, Richard J. MacIsaac, Nirupa Sachithanandan, Helen E. Thomas, Balasubramanian Krishnamurthy
Publikováno v:
Frontiers in Endocrinology. 13
We present a case of an obese 22-year-old man with activating GCK variant who had neonatal hypoglycemia, re-emerging with hypoglycemia later in life. We investigated him for asymptomatic hypoglycemia with a family history of hypoglycemia. Genetic tes