Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Thomas Vuillemin"'
Autor:
David Brühlmann, Jürgen Hemberger, Zeynep Manco, Alessandra D'Angelo, Eugenio Galano, Jonathan Souquet, Thomas Vuillemin, Abhijeet Satwekar, Markus Sauer, Angelo Palmese, Martin Jordan, Hervé Broly
Publikováno v:
Biotechnology and Bioengineering. 116:1017-1028
Glycosylation, a critical product quality attribute, may affect the efficacy and safety of therapeutic proteins in vivo. Chinese hamster ovary fed-batch cell culture batches yielded consistent glycoprofiles of a Fc-fusion antibody comprizing three di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acce949db3e51d8af6de126a0d3e8e20
https://doi.org/10.1002/bit.26930
https://doi.org/10.1002/bit.26930
Autor:
Rebecca Parker, David Brühlmann, Jonathan Souquet, Tobias Haas, Thomas Vuillemin, Anaïs Muhr, Martin Jordan, Hervé Broly, Serena Torre, Markus Sauer, Fabio La Neve, Blanka Bucsella, Antonio Lembo, Franka Kalman, Jürgen Hemberger
Publikováno v:
Journal of biotechnology. 252
Glycosylation plays a pivotal role in pharmacokinetics and protein physiochemical characteristics. In particular, effector functions including antibody-dependent cell-mediated cytotoxicity (ADCC) can be desired, and it has been described that high-ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f30bfa2c2536997f1f4f66a9e39c1ed
https://pubmed.ncbi.nlm.nih.gov/28465212
https://pubmed.ncbi.nlm.nih.gov/28465212