Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Thomas Vernier, P."'
Publikováno v:
In Bioelectrochemistry December 2024 160
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract The detailed molecular mechanisms underlying the permeabilization of cell membranes by pulsed electric fields (electroporation) remain obscure despite decades of investigative effort. To advance beyond descriptive schematics to the developme
Externí odkaz:
https://doaj.org/article/21c6eeaee9d24b368b451817b016cfd4
Publikováno v:
In Bioelectrochemistry June 2015 103:98-102
Publikováno v:
Frontiers in Molecular Biosciences, Vol 4 (2017)
We extend the multiscale spatiotemporal heat map strategies originally developed for interpreting molecular dynamics simulations of well-structured proteins to liquids such as lipid bilayers and solvents. Our analysis informs the experimental and the
Externí odkaz:
https://doaj.org/article/e8ffb0499119451392cc2bde6d3edf3a
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181002 (2017)
This study examined the effect of 5 ns electric pulses on macroscopic ionic currents in whole-cell voltage-clamped adrenal chromaffin cells. Current-voltage (I-V) relationships first established that the early peak inward current was primarily compos
Externí odkaz:
https://doaj.org/article/85153b46c02d4f4782df4133acaaad78
Autor:
Emilie Louise Hansen, Esin Bengisu Sozer, Stefania Romeo, Stine Krog Frandsen, P Thomas Vernier, Julie Gehl
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0128034 (2015)
Externí odkaz:
https://doaj.org/article/4937cacf1f5d44fb9783f6796bbd322a
Autor:
Emilie Louise Hansen, Esin Bengisu Sozer, Stefania Romeo, Stine Krog Frandsen, P Thomas Vernier, Julie Gehl
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0122973 (2015)
Electroporation, a method for increasing the permeability of membranes to ions and small molecules, is used in the clinic with chemotherapeutic drugs for cancer treatment (electrochemotherapy). Electroporation with calcium causes ATP (adenosine triph
Externí odkaz:
https://doaj.org/article/fbc694240e494ac3babce15725a1ce05
Autor:
Mayya Tokman, Jane HyoJin Lee, Zachary A Levine, Ming-Chak Ho, Michael E Colvin, P Thomas Vernier
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e61111 (2013)
Electroporation is the formation of permeabilizing structures in the cell membrane under the influence of an externally imposed electric field. The resulting increased permeability of the membrane enables a wide range of biological applications, incl
Externí odkaz:
https://doaj.org/article/d8f81dbb207443db897fa26dd59803e2
Autor:
Dong Yin, Wangrong G Yang, Jack Weissberg, Catherine B Goff, Weikai Chen, Yoshio Kuwayama, Amanda Leiter, Hongtao Xing, Antonie Meixel, Daria Gaut, Fikret Kirkbir, David Sawcer, P Thomas Vernier, Jonathan W Said, Martin A Gundersen, H Phillip Koeffler
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43891 (2012)
Nanosecond pulsed electric fields (nsPEF) induce apoptotic pathways in human cancer cells. The potential therapeutic effective of nsPEF has been reported in cell lines and in xenograft animal tumor model. The present study investigated the ability of
Externí odkaz:
https://doaj.org/article/b4aae9c2b5254419b1ea48d99254aad2
Autor:
Stefania Romeo, Luigi Zeni, Maurizio Sarti, Anna Sannino, Maria Rosaria Scarfì, P Thomas Vernier, Olga Zeni
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28419 (2011)
Intense nanosecond pulsed electric fields (nsPEFs) interact with cellular membranes and intracellular structures. Investigating how cells respond to nanosecond pulses is essential for a) development of biomedical applications of nsPEFs, including can
Externí odkaz:
https://doaj.org/article/7fe8758bbeab49af9c37e04e24fc3ada