Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thomas V. Magee"'
Autor:
Jemy A. Gutierrez, Wei Liu, Sylvie Perez, Gang Xing, Gabriele Sonnenberg, Kou Kou, Matt Blatnik, Richard Allen, Yan Weng, Nicholas B. Vera, Kristin Chidsey, Arthur Bergman, Veena Somayaji, Collin Crowley, Michelle F. Clasquin, Anu Nigam, Melissa A. Fulham, Derek M. Erion, Trenton T. Ross, William P. Esler, Thomas V. Magee, Jeffrey A. Pfefferkorn, Kendra K. Bence, Morris J. Birnbaum, Gregory J. Tesz
Publikováno v:
Molecular Metabolism, Vol 48, Iss , Pp 101196- (2021)
Objective: Recent studies suggest that excess dietary fructose contributes to metabolic dysfunction by promoting insulin resistance, de novo lipogenesis (DNL), and hepatic steatosis, thereby increasing the risk of obesity, type 2 diabetes (T2D), non-
Externí odkaz:
https://doaj.org/article/83d51c2650cb4492a69b4c32dbb702cc
Autor:
Elnaz Menhaji-Klotz, Thomas V. Magee
Cardiovascular diseases (CVDs) are the number one cause of death globally according to the World Health Organization. They account for approximately 30% of all global deaths and incur great medical costs. Chronic or congestive heart failure (CHF) rem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d6c23b8b423d616ded98f0353ef5d9
https://doi.org/10.1039/9781782622390-00186
https://doi.org/10.1039/9781782622390-00186
Autor:
Samuel J. Danishefsky, John J. Masters, Wendy B. Young, J. T. Link, Lawrence B. Snyder, Thomas V. Magee, David K. Jung, Richard C. A. Isaacs, William G. Bornmann, Cheryl A. Alaimo, Craig A. Coburn, Martin J. Di Grandi
Publikováno v:
Journal of the American Chemical Society. 118:2843-2859
An intramolecular Heck reaction (90 → 91) serves as the key step in the total synthesis of the titled compounds. The synthetic route is based on utilizing the Wieland−Miescher ketone (5) as a matrix to provide the C and D rings of the targets and
Publikováno v:
Angewandte Chemie International Edition in English. 34:1723-1726
The present invention provides two basic routes for the total synthesis of taxol having the structure: ##STR1## The present invention also provides the intermediates produced in the above processes, processes for synthesizing these intermediates as w
Autor:
Thomas V. Magee, Duane F. Zinkel
Publikováno v:
Journal of the American Oil Chemists' Society. 69:321-324
The composition of the acidic components was determined for a cross section of distilled tall oil products produced in the United States. The composition varied widely as a result of different process designs and operations. Filtration of those produ
Publikováno v:
The Journal of Organic Chemistry. 57:3274-3276
The Wieland-Miescher ketone lends itself to conversion, in a few steps, to intermediates which could well be useful for a synthesis of taxol (1) and analogs thereof
Autor:
Kim Huard, Allyn T. Londregan, Gregory Tesz, KevinB. Bahnck, Thomas V. Magee, David Hepworth, Jana Polivkova, Steven B. Coffey, BrandonA. Pabst, James R. Gosset, Anu Nigam, Kou Kou, Hao Sun, Kyuha Lee, Michael Herr, Markus Boehm, PhilipA. Carpino, Bryan Goodwin, Christian Perreault, Qifang Li
Publikováno v:
Journal of Medicinal Chemistry; Sep2015, Vol. 58 Issue 18, p7164-7172, 9p
Autor:
Thomas V. Magee, Sharon L. Ripp, Bryan Li, Richard A. Buzon, Lou Chupak, Thomas J. Dougherty, Steven M. Finegan, Dennis Girard, Anne E. Hagen, Michael J. Falcone, Kathleen A. Farley, Karl Granskog, Joel R. Hardink, Michael D. Huband, Barbara J. Kamicker, Takushi Kaneko, Michael J. Knickerbocker, Jennifer L. Liras, Andrea Marra, Ivy Medina
Publikováno v:
Journal of Medicinal Chemistry; Dec2009, Vol. 52 Issue 23, p7446-7457, 12p
Autor:
Duane F. Zinkel, Thomas V. Magee
Publikováno v:
Phytochemistry. 26:769-774
The resin acid components of P. strobus needles were isolated, and the major constituents identified as labdenoic diterpenes. In addition to anticopalic and strobic acids previously reported in the needles, 3-oxoanticopalic, 3β-acetoxyanticopalic, 3
Publikováno v:
Phytochemistry. 24:1273-1277
Labdane diterpene acids were found to be the major resin acid components in Pinus nigra needles of various seed sources. The major constituents have been identified as 4-epiimbricataloic acid, manoyl oxide 19-oic acid, 4-epicommunic acid, and 15-mono