Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Thomas V. Holohan"'
Autor:
Thomas V. Holohan, Christopher J. Horvath, Tia DeFeo-Fraulini, H. Nicholas Marsh, Robert G. Schaub, Sleiman BouFakhreddine, James C. Gilbert, Judith M. Healy, Renta Hutabarat, Patricia G. Merlino
Publikováno v:
Circulation. 116:2678-2686
Background— ARC1779 is a therapeutic aptamer antagonist of the A1 domain of von Willebrand Factor (vWF), the ligand for receptor glycoprotein 1b on platelets. ARC1779 is being developed as a novel antithrombotic agent for use in patients with acute
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87c290da4be7e22fd6f1cdee69273417
https://doi.org/10.1161/circulationaha.107.724864
https://doi.org/10.1161/circulationaha.107.724864
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 83:1868-1874
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cd952165381e95c71ea2460f39d9ca
https://doi.org/10.1210/jc.83.6.1868
https://doi.org/10.1210/jc.83.6.1868
Autor:
Julie Rovner, Anthony S Fauci, Robert H Fletcher, Suzanne W Fletcher, Tariq Malik, Thomas V Holohan, Margaret A Hamburg
Publikováno v:
The Lancet. 348:1001-1010
To call the way health care is organised and delivered in the United States a system is charitable, at best. The arrangements under which most Americans today receive medical services are a patchwork based more on historical accidents and political c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c15cd8c139ac2dc14c3d0ef3999daee
https://doi.org/10.1016/s0140-6736(96)08389-4
https://doi.org/10.1016/s0140-6736(96)08389-4
Autor:
Thomas V. Holohan
Publikováno v:
Clinical Research and Regulatory Affairs. 13:37-42
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10ea71fed3f9c6998dffe765a9ff127c
https://doi.org/10.3109/10601339609019628
https://doi.org/10.3109/10601339609019628
Autor:
James C Gilbert, Tia DeFeo-Fraulini, Renta M Hutabarat, Christopher J Horvath, Patricia G Merlino, H N Marsh, Judy M Healy, Sleiman B Fahkreddine, Thomas V Holohan, Robert Schaub
Publikováno v:
Circulation. 116
Background: The prominent role played by vWF in arterial thrombogenesis suggests that vWF inhibition may offer an effective adjunct therapy to PCI in ACS patients. ARC1779 is a PEG-conjugated aptamer that blocks platelet activation through inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::451dff9731f4bd509856c89e14c598a5
https://doi.org/10.1161/circ.116.suppl_16.ii_724
https://doi.org/10.1161/circ.116.suppl_16.ii_724
Publikováno v:
Southern medical journal. 98(11)
Objective Although claims databases are not representative of all care delivery, their predisposition toward serious unintended injury can complement resource-intensive chart reviews and guide patient safety initiatives. Materials and methods Non-Vet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::223af8753da56e83a6c3266b8ed2d0be
https://pubmed.ncbi.nlm.nih.gov/16351024
https://pubmed.ncbi.nlm.nih.gov/16351024
Autor:
Thomas V. Holohan
Publikováno v:
The Lancet. 350:151-152
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63b9443a22aedd9d73e34905044830bd
https://doi.org/10.1016/s0140-6736(97)25028-2
https://doi.org/10.1016/s0140-6736(97)25028-2
Autor:
Thomas V. Holohan
Publikováno v:
The Lancet. 351:1665
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::653dff70d6001ee514fdb637217e64e1
https://doi.org/10.1016/s0140-6736(98)25022-7
https://doi.org/10.1016/s0140-6736(98)25022-7
Autor:
Nicholas P. Anagnou, Gerald L. Messerschmidt, Byron Chesbro, Ross A. Abrams, Albert B. Deisseroth, T. C. Shan, Richard S. Ungerleider, Joseph A. Fontana, Thomas V. Holohan, Robert W. Makuch, Fred Appelbaum, J. F. Ódonnell, Daniel G. Wright
Publikováno v:
Cancer. 62:795-801
The use of histocompatability antigen (HLA)-matched platelets has been advocated for the support of thrombocytopenic cancer patients. We randomized 78 newly diagnosed cancer patients prospectively (before thrombocytopenia) to receive either HLA-match
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11feab249421d45ce872f1548a51f2b6
https://doi.org/10.1002/1097-0142(19880815)62:4<795::aid-cncr2820620426>3.0.co
https://doi.org/10.1002/1097-0142(19880815)62:4<795::aid-cncr2820620426>3.0.co
Publikováno v:
Blood. 58:122-128
A retrospective review of HLA antibody testing and transfusion records of 100 cancer patients who required extensive platelet support revealed that 27 of 100 patients exhibited positive HLA antibody tests; only 13 remained positive on repetitive exam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b2117a3d7dd94fca7d92d5894bc3da2
https://doi.org/10.1182/blood.v58.1.122.122
https://doi.org/10.1182/blood.v58.1.122.122