Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Thomas V. Alfredson"'
Autor:
Thomas V. Alfredson, Bruce Griffin, Robert Towne, Denis J. Kertesz, Allassan Abubakari, Norman H. Dyson, Michelle Elliott
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 19:1653-1668
Separation of the stereoisomers of azalanstat (RS-21607-197), a substituted imidazolyl-1,3-dioxolane which acts as a potent inhibitor of lanosterol 14α-demethylase in cholesterol biosynthesis, and its ketal tosylate intermediate was achieved by chir
Publikováno v:
Journal of Chromatographic Science. 32:132-138
Multiple peak formation and interconversion in the liquid chromatographic (LC) analysis of triostin A and its under-N-methylated synthetic analogue, [N-MeCys3,N-MeCys7]-TANDEM (MCTANDEM), are investigated as a function of column temperature. Slow int
Publikováno v:
Tetrahedron Letters. 35:1011-1014
The pure R-(+)-enantiomer of 5-lipoxygenase inhibitor Zileuton was prepared by diastereoselective methyl Grignard addition to an aldonitrone bearing a D-gulofuranose-derived chiral auxiliary. Addition of the Lewis acid trimethylaluminum leads to a re
Publikováno v:
Applied Magnetic Resonance. 2:159-178
The DNA complexes of triostin A, echinomycin, and the monoquinoline (1QN) and bisquinoline (2QN) biosynthesized derivatives of echinomycin were investigated by optical detection of triplet-state magnetic resonance (ODMR) spectroscopy, with the quinox
Publikováno v:
SPIE Proceedings.
A linear correlation between spectroscopic and thermodynamic properties of systems is rarely encountered. In triplet state ODMR studies of various DNA complexes of echinomycin, a quinoxaline-containing cyclic depsipeptide bis-intercalating antibiotic
Publikováno v:
Biopolymers. 31(14)
The conformational heterogeneity of several quinoxaline antibiotics, a class of naturally occurring quinoxaline peptides with antitumor properties, and their synthetic analogues was investigated in polar and nonpolar solvents by high performance liqu
Publikováno v:
Biochemistry. 30(40)
The polymeric DNA and model duplex oligonucleotide complexes of the bisquinoline analogue of echinomycin (2QN) have been studied by optical detection of triplet-state magnetic resonance (ODMR) spectroscopy, with the quinoline chromophores of the drug
Autor:
Jean-Louis Excoffier, Michael J. Waring, Marye e. Adaskaveg, Thomas V. Alfredson, August H. Maki
Publikováno v:
Journal of chromatography. 507
Numerical formats for evaluation of spectral purity and for spectral comparison of ultraviolet diode-array detector data, together with library search routines, were applied to the liquid chromatographic analysis of echinomycin, triostin A and their
Autor:
Thomas V. Alfredson
Publikováno v:
Journal of Chromatography A. 218:715-728
The application of high-performance liquid chromatographic column switching techniques for hydrocarbon group-type separations of petroleum samples was investigated. Model compounds were employed to study hydrocarbon class separations using normal bon
Publikováno v:
Journal of Liquid Chromatography. 5:489-524
Two types of high performance aqueous size exclusion columns have recently been developed, one a rigid spherical silica-based packing containing a new hydrophilic bonded phase (MicroPak TSK Gel Type SW) and the other an organic-based, semi-rigid gel