Výsledky vyhledávání - "Thomas V O'Halloran"

Akademický článek

Semi-quantitative elemental imaging of corrosion products from bioabsorbable Mg vascular implants in vivo

Autor: Weilue He, Keith W. MacRenaris, Adam Griebel, Maria P. Kwesiga, Erico Freitas, Amani Gillette, Jeremy Schaffer, Thomas V. O'Halloran, Roger J. Guillory II

Publikováno v: Bioactive Materials, Vol 43, Iss , Pp 225-239 (2025)

While metal materials historically have served as permanent implants and were designed to avoid degradation, next generation bioabsorbable metals for medical devices such as vascular stents are under development, which would elute metal ions and corr

Externí odkaz: https://doaj.org/article/b6b07332102543659ca3207dae54f158

Zobrazit plný text záznamu

Akademický článek

Structural and mechanistic basis of zinc regulation across the E. coli Zur regulon.

Autor: Benjamin A Gilston, Suning Wang, Mason D Marcus, Mónica A Canalizo-Hernández, Elden P Swindell, Yi Xue, Alfonso Mondragón, Thomas V O'Halloran

Publikováno v: PLoS Biology, Vol 12, Iss 11, p e1001987 (2014)

Commensal microbes, whether they are beneficial or pathogenic, are sensitive to host processes that starve or swamp the prokaryote with large fluctuations in local zinc concentration. To understand how microorganisms coordinate a dynamic response to

Externí odkaz: https://doaj.org/article/f3850d6e0af944b6981c9546c2fcd0fc

Zobrazit plný text záznamu

Akademický článek

Identification of a new epitope in uPAR as a target for the cancer therapeutic monoclonal antibody ATN-658, a structural homolog of the uPAR binding integrin CD11b (αM).

Autor: Xiang Xu, Yuan Cai, Ying Wei, Fernando Donate, Jose Juarez, Graham Parry, Liqing Chen, Edward J Meehan, Richard W Ahn, Andrey Ugolkov, Oleksii Dubrovskyi, Thomas V O'Halloran, Mingdong Huang, Andrew P Mazar

Publikováno v: PLoS ONE, Vol 9, Iss 1, p e85349 (2014)

The urokinase plasminogen activator receptor (uPAR) plays a role in tumor progression and has been proposed as a target for the treatment of cancer. We recently described the development of a novel humanized monoclonal antibody that targets uPAR and

Externí odkaz: https://doaj.org/article/0173507ab52c4bee81931476328e41db

Zobrazit plný text záznamu

Akademický článek

Nano-encapsulation of arsenic trioxide enhances efficacy against murine lymphoma model while minimizing its impact on ovarian reserve in vitro and in vivo.

Autor: Richard W Ahn, Susan L Barrett, Meera R Raja, Jennifer K Jozefik, Lidia Spaho, Haimei Chen, Marcel B Bally, Andrew P Mazar, Michael J Avram, Jane N Winter, Leo I Gordon, Lonnie D Shea, Thomas V O'Halloran, Teresa K Woodruff

Publikováno v: PLoS ONE, Vol 8, Iss 3, p e58491 (2013)

Advances in cancer therapy have increased the rate of survival of young cancer patients; however, female lymphoma patients frequently face a temporary or permanent loss of fertility when treated with traditional cytotoxic agents. The potential loss o

Externí odkaz: https://doaj.org/article/629387cc7d7a46b4b5bc03d165b05f02

Zobrazit plný text záznamu

Akademický článek

Zinc Dynamics during Drosophila Oocyte Maturation and Egg Activation

Autor: Qinan Hu, Francesca E. Duncan, Andrew B. Nowakowski, Olga A. Antipova, Teresa K. Woodruff, Thomas V. O'Halloran, Mariana F. Wolfner

Publikováno v: iScience, Vol 23, Iss 7, Pp 101275- (2020)

Summary: Temporal fluctuations in zinc concentration are essential signals, including during oogenesis and early embryogenesis. In mammals, zinc accumulation and release are required for oocyte maturation and egg activation, respectively. Here, we de

Externí odkaz: https://doaj.org/article/3d9d031f0a8a4ec59f97d7b0ba062250

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání