Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Thomas U. Greiner"'
Autor:
Thomas U. Greiner, Ara Koh, Eduard Peris, Mattias Bergentall, Malin E.V. Johansson, Gunnar C. Hansson, Daniel J. Drucker, Fredrik Bäckhed
Publikováno v:
Molecular Metabolism, Vol 83, Iss , Pp 101924- (2024)
Objectives: Gut microbiota increases energy availability through fermentation of dietary fibers to short-chain fatty acids in conventionally raised mice. Energy deficiency in germ-free (GF) mice increases glucagon-like peptide-1 (GLP-1) levels, which
Externí odkaz:
https://doaj.org/article/263a379437f5472790b2cc60cb953f8c
Autor:
Jenny M. Hoffmann, John R. Grünberg, Ann Hammarstedt, Tobias Kroon, Thomas U. Greiner, Stefanie Maurer, Ivet Elias, Vilborg Palsdottir, Fatima Bosch, Jeremie Boucher, Shahram Hedjazifar, Ulf Smith
Publikováno v:
Molecular Metabolism, Vol 32, Iss , Pp 15-26 (2020)
Objective: Bone morphogenetic protein 4 (BMP4) adeno-associated viral vectors of serotype 8 (AAV8) gene therapy targeting the liver prevents the development of obesity in initially lean mice by browning the large subcutaneous white adipose tissue (WA
Externí odkaz:
https://doaj.org/article/f9ddf0eaf4ad46ecababbbec31f4fdd4
Autor:
Natalia Petersen, Thomas U. Greiner, Lola Torz, Angie Bookout, Marina Kjærgaard Gerstenberg, Carlos M. Castorena, Rune Ehrenreich Kuhre
Publikováno v:
Metabolites, Vol 12, Iss 1, p 39 (2022)
Obesity is caused by prolonged energy surplus. Current anti-obesity medications are mostly centralized around the energy input part of the energy balance equation by increasing satiety and reducing appetite. Our gastrointestinal tract is a key organ
Externí odkaz:
https://doaj.org/article/99ffd87cd8244a898ed0ba5f3c707ec3
Autor:
Thomas U. Greiner, Fredrik Bäckhed
Publikováno v:
Molecular Metabolism, Vol 5, Iss 9, Pp 753-758 (2016)
Background: The gut microbiota is associated with several of metabolic diseases, including obesity and type 2 diabetes and affects host physiology through distinct mechanisms. The microbiota produces a vast array of metabolites that signal to host ce
Externí odkaz:
https://doaj.org/article/d1ec0e9640694e9ab854ddb2295476e2
Autor:
Tulika Arora, Udo Wegmann, Anup Bobhate, Ying Shiuan Lee, Thomas U. Greiner, Daniel J. Drucker, Arjan Narbad, Fredrik Bäckhed
Publikováno v:
Molecular Metabolism, Vol 5, Iss 8, Pp 725-730 (2016)
Objective: The enteroendocrine hormone glucagon-like peptide 1 (GLP-1) is an attractive anti-diabetic therapy. Here, we generated a recombinant Lactococcus lactis strain genetically modified to produce GLP-1 and investigated its ability to improve gl
Externí odkaz:
https://doaj.org/article/b048ec4f1b7d4a9d9cb7601cb75249e3
Autor:
Karl Alex Hedin, Hongbin Zhang, Vibeke Kruse, Vanessa Emily Rees, Fredrik Bäckhed, Thomas U. Greiner, Ruben Vazquez-Uribe, Morten Otto Alexander Sommer
Obesity is rapidly increasing within the global population and is one of the leading causes of chronic diseases, including type 2 diabetes (T2D), non-alcoholic fatty liver disease, and cardiovascular diseases. Glucagon-like peptide-1 receptor (GLP-1R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3526aef22339500c9e1e5aa9fcc98f11
https://doi.org/10.1101/2022.12.21.521368
https://doi.org/10.1101/2022.12.21.521368
Autor:
Vilborg Palsdottir, Ann Hammarstedt, Thomas U. Greiner, Ivet Elias, Stefanie Maurer, Tobias Kroon, Fatima Bosch, Shahram Hedjazifar, John R. Grünberg, Jenny M. Hoffmann, Jeremie Boucher, Ulf Smith
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 32, Iss, Pp 15-26 (2020)
Molecular Metabolism, Vol 32, Iss, Pp 15-26 (2020)
Objective Bone morphogenetic protein 4 (BMP4) adeno-associated viral vectors of serotype 8 (AAV8) gene therapy targeting the liver prevents the development of obesity in initially lean mice by browning the large subcutaneous white adipose tissue (WAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c229035283332b81cbcc4ac30ce3089
http://europepmc.org/articles/PMC6933264
http://europepmc.org/articles/PMC6933264
Autor:
Katja Hess, Jacqueline Ameri, Henrik Semb, Eric D. Bankaitis, Matthew E. Bechard, Pia Nyeng, Thomas U. Greiner, Zarah M. Löf-Öhlin, Christopher V.E. Wright
Publikováno v:
Nature Cell Biology. 19:1313-1325
Apicobasal polarity is known to affect epithelial morphogenesis and cell differentiation, but it remains unknown how these processes are mechanistically orchestrated. We find that ligand-specific EGFR signalling via PI(3)K and Rac1 autonomously modul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::819fcd21c44779832fd56e2f5a4ccb5c
https://doi.org/10.1038/ncb3628
https://doi.org/10.1038/ncb3628
Autor:
Anup Bobhate, Arjan Narbad, Udo Wegmann, Tulika Arora, Thomas U. Greiner, Fredrik Bäckhed, Ying Shiuan Lee, Daniel J. Drucker
Publikováno v:
Molecular Metabolism, Vol 5, Iss 8, Pp 725-730 (2016)
Molecular Metabolism
Molecular Metabolism
Objective The enteroendocrine hormone glucagon-like peptide 1 (GLP-1) is an attractive anti-diabetic therapy. Here, we generated a recombinant Lactococcus lactis strain genetically modified to produce GLP-1 and investigated its ability to improve glu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e50af855ff766db15b6eae40127ad77d
Autor:
Anant Mamidi, Jenny Johansson, Henrik Semb, Zarah Löf Öhlin, Thomas U. Greiner, Gokul Kesavan, Silvia Lommel, Wan Chun Li, Oliver Lieven
Publikováno v:
Development. 141:685-696
Delamination plays a pivotal role during normal development and cancer. Previous work has demonstrated that delamination and epithelial cell movement within the plane of an epithelium are associated with a change in cellular phenotype. However, how t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07525167d0cf51c0e42aaf524e350187
https://doi.org/10.1242/dev.100297
https://doi.org/10.1242/dev.100297